Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anke Muller-Fahrnow"'
Autor:
Daria B. Kokh, Leigh A. Stoddart, Robert M. Cooke, Dorothee Andres, Rebecca C. Wade, Gerhard F. Ecker, Steve Hill, Wilhelmus E. A. de Witte, Marta Amaral, Elena Segala, Bernhard Knasmueller, Matthias Frech, Reggie Bosma, Laura H. Heitman, S. Kashif Sadiq, Anke Muller-Fahrnow, Chris de Graaf, Indira Nederpelt, Dong Guo, Adriaan P. IJzerman, Victoria Georgi, Elizabeth C. M. de Lange, Yin Cheong Wong, Lars Richter, Doris A. Schuetz, Rob Leurs
Publikováno v:
Drug Discovery Today, 22(6), 896-911
Schuetz, D A, de Witte, W E A, Wong, Y C, Knasmueller, B, Richter, L, Kokh, D B, Sadiq, S K, Bosma, R, Nederpelt, I, Heitman, L H, Segala, E, Amaral, M, Guo, D, Andres, D, Georgi, V, Stoddart, L A, Hill, S, Cooke, R M, de Graaf, C, Leurs, R, Frech, M, Wade, R C, de Lange, E C M, IJzerman, A P, Müller-Fahrnow, A & Ecker, G F 2017, ' Kinetics for Drug Discovery : an industry-driven effort to target drug residence time ', Drug Discovery Today, vol. 22, no. 6, pp. 896-911 . https://doi.org/10.1016/j.drudis.2017.02.002
Drug Discovery Today
Schuetz, D A, de Witte, W E A, Wong, Y C, Knasmueller, B, Richter, L, Kokh, D B, Sadiq, S K, Bosma, R, Nederpelt, I, Heitman, L H, Segala, E, Amaral, M, Guo, D, Andres, D, Georgi, V, Stoddart, L A, Hill, S, Cooke, R M, de Graaf, C, Leurs, R, Frech, M, Wade, R C, de Lange, E C M, IJzerman, A P, Müller-Fahrnow, A & Ecker, G F 2017, ' Kinetics for Drug Discovery : an industry-driven effort to target drug residence time ', Drug Discovery Today, vol. 22, no. 6, pp. 896-911 . https://doi.org/10.1016/j.drudis.2017.02.002
Drug Discovery Today
A considerable number of approved drugs show non-equilibrium binding characteristics, emphasizing the potential role of drug residence times for in vivo efficacy. Therefore, a detailed understanding of the kinetics of association and dissociation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0f239e285cfffe51e30eaad7eaed15
https://doi.org/10.1016/j.drudis.2017.02.002
https://doi.org/10.1016/j.drudis.2017.02.002
Autor:
Bernd Radüchel, Róbert Király, Ernö Brücher, Anke Muller-Fahrnow, Johannes Platzek, Zsolt Baranyai, Martina Schäfer, Éva Csajbók, István Bányai
Publikováno v:
Inorganic Chemistry. 42:2342-2349
Several Bi(III) complexes are used in medicine as drugs. Bi(DO3A-Bu) has recently been proposed as a nonionic contrast agent in X-ray imaging (H(3)DO3A-Bu = 10-[2,3-dihydroxy-(1-hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7,-triacetic ac