Supplementary Table 1 from Anetumab Ravtansine: A Novel Mesothelin-Targeting Antibody–Drug Conjugate Cures Tumors with Heterogeneous Target Expression Favored by Bystander Effect

Autor: Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier

PDF - 118K, Supplementary Table S1. Mesothelin staining intensity in FFPE tissues of human primary ovarian cancer, pancreatic cancer and mesothelioma.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3851a39590f944f943652dd8cf92bb67
https://doi.org/10.1158/1535-7163.22499859

Supplementary Materials and Methods and Supplementary Figure Legends from Anetumab Ravtansine: A Novel Mesothelin-Targeting Antibody–Drug Conjugate Cures Tumors with Heterogeneous Target Expression Favored by Bystander Effect

Autor: Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier

PDF - 117K, Supplementary materials and methods, figure legends for supplementary figures and table.

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https://doi.org/10.1158/1535-7163.22499862.v1

Rational Design of Single Copy Expression Cassettes in Defined Chromosomal Sites Overcomes Intraclonal Cell-to-Cell Expression Heterogeneity and Ensures Robust Antibody Production

Autor: Sabrina Herrmann, Anke Mayer-Bartschmid, Dagmar Wirth, Natascha Gödecke, Mark Trautwein, Hansjörg Hauser

Publikováno v: ACS synthetic biology. 10(1)

The expression of endogenous genes as well as transgenes depends on regulatory elements within and surrounding genes as well as their epigenetic modifications. Members of a cloned cell population often show pronounced cell-to-cell heterogeneity with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a7e07382f3ba7f349cd4dbc20f37ee
https://pubmed.ncbi.nlm.nih.gov/33382574

The German national consensus on wound documentation and outcomes: Rationale, working programme and current status

Autor: Matthias Augustin, H. Schuster, M. Schindzielorz, C. Tonn, U. Imkamp, A. von Lienen, J. Bunse, R. Aschoff, M. May, B. Lange-Asschenfeldt, W. Vanscheidt, E. Valesky, Jochen Schmitt, R. U. Peter, F. Kamperhoff, T. Hirsch, T.R. Neubert, Christos C. Zouboulis, R. Kaufmann, S. Glau, M. Bischoff, S. Eming, H. Fansa, Kristina Heyer, A. Nast, B. Hartmann, Anke Mayer, R. Nagel, S. Gass, K. Waldvogel-Röcker, D. Hochlenert, H. Diener, T. Horn, T. Wild, T. Goerge, J. Helfrich, F. Flesch, M. Schmidt, S. Langer, C. van Montfrans, Eike Sebastian Debus, V. Großkopf, Kerstin Protz, Christine Blome, F. Gaiser, A.D. Niederbichler, M. Storck, Florian C. Beikert, T. Petzold, S. Gartner, Lisa Goepel, T. Eberlein, A. Sindrilaru, K. Scharffetter-Kochanek, C. Janetzko, E. Schäfer, C. Hampel-Kalthoff, Katharina Herberger, V. Gerber, W. Tigges, K.C. Münter, M. Jünger, J. Dissemond, J.O. Jost, A. Risse

Publikováno v: Wound Medicine. 7:8-13

Chronic wounds are of high socio-economic importance. Accurate and efficient treatment includes the use of outcomes measures in clinical care and in research. To date, consented standards for documentation of chronic wounds, agreements on interpretat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4195c2e72dfac34875616492ced0d683
https://doi.org/10.1016/j.wndm.2015.03.008

Cumulative Life Course Impairment (CLCI): A new concept to characterize persistent patient burden in chronic wounds

Autor: Matthias Augustin, Lisa Goepel, Katharina Herberger, Katrin Baade, Kristina Heyer, Anke Mayer

Publikováno v: Wound Medicine. 1:2-6

Cumulative Life Course Impairment (CLCI) is a theoretical construct referring to the non-reversible burden of a chronic skin disease over time. In some patients and situations, this burden may lead to chronic impairment and missed opportunities and,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2bb8da908cb2525d1ef37a49c7ee965
https://doi.org/10.1016/j.wndm.2013.06.001