Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anke Kurreck"'
Autor:
Sarah Westarp, Felix Brandt, Lena Neumair, Christina Betz, Amin Dagane, Sebastian Kemper, Christoph R. Jacob, Peter Neubauer, Anke Kurreck, Felix Kaspar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Modern, highly evolved nucleoside-processing enzymes are known to exhibit perfect regioselectivity over the glycosylation of purine nucleobases at N9. We herein report an exception to this paradigm. Wild-type nucleoside phosphorylases also f
Externí odkaz:
https://doaj.org/article/cf8b68e2ec444d2394e0b591ed81067f
Autor:
Mathias Ziersch, Dominik Harms, Lena Neumair, Anke Kurreck, Reimar Johne, C.-Thomas Bock, Jens Kurreck
Publikováno v:
Viruses, Vol 16, Iss 9, p 1378 (2024)
Hepatitis E virus (HEV) poses a significant global health threat, with an estimated 20 million infections occurring annually. Despite being a self-limiting illness, in most cases, HEV infection can lead to severe outcomes, particularly in pregnant wo
Externí odkaz:
https://doaj.org/article/356afb2ed52c41129d13f50d69be4f89
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Catalytically active inclusion bodies (CatIBs) produced in Escherichia coli are an interesting but currently underexplored strategy for enzyme immobilization. They can be purified easily and used directly as stable and reusable heterogenous
Externí odkaz:
https://doaj.org/article/07f86537fc4c442f8b39ad9c8c5b8c25
Autor:
Felix Kaspar, Felix Brandt, Sarah Westarp, Lea Eilert, Sebastian Kemper, Anke Kurreck, Peter Neubauer, Christoph R. Jacob, Anett Schallmey
Publikováno v:
Angewandte Chemie International Edition. 62
Biocatalytic nucleoside (trans-)glycosylations catalyzed by nucleoside phosphorylases have graduated to a practical and convenient approach to the preparation of modified nucleosides, which are important pharmaceuticals for the treatment of various c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50212f94cb71fd607f542714463e0354
https://doi.org/10.1002/anie.202218492
https://doi.org/10.1002/anie.202218492
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b884093812ce02c6beec55658b2ea13
https://doi.org/10.1007/978-1-0716-2930-7_8
https://doi.org/10.1007/978-1-0716-2930-7_8
Autor:
Anna P. Lehmann, Christoph Köllmann, Anett Schallmey, Anke Kurreck, Patrick Pausch, Felix Kaspar, Peter Neubauer, Gert Bange, Daniel B. Werz, Margarita Seeger, Sebastian Kemper, Sarah Westarp
Publikováno v:
ACS Catalysis. 11:10830-10835
The growing demand for 4'-modified nucleoside analogs in medicinal and biological chemistry is contrasted by the challenging synthetic access to these molecules and the lack of efficient diversification strategies. Herein, we report the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e083c3fadb8960d9ae6790a6c489c211
https://doi.org/10.1021/acscatal.1c02589
https://doi.org/10.1021/acscatal.1c02589
Autor:
Simon, Seidel, Mariano Nicolas, Cruz-Bournazou, Sebastian, Groß, Julia Katharina, Schollmeyer, Anke, Kurreck, Stefan, Krauss, Peter, Neubauer
Publikováno v:
Advances in biochemical engineering/biotechnology. 182
Typical product development in biotechnological laboratories is a distributed and versatile process. Today's biotechnological laboratory devices are usually equipped with multiple sensors and a variety of interfaces. The existing software for biotech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c4f721e2f50f92b529e2c78a4a88659
https://pubmed.ncbi.nlm.nih.gov/35861884
https://pubmed.ncbi.nlm.nih.gov/35861884
Publikováno v:
Biochemistry. 60:1573-1577
Enzyme-catalyzed reactions sometimes display curvature in their Eyring plots in the absence of denaturation, indicative of a change in activation heat capacity. However, the effects of pH and (de)protonation on this phenomenon have remained unexplore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2ea87e4c4669432d0aeaa2aadcd93d5
https://doi.org/10.1021/acs.biochem.1c00156
https://doi.org/10.1021/acs.biochem.1c00156
Autor:
Katja F. Winkler, Lena Panse, Caroline Maiwald, Josefine Hayeß, Pascal Fischer, Maryke Fehlau, Peter Neubauer, Anke Kurreck
Publikováno v:
Journal of Biological Chemistry. :104746
Enzymes from thermophilic organisms are interesting biocatalysts for a wide variety of applications in organic synthesis, biotechnology and molecular biology. Next to an increased stability at elevated temperatures, they were described to show a wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf035e462ce05f241dcceabaa6a74e3
https://doi.org/10.1016/j.jbc.2023.104746
https://doi.org/10.1016/j.jbc.2023.104746
Autor:
Yikun Mei, Dongwei Wu, Johanna Berg, Beatrice Tolksdorf, Viola Roehrs, Anke Kurreck, Thomas Hiller, Jens Kurreck
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6071
Lung cancer still has one of the highest morbidity and mortality rates among all types of cancer. Its incidence continues to increase, especially in developing countries. Although the medical field has witnessed the development of targeted therapies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac660d0911db3f11349fd14583a12d77
https://doi.org/10.3390/ijms24076071
https://doi.org/10.3390/ijms24076071