Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Anke J. Laskewitz"'
1
Akademický článek
Glucose kinetics in the collagen-induced arthritis model: an all-in-one model to assess both efficacy and metabolic side effects of glucocorticoids.
Autor: Erik J M Toonen, Anke J Laskewitz, Theo H van Dijk, Aycha Bleeker, Aldo Grefhorst, Annelies E Schouten, Ellen A J Bastiaanssen, Dov B Ballak, Marije I Koenders, Cindy van Doorn, Monique A J van der Vleuten, Marie-Jose C van Lierop, Albert K Groen, Wim H A Dokter
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e98684 (2014)
Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory drugs, but chronic use is hampered by metabolic side effects. Therefore, there is an urgent medical need for improved GCs that are as effective as classical GCs but have a bett
Externí odkaz: https://doaj.org/article/6ad073e9b532425b9c32ea1bda826964
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2
Akademický článek
Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.
Autor: Marie-José C van Lierop, Wynand Alkema, Anke J Laskewitz, Rein Dijkema, Hans M van der Maaden, Martin J Smit, Ralf Plate, Paolo G M Conti, Christan G J M Jans, C Marco Timmers, Constant A A van Boeckel, Scott J Lusher, Ross McGuire, Rene C van Schaik, Jacob de Vlieg, Ruben L Smeets, Claudia L Hofstra, Annemieke M H Boots, Marcel van Duin, Benno A Ingelse, Willem G E J Schoonen, Aldo Grefhorst, Theo H van Dijk, Folkert Kuipers, Wim H A Dokter
Publikováno v: PLoS ONE, Vol 7, Iss 11, p e48385 (2012)
Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGR
Externí odkaz: https://doaj.org/article/6e9843e211b74a5b893e7e79339992e9
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3
Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport
Autor: Arne Dikkers, Uwe J. F. Tietge, Anke J. Laskewitz, Rick Havinga, Ido P. Kema, Carolien Out, Claude van der Ley, Renze Boverhof, H.J. Verkade, Folkert Kuipers, Hendrik Wolters, Albert K. Groen
Publikováno v: Journal of Hepatology, 61(2), 351-357. ELSEVIER SCIENCE BV
Background & Aims: Glucocorticoids, produced by the adrenal gland under control of the hypothalamic-pituitary-adrenal axis, exert their metabolic actions largely via activation of the glucocorticoid receptor (GR). Synthetic glucocorticoids are widely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19d17849bd22cbe65f898dbd501b06d
https://doi.org/10.1016/j.jhep.2014.03.025
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4
Chronic Prednisolone Treatment Aggravates Hyperglycemia in Mice Fed a High-Fat Diet but Does Not Worsen Dietary Fat-Induced Insulin Resistance
Autor: Vincent W. Bloks, Theo H. van Dijk, Albert K. Groen, Folkert Kuipers, Dirk-Jan Reijngoud, Wim H. A. Dokter, Marijke Schreurs, Aldo Grefhorst, Anke J. Laskewitz, Marie-Jose C. van Lierop
Publikováno v: Endocrinology, 153(8), 3713-3723. The Endocrine Society
Endocrinology, 153(8), 3713-3723. ENDOCRINE SOC
Endocrinology, 153(8), 3713-3723. Endocrine Society
Synthetic glucocorticoids such as prednisolone have potent antiinflammatory actions. Unfortunately, these drugs induce severe adverse effects in patients, many of which resemble features of the metabolic syndrome, such as insulin resistance. In this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea91c395666fa1b7543de9871c61e980
https://doi.org/10.1210/en.2011-1891
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5
Archaeal and Bacterial SecD and SecF Homologs Exhibit Striking Structural and Functional Conservation
Autor: Anke J. Laskewitz, Reinhard Klein, Mechthild Pohlschroder, Nicholas J. Hand
Publikováno v: Journal of Bacteriology. 188:1251-1259
The majority of secretory proteins are translocated into and across hydrophobic membranes via the universally conserved Sec pore. Accessory proteins, including the SecDF-YajC Escherichia coli membrane complex, are required for efficient protein secre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73804064d2aeedf051cfa275803df7f
https://doi.org/10.1128/jb.188.4.1251-1259.2006
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6
Glucose Kinetics in the Collagen-Induced Arthritis Model: An All-in-One Model to Assess Both Efficacy and Metabolic Side Effects of Glucocorticoids
Autor: Theo H. van Dijk, Wim H. A. Dokter, Marije I. Koenders, Monique van der Vleuten, Dov B. Ballak, Anke J. Laskewitz, Aldo Grefhorst, Ellen A. J. Bastiaanssen, Cindy van Doorn, Marie-Jose C. van Lierop, Albert K. Groen, Annelies E. Schouten, Aycha Bleeker, Erik J M Toonen
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e98684 (2014)
PLoS One, 9, 9
PLoS ONE, 9(9). Public Library of Science
PLoS One (print), 9(9). Public Library of Science
PLoS ONE, 9(9):e98684. PUBLIC LIBRARY SCIENCE
PLoS One, 9
PLoS ONE
Contains fulltext : 138117.pdf (Publisher’s version ) (Open Access) Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory drugs, but chronic use is hampered by metabolic side effects. Therefore, there is an urgent medical need f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3093093a628114874d178b806cbebf
https://doi.org/10.1371/journal.pone.0098684
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7
A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice
Autor: Vincent W. Bloks, Folkert Kuipers, Dirk-Jan Reijngoud, Aldo Grefhorst, Anke J. Laskewitz, T. H. van Dijk, Theo Boer, Albert K. Groen
Publikováno v: Laboratory animals, 47(2), 79-88. SAGE Publications Ltd
Laboratory Animals, 47(2), 79-88
Laboratory Animals, 47(2), 79-88. SAGE Publications Ltd
The aetiology of insulin resistance is still an enigma. Mouse models are frequently employed to study the underlying pathology. The most commonly used methods to monitor insulin resistance are the HOMA-IR, glucose or insulin tolerance tests and the h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef79b9050e18a40bceeb48294d74ddbe
https://pure.amc.nl/en/publications/a-novel-approach-to-monitor-glucose-metabolism-using-stable-isotopically-labelled-glucose-in-longitudinal-studies-in-mice(b09bd738-4121-4abb-b8c1-4c1b33b01f72).html
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8
Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index
Autor: Martin J. Smit, Jacob de Vlieg, Ruben L. Smeets, René C. van Schaik, Hans van der Maaden, Willem G.E.J. Schoonen, Constant A. A. van Boeckel, Rein Dijkema, Wynand Alkema, Theo H. van Dijk, Scott J. Lusher, Claudia L. Hofstra, Annemieke M. H. Boots, Wim H. A. Dokter, Benno A. Ingelse, Marcel van Duin, Folkert Kuipers, Paolo Conti, Christan G.J.M. Jans, Marie-Jose van Lierop, C. Marco Timmers, Ralf Plate, Aldo Grefhorst, Ross McGuire, Anke J. Laskewitz
Publikováno v: PLoS ONE, 7(11):e48385. Public Library of Science
PLoS ONE, 7(11):e48385. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 7, Iss 11, p e48385 (2012)
PLoS One, 7
PLoS ONE
PLoS ONE, 7(11). Public Library of Science
PLoS One, 7, 11
PLoS One (print), 7(11). Public Library of Science
Contains fulltext : 103595.pdf (Publisher’s version ) (Open Access) Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, deve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4a324fb2b1362114eafd292311c633
https://doi.org/10.1371/journal.pone.0048385
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