Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anke H.W. Essing"'
Autor:
Pauline Schneider, Patricia Garrido Castro, Sandra M. Pinhanços, Mark Kerstjens, Eddy H. vanRoon, Anke H.W. Essing, M. Emmy M. Dolman, Jan J. Molenaar, Rob Pieters, Ronald W. Stam
Publikováno v:
eJHaem, Vol 1, Iss 2, Pp 527-536 (2020)
Abstract MLL‐rearranged acute lymphoblastic leukemia (ALL) represents a highly aggressive ALL subtype, characterized by aberrant DNA methylation patterns. DNA methyltransferase inhibitors, such as decitabine have previously been demonstrated to be
Externí odkaz:
https://doaj.org/article/17ab3a3cd77a4a4f9267630c85d65ee2
Autor:
Nil A. Schubert, Sander R. van Hooff, Linda Schild, Kimberley Ober, Marjolein Hortensius, Kim van den Handel, Anke H.W. Essing, Bianca Koopmans, Manon Boeije, Natalie Proost, Marieke van de Ven, Selina Jansky, Sabine A. Stainczyk, Umut H. Toprak, Frank Westermann, Selma Eising, Jan J. Molenaar, Marlinde L. van den Boogaard
Publikováno v:
bioRxiv
Homozygous inactivation of the CDKN2A locus is one of the most common genomic aberrations in human cancer. The locus codes for two unrelated and distinctly regulated proteins: p14ARF and p16INK4a, which inhibit MDM2 and CDK4/6, respectively. Loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9d40a29722a1f30d92c3ace3cc4803
https://zenodo.org/record/5912979
https://zenodo.org/record/5912979
