Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anke H. W. Essing"'
Autor:
Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M. Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M. Kholosy, Bianca Koopmans, Anke H. W. Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H. Schulte, Frank Westermann, Jan J. Molenaar, Katleen De Preter, Frank Speleman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
In high-risk neuroblastoma cases, gains in chromosome 17q are common. Here, the authors investigate the epigenomics and transcriptomics of neuroblastoma, identifying TBX2 as a core regulatory circuitry component enhancing the reactivation of DREAM ta
Externí odkaz:
https://doaj.org/article/536b907629694780b1f507b113373066
Autor:
Judith Wienke, S Nierkens, Miranda P Dierselhuis, Jan J Molenaar, Annelisa M Cornel, Ester Dunnebach, Damon A Hofman, Sanjukta Das, Satyaki Sengupta, Femke van den Ham, Josephine G M Strijker, Denise A M H van den Beemt, Anke H W Essing, Bianca Koopmans, Sem A G Engels, Vania Lo Presti, Celina S Szanto, Rani E George, Sebastiaan van Heesch
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Immunotherapy in high-risk neuroblastoma (HR-NBL) does not live up to its full potential due to inadequate (adaptive) immune engagement caused by the extensive immunomodulatory capacity of HR-NBL. We aimed to tackle one of the most notable
Externí odkaz:
https://doaj.org/article/7142ba69053342a98bcc3622acf2b968
Autor:
Ronald W. Stam, M. Emmy M. Dolman, Anke H. W. Essing, Pauline Schneider, Mark Kerstjens, Rob Pieters, P. Castro, Jan J. Molenaar, Sandra S Mimoso Pinhancos, Eddy H.J. van Roon
Publikováno v:
eJHaem. 1:527-536
Autor:
Annelisa M Cornel, Ester Dunnebach, Damon A Hofman, Sanjukta Das, Satyaki Sengupta, Femke van den Ham, Judith Wienke, Josephine G M Strijker, Denise A M H van den Beemt, Anke H W Essing, Bianca Koopmans, Sem A G Engels, Vania Lo Presti, Celina S Szanto, Rani E George, Jan J Molenaar, Sebastiaan van Heesch, Miranda P Dierselhuis, S Nierkens
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e005002
BackgroundImmunotherapy in high-risk neuroblastoma (HR-NBL) does not live up to its full potential due to inadequate (adaptive) immune engagement caused by the extensive immunomodulatory capacity of HR-NBL. We aimed to tackle one of the most notable
Autor:
Dieter Deforce, Dries Rombaut, Karen Verboom, Jan J. Molenaar, Suzanne Vanhauwaert, Pieter Mestdagh, Johan van Nes, G Schleiermacher, Bieke Decaesteker, Johannes H. Schulte, Filip Van Nieuwerburgh, Franki Speleman, Christophe Van Neste, Rogier Versteeg, Jolien De Wyn, Carl Herrmann, Katleen De Preter, Geertrui Denecker, Moritz Gartlgruber, Kaat Durinck, Daniel Dreidax, Pauline Depuydt, Fanny De Vloed, Valentina Boeva, Wouter Van Loocke, Waleed M. Kholosy, Frank Westermann, Bianca Koopmans, Emmy Dolman, Anke H. W. Essing, Carolina de Carvalho Nunes, Siebe Loontiens, Anton G. Henssen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature communications, 9(1). Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications
Nature communications, 9(1). Nature Publishing Group
NATURE COMMUNICATIONS
Chromosome 17q gains are almost invariably present in high-risk neuroblastoma cases. Here, we perform an integrative epigenomics search for dosage-sensitive transcription factors on 17q marked by H3K27ac defined super-enhancers and identify TBX2 as t
Autor:
Sarah F Janssen, Sophie J F van der Spek, Jacoline B Ten Brink, Anke H W Essing, Theo G M F Gorgels, Peter J van der Spek, Nomdo M Jansonius, Arthur A B Bergen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83345 (2013)
BACKGROUND: The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain ventricles and produces the cerebrospinal fluid (CSF), which is crucial for brain homeost
Externí odkaz:
https://doaj.org/article/39fe7811bb2545488305027e683a19f6
Autor:
Pauline, Schneider, Patricia Garrido, Castro, Sandra M, Pinhanços, Mark, Kerstjens, Eddy H, van Roon, Anke H W, Essing, M Emmy M, Dolman, Jan J, Molenaar, Rob, Pieters, Ronald W, Stam
Publikováno v:
EJHaem. 1(2)
Autor:
Nitish D. Fagoe, Ruben Eggers, August B. Smit, H. M. Eggink, Elske H. P. Franssen, S.-J. J. Zijlstra, R.E. van Kesteren, Kasper C. D. Roet, Anke H. W. Essing, F. M. de Bree, Joost Verhaagen
Publikováno v:
Journal of Neuroscience, 33(27), 11116-11135. Society for Neuroscience
Journal of Neuroscience, 33, 11116-11135. Society for Neuroscience
Roet, K C D, Franssen, E H P, de Bree, F M, Essing, A H, Zijlstra, S J, Fagoe, N D, Eggink, H M, Eggers, R, Smit, A B, van Kesteren, R E & Verhaagen, J 2013, ' A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons ', The Journal of Neuroscience, vol. 33, no. 27, pp. 11116-11135 . https://doi.org/10.1523/JNEUROSCI.1002-13.2013
The Journal of Neuroscience, 33(27), 11116-11135. Society for Neuroscience
Roet, K C D, Franssen, E H P, de Bree, F M, Essing, A H, Zijlstra, S J, Fagoe, N D, Eggink, H M, Eggers, R, Smit, A B, van Kesteren, R E & Verhaagen, J 2013, ' A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons ', Journal of Neuroscience, vol. 33, no. 27, pp. 11116-11135 . https://doi.org/10.1523/JNEUROSCI.1002-13.2013
Journal of Neuroscience, 33, 11116-11135. Society for Neuroscience
Roet, K C D, Franssen, E H P, de Bree, F M, Essing, A H, Zijlstra, S J, Fagoe, N D, Eggink, H M, Eggers, R, Smit, A B, van Kesteren, R E & Verhaagen, J 2013, ' A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons ', The Journal of Neuroscience, vol. 33, no. 27, pp. 11116-11135 . https://doi.org/10.1523/JNEUROSCI.1002-13.2013
The Journal of Neuroscience, 33(27), 11116-11135. Society for Neuroscience
Roet, K C D, Franssen, E H P, de Bree, F M, Essing, A H, Zijlstra, S J, Fagoe, N D, Eggink, H M, Eggers, R, Smit, A B, van Kesteren, R E & Verhaagen, J 2013, ' A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons ', Journal of Neuroscience, vol. 33, no. 27, pp. 11116-11135 . https://doi.org/10.1523/JNEUROSCI.1002-13.2013
Olfactory ensheathing cells (OECs) have neuro-restorative properties in animal models for spinal cord injury, stroke, and amyotrophic lateral sclerosis. Here we used a multistep screening approach to discover genes specifically contributing to the re
Autor:
Dick F. Swaab, Gideon F. Meerhoff, Anke H. W. Essing, Pieter Houba, Chris G. Kruse, Kerstin T.S. Wirz, Koen Bossers, Jeroen W. van Dongen, Joost Verhaagen
Publikováno v:
Brain: a journal of neurology, 133, 3699-3723. Oxford University Press
Brain, 133(Part 12), 3699-3723. Oxford University Press
Brain, 133(Part 12), 3699-3723. Oxford University Press
Using the Braak staging for neurofibrillary changes as an objective indicator of the progression of Alzheimer's disease, we have performed a systematic search for global gene expression changes in the prefrontal cortex during the course of Alzheimer'
Autor:
Bianca Koopmans, Lindy Vernooij, Laurel T. Bate-Eya, Jan J. Molenaar, M. Emmy M. Dolman, Ronald W. Stam, Daphne Lelieveld, Mark Kerstjens, Anke H. W. Essing, Huib N. Caron, David A. Egan, Lindy K. Alles
Publikováno v:
Cancer Research. 78:2630-2630
BACKGROUND: The anti-apoptotic protein B cell lymphoma/leukaemia 2 (BCL-2) is highly expressed in the majority of all neuroblastomas. In previous preclinical studies, we have shown that treatment of BCL-2-dependent neuroblastoma with BCL-2 inhibitors