Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anke Gregus"'
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background STAT1 is an intracellular signaling molecule that is crucially involved in the regulation of the innate immune system by activation of defense mechanisms against microbial pathogens. Phosphorylation-dependent activation of the STA
Externí odkaz:
https://doaj.org/article/65d7b0b077bd42f48f145c6de6a94af1
Autor:
Lena Sophie Behrendsen, Priyanka Rajeev Menon, Muhammad Jawad Khan, Anke Gregus, Oliver Wirths, Thomas Meyer, Julia Staab
Publikováno v:
BMC Molecular and Cell Biology, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that promotes cell proliferation and immunomodulation in untransformed cells and maintains stemness of transformed cells, facilitating
Externí odkaz:
https://doaj.org/article/22ad33cd6e5a4e95937739b42cec51d3
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Unphosphorylated signal transducer and activator of transcription 1 (U-STAT1) has been reported to elicit a distinct gene expression profile as compared to tyrosine-phosphorylated STAT1 (P-STAT1) homodimers. However, the impact of
Externí odkaz:
https://doaj.org/article/616275c055264bdfbdc779cfddf93301
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1868(12)
Signal transducer and activator of transcription 3 (STAT3) gain-of-function mutations have been widely reported in patients with tumors and haematological malignancies. However, the molecular mechanisms of these pathogenic mutations remain largely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d17f0e5351b8953ae40ee8b31d4dd3
https://pubmed.ncbi.nlm.nih.gov/34390807
https://pubmed.ncbi.nlm.nih.gov/34390807
Autor:
Anke Gregus, M. Frankenberg-Schwager
Publikováno v:
International journal of radiation biology. 88(11)
Mammography X-rays are known to induce DNA double-strand breaks (DSB) whose error-free recombinational repair requires the function of the tumour repressor genes BRCA1 (breast-cancer-associated gene 1) and BRCA2 (breast-cancer-associated gene 2). Sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965799dc27f560c61b92020ccaf47d05
https://pubmed.ncbi.nlm.nih.gov/22788243
https://pubmed.ncbi.nlm.nih.gov/22788243