Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Anke, Van der Perren"'
Autor:
Teresa Torre-Muruzabal, Jens Devoght, Chris Van den Haute, Bert Brône, Anke Van der Perren, Veerle Baekelandt
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Aggregation of alpha-synuclein (α-SYN) is the pathological hallmark of several diseases named synucleinopathies, including Parkinson’s disease (PD), which is the most common neurodegenerative motor disorder. Alpha-SYN has been linked to s
Externí odkaz:
https://doaj.org/article/ee9667357d7a4b86a024f288d7823213
Autor:
Melissa Crabbé, Anke Van der Perren, Ilse Bollaerts, Savannah Kounelis, Veerle Baekelandt, Guy Bormans, Cindy Casteels, Lieve Moons, Koen Van Laere
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The purinergic P2X7 receptor is a key mediator in (neuro)inflammation, a process that is associated with neurodegeneration and excitotoxicity in Parkinson’s disease (PD). Recently, P2X7 imaging has become possible with [11C]JNJ-(54173)717. We inves
Externí odkaz:
https://doaj.org/article/6de7bfdce0b3466c98344755a0281f66
Autor:
Javier María Peralta Ramos, Pablo Iribarren, Luc Bousset, Ronald Melki, Veerle Baekelandt, Anke Van der Perren
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Innate immune activation and chronic neuroinflammation are characteristic features of many neurodegenerative diseases including Parkinson's disease (PD) and may contribute to the pathophysiology of the disease. The discovery of misfolded alpha-synucl
Externí odkaz:
https://doaj.org/article/d6daa41fc71241e2bd5928132fad2c02
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Neurodegenerative diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) impose a pressing burden on our developed and consequently aging society. Misfolded protein aggregates are a critical aspect of several neurodegenerative dis
Externí odkaz:
https://doaj.org/article/f18d7e024b5443bea9b3a59910c1b0af
Autor:
Anke Van der Perren, Chris Van den Haute, Javier M Peralta Ramos, Géraldine Gelders, Veerle Baekelandt, Evy Lobbestael, Diego Cabezudo
Publikováno v:
Neurotherapeutics
The development of disease-modifying therapies for Parkinson’s disease is a major challenge which would be facilitated by a better understanding of the pathogenesis. Leucine-rich repeat kinase 2 (LRRK2) and α-synuclein are key players in Parkinson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50737d58ebbb80b5f23b15aa57f88d39
https://doi.org/10.1007/s13311-021-01007-8
https://doi.org/10.1007/s13311-021-01007-8
Autor:
Teresa Torre-Muruzabal, Anke Van der Perren, Audrey Coens, Géraldine Gelders, Anna Barber Janer, Sara Camacho-Garcia, Therése Klingstedt, Peter Nilsson, Nadia Stefanova, Ronald Melki, Veerle Baekelandt, Wouter Peelaerts
Multiple system atrophy is a progressive neurodegenerative disease with prominent autonomic and motor features. During early stages, different subtypes of the disease are distinguished by their predominant parkinsonian or cerebellar symptoms, reflect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f110be9240c11a501274ecd75729ba
https://lirias.kuleuven.be/handle/20.500.12942/690671
https://lirias.kuleuven.be/handle/20.500.12942/690671
Autor:
Anke Van der Perren, Veerle Baekelandt, Björn H. Falkenburger, Lennart Höfs, Chris Van Den Haute, Eva M. Szegö
Publikováno v:
Experimental neurology 347, 113900 (2022). doi:10.1016/j.expneurol.2021.113900
Experimental neurology 347, 113900 (2022). doi:10.1016/j.expneurol.2021.113900
Published by Elsevier, Amsterdam[u.a.]
Published by Elsevier, Amsterdam[u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b397acfc3516ae9446415578af5ec
Autor:
Michel Koole, Veerle Baekelandt, Anke Van der Perren, Cindy Casteels, Martijn Devrome, Koen Van Laere
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
We investigated the glucose metabolism in an adeno-associated viral vector based alpha-synuclein rat model for Parkinson's disease (PD) using longitudinal 18F-FDG PET imaging, which resulted in an improved characterization of this animal model. We ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443d86a8e2238c3b1a23f387d1789a5f
http://link.springer.com/article/10.1038/s41598-019-48713-0
http://link.springer.com/article/10.1038/s41598-019-48713-0
Autor:
Éva M. Szegõ, Eva M. Szegö, Chris Van den Haute, Lennart Höfs, Veerle Baekelandt, Anke Van der Perren, Björn Falkenburger
BackgroundDuring the pathogenesis of Parkinson’s disease (PD), aggregation of alpha-synuclein (αSyn) induces a vicious cycle of cellular impairments that lead to neurodegeneration. Consequently, removing toxic αSyn aggregates constitutes a plausi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34bccabb3610338904d24cf958eb45a3
https://doi.org/10.21203/rs.3.rs-277472/v1
https://doi.org/10.21203/rs.3.rs-277472/v1
Autor:
Chris Van den Haute, Géraldine Gelders, Anke Van der Perren, Steve M. Gentleman, Alexis Fenyi, Veerle Baekelandt, Wouter Peelaerts, Filipa De Brito, Ronald Melki, Luc Bousset
Publikováno v:
Acta Neuropathologica
Acta Neuropathologica, 2020, ⟨10.1007/s00401-020-02157-3⟩
Acta Neuropathologica, Springer Verlag, 2020, ⟨10.1007/s00401-020-02157-3⟩
Acta Neuropathologica, 2020, ⟨10.1007/s00401-020-02157-3⟩
Acta Neuropathologica, Springer Verlag, 2020, ⟨10.1007/s00401-020-02157-3⟩
Synucleinopathies, such as Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), are defined by the presence of α-synuclein (αSYN) aggregates throughout the nervous system but diverge from one another with re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3f0c5e1de94a6f7f98b39cd567d86
https://cea.hal.science/cea-02561795
https://cea.hal.science/cea-02561795