Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Anke, Leichtle"'
Autor:
Anke Leichtle, Mariia Lupatsii, Simon Graspeuntner, Stephanie Jeschke, Zuzana Penxová, Arwa Kurabi, Allen Frederic Ryan, Jan Rupp, Ralph Pries, Karl-Ludwig Bruchhage
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic Otitis Media (COM) is defined as long term inflammation and colonization with pathogenic bacteria due to a defect or retraction of the tympanic membrane. Surgical interventions are often augmented by antibiotic resistance development
Externí odkaz:
https://doaj.org/article/7b023fd177304e499fcfaca0c5fe3869
Autor:
Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and also have great influenc
Externí odkaz:
https://doaj.org/article/00d90afcd16e4cecbcf18e983b6db96a
Autor:
Claire MacKenzie, Thomas Goerke, Mark Buecking, Mathias Heidemann, Anke Leichtle, Benedikt Ringbeck, Friederike Möllenkolk, Michael Ploch, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disease causing considerable disease burden. The anti-inflammatory monoterpene 1,8-Cineol is a natural plant-based therapeutic agent that is well established to treat
Externí odkaz:
https://doaj.org/article/174a3cf8d38d4496af44c893375bd781
Autor:
Anke Leichtle, Stephanie Jeschke, Kirstin Plötze-Martin, Christian Idel, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 3, p 279 (2024)
Background: Peripheral blood monocytes can be subdivided into different subsets based on the CD14/CD16 surface characteristics. Monocytes are a major source of cytokine secretion of pro-inflammatory immune responses, whereas CD16+ monocyte subsets ca
Externí odkaz:
https://doaj.org/article/1605818c9c474251b87e182c4bedf39a
Autor:
Tamer Soror, Justina Paul, Corinna Melchert, Christian Idel, Dirk Rades, Karl-Ludwig Bruchhage, György Kovács, Anke Leichtle
Publikováno v:
Cancers, Vol 15, Iss 18, p 4549 (2023)
(1) Background: to report on the use of high-dose-rate (HDR) interventional radiotherapy (brachytherapy, IRT) as a salvage treatment for patients with regionally relapsed head and neck cancers. (2) Methods: A retrospective study of 60 patients treate
Externí odkaz:
https://doaj.org/article/86dcb68373ec43ac9f5e1acfc969151c
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Otitis media (OM) is one of the largest public health problems of children and has devastating impacts in developing countries. The substantial medical and human costs involved have led to research to understand the disease and improve treatment. Ani
Externí odkaz:
https://doaj.org/article/8bd559a083244478b2217748ea512e03
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Intracellular nucleotide binding and oligomerization domain (NOD) and Toll-like (TLR) receptors have emerged as pivotal sensors of infection. Both Nod1 and Nod2 contain a caspase activation and recruitment domain (CARD) that interacts with the adapto
Externí odkaz:
https://doaj.org/article/e63e86f4d66d4cee8b15e766331ebd8e
Publikováno v:
Metabolites, Vol 13, Iss 6, p 751 (2023)
The monoterpene 1,8-Cineol is a natural plant-based therapeutic agent that is commonly applied to treat different inflammatory diseases due to its mucolytic, anti-microbial and anti-inflammatory properties. It has become increasingly clear in the rec
Externí odkaz:
https://doaj.org/article/fb2cb82610a14fd197cdbc97a51ae2d7
Autor:
Anke Leichtle, Zuzana Penxova, Thorge Kempin, David Leffers, Martin Ahrens, Peter König, Ralf Brinkmann, Gereon Hüttmann, Karl-Ludwig Bruchhage, Hinnerk Schulz-Hildebrandt
Publikováno v:
Photonics, Vol 10, Iss 6, p 685 (2023)
Hypothesis: Otitis media (OM) can be successfully visualized and diagnosed by dynamic microscopic optical coherence tomography (dmOCT). Background: OM is one of the most common infectious diseases and, according to the WHO, one of the leading health
Externí odkaz:
https://doaj.org/article/6f57a762304c474e9e689fb5d44d0d7d
Autor:
Amelie von Bernuth, Julika Ribbat-Idel, Luise Klapper, Tobias Jagomast, Dirk Rades, Anke Leichtle, Ralph Pries, Karl-Ludwig Bruchhage, Sven Perner, Anne Offermann, Verena Sailer, Christian Idel
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5140 (2023)
Patients with head and neck squamous cell carcinoma (HNSCC) continue to have a rather poor prognosis. Treatment-related comorbidities have negative impacts on their quality of life. TRIM21 is a cytosolic E3 ubiquitin ligase that was initially describ
Externí odkaz:
https://doaj.org/article/d53dda13074743db9b9dc6e14bf6e46b