Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anjum eZafar"'
Autor:
Maria Rosa eLopez-Huertas, Jasmine eLi, Anjum eZafar, Sara eRodriguez-Mora, Carlota eGarcía-Domínguez, Elena eMateos, Jose eAlcami, Sudha eRao, Mayte eCoiras
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
PKCtheta is essential for the activation of CD4+ T cells. Upon TCR/CD28 stimulation, PKCtheta is phosphorylated and migrates to the immunological synapse, inducing the activation of cellular transcription factors such as NF-kB and kinases as ERK that
Externí odkaz:
https://doaj.org/article/a66da0aaa7c44d19b63ab145e5852068
Autor:
Elissa Lee Sutcliffe, Jasmine eLi, Anjum eZafar, Kristine eHardy, Reena eGhildyal, Robert eMcCuaig, Nicole eNorris, Chloe eLim, Peter J Milburn, Marco eCasarotto, Gareth eDenyer, Sudha eRao
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
We recently provided the first description of a nuclear mechanism used by PKC-theta to mediate T cell gene expression. In this mode, PKC-theta tethers to chromatin to form an active nuclear complex by interacting with proteins including RNA polymeras
Externí odkaz:
https://doaj.org/article/b5b3e943130847e58ef82173e5ade376