Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anjli Venkateswaran"'
Autor:
Robert Hodgson, Steven P. Braithwaite, Eliezer Masliah, Barbara Tate, Kimberly Scearce-Levie, Brian K. Kennedy, Anjli Venkateswaran
Publikováno v:
Neurosci Biobehav Rev
Increased healthcare and pharmaceutical understanding has led to the eradication of many childhood, infectious and preventable diseases; however, we are now experiencing the impact of aging disorders as the lifespan increases. These disorders have al
Autor:
Hyunsun Park, Robert Hodgson, Gabrielle G Leblanc, Marc Baumann, Anjli Venkateswaran, John Dunlop, Alexander McCampbell, Judith Frydman, Ron R. Kopito, Antti Nurmi, Patrick Sweeney
Publikováno v:
Translational Neurodegeneration
A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse. Therapeutic options are currently being explored that target different ste
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 89:6168-6172
RET/PTC1, a thyroid-specific oncogene, has been reported to down-regulate sodium/iodide symporter (NIS) expression and function in vitro and in vivo. Recently, RET/PTC1 has been shown to interfere with TSH signaling at multiple levels in thyroid cell
Autor:
Douangsone D. Vadysirisack, Anjli Venkateswaran, Sissy M. Jhiang, Zhaoxia Zhang, Haiyang Tao, Derek K. Marsee, Dale D. Vandre
Publikováno v:
Journal of Biological Chemistry. 279:43990-43997
RET/PTC1 is a rearranged form of the RET tyrosine kinase commonly seen in papillary thyroid carcinomas. It has been shown that RET/PTC1 decreases expression of the sodium/iodide symporter (NIS), the molecule that mediates radioiodide therapy for thyr
Autor:
Charles C. Capen, Bevin Zimmerman, Anjli Venkateswaran, Sissy M. Jhiang, Katherine A.B. Knostman
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 17(12)
RET/PTC1 chromosomal rearrangement is associated with papillary thyroid carcinoma formation in children exposed to ionizing radiation. We previously created a transgenic mouse model with thyroid-targeted constitutive RET/PTC1 expression and demonstra
Publikováno v:
Endocrine-related cancer. 14(2)
The Na+/I− symporter (NIS)-mediated iodide uptake is the basis for targeted radioiodine ablation of thyroid cancers. However, NIS-mediated radioiodide uptake (RAIU) activity is often reduced in thyroid cancers. As mitogen activated protein kinase (
Autor:
Je-Yoel Cho, Krista M. D. La Perle, Marc Lavender, Tara L.F. Buckwalter, Michael L. Robinson, Anjli Venkateswaran, Sissy M. Jhiang
Publikováno v:
Oncogene. 21(53)
RET/PTC1 is a rearranged form of the RET proto-oncogene detected in human papillary thyroid carcinomas. We previously showed that thyroid-targeted expression of RET/PTC1 leads to thyroid tumor formation in Tg-PTC1 transgenic mice. Signal transduction
Autor:
Katherine A.B. Knostman, Anjli Venkateswaran, Bevin Zimmerman, Charles C. Capen, Sissy M. Jhiang
Publikováno v:
Thyroid; Dec2007, Vol. 17 Issue 12, p1181-1188, 8p