Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anjanette P. Harris"'
Autor:
Sofia Kanatsou, Henk Karst, Despoina Kortesidou, Rachelle A. van den Akker, Jan den Blaauwen, Anjanette P. Harris, Jonathan R. Seckl, Harm J. Krugers, Marian Joels
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Evidence from human studies suggests that high expression of brain mineralocorticoid receptors (MR) may promote resilience against negative consequences of stress exposure, including childhood trauma. We examined, in mice, whether brain MR overexpres
Externí odkaz:
https://doaj.org/article/1d39ba41bc8e4ef595882a0c6fdb6e2e
Autor:
Sofia eKanatsou, Laura Esmee Kuil, Marit eArp, Melly S. Oitzl, Anjanette P. Harris, Jonathan R. Seckl, Harm eKrugers, Marian eJoels
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 9 (2015)
Mineralocorticoid receptors (MRs) have been implicated in behavioral adaptation and learning and memory. Since – at least in humans - MR function seems to be sex-dependent, we examined the behavioral relevance of MR in female mice exhibiting transg
Externí odkaz:
https://doaj.org/article/b5c7f730a5394f8ebe455138ce1c5f54
Autor:
Cyril Pernet, Heather C. Whalley, Nichola M. Brydges, Mark Day, Scott J. Baker, Ross J. Lennen, Ian Marshall, Jeremy Hall, Ana M. Basso, Anjanette P. Harris, Maurits A. Jansen, Megan C. Holmes
Publikováno v:
Genes, Brain and Behavior. 15:221-230
Brain-derived neurotrophic factor (BDNF) signaling is implicated in the aetiology of many psychiatric disorders associated with altered emotional processing. Altered peripheral (plasma) BDNF levels have been proposed as a biomarker for neuropsychiatr
Publikováno v:
Genes, brain, and behavior. 18(2)
Major depressive disorder (MDD) is a leading contributor to the global burden of disease. However, the causal relationship of risk factors, such as genetic predisposition or experience of augmented stress, remain unknown. Numerous studies in humans a
Autor:
Nicola, Wheelan, Christopher J, Kenyon, Anjanette P, Harris, Carolynn, Cairns, Emad, Al Dujaili, Jonathan R, Seckl, Joyce L W, Yau
Publikováno v:
Psychoneuroendocrinology
Highlights • Spatial memory deficits after midlife stress remain for 6 months. • Enhanced fear memory and impaired extinction 6 months after midlife stress. • Increased anxiety and depressive-like behaviors 7 months after midlife stress. • 11
Autor:
Maria Emilia Solano, Megan C. Holmes, Anjanette P. Harris, Karen E. Chapman, Clara V. Perani, Petra C. Arck
Publikováno v:
Journal of Reproductive Immunology. 128:58-59
Publikováno v:
Martis, L, Wiborg, O, Holmes, M & Harris, A 2019, ' BDNF+/-rats exhibit depressive phenotype and altered expression of genes relevant in mood disorders ', Genes, Brain and Behavior, vol. 18, no. 2 . https://doi.org/10.1111/gbb.12546
Martis, L-S, Wiborg, O, Holmes, M C & Harris, A P 2019, ' BDNF+/-rats exhibit depressive phenotype and altered expression of genes relevant in mood disorders ', Genes, Brain and Behavior, vol. 18, no. 2, e12546, pp. e12546 . https://doi.org/10.1111/gbb.12546
Martis, L S, Wiborg, O, Holmes, M C & Harris, A P 2019, ' BDNF +/− rats exhibit depressive phenotype and altered expression of genes relevant in mood disorders ', Genes, Brain and Behavior, vol. 18, no. 2, e12546 . https://doi.org/10.1111/gbb.12546
Martis, L-S, Wiborg, O, Holmes, M C & Harris, A P 2019, ' BDNF+/-rats exhibit depressive phenotype and altered expression of genes relevant in mood disorders ', Genes, Brain and Behavior, vol. 18, no. 2, e12546, pp. e12546 . https://doi.org/10.1111/gbb.12546
Martis, L S, Wiborg, O, Holmes, M C & Harris, A P 2019, ' BDNF +/− rats exhibit depressive phenotype and altered expression of genes relevant in mood disorders ', Genes, Brain and Behavior, vol. 18, no. 2, e12546 . https://doi.org/10.1111/gbb.12546
Major depressive disorder (MDD) is a leading contributor to the global burden of disease. However, the causal relationship of risk factors, such as genetic predisposition or experience of augmented stress, remain unknown. Numerous studies in humans a
Autor:
Harmen J. Krugers, Sofia Kanatsou, Jonathan R. Seckl, Marian Joëls, Anjanette P. Harris, Judith P. ter Horst
Publikováno v:
Frontiers in Behavioral Neuroscience, 9:374. Frontiers Media S.A.
Frontiers in Behavioral Neuroscience, Vol 9 (2016)
Frontiers in Behavioral Neuroscience
Kanatsou, S, Ter Horst, J P, Harris, A P, Seckl, J R, Krugers, H J & Joëls, M 2016, ' Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice ', Frontiers in Behavioral Neuroscience, vol. 9, pp. 374 . https://doi.org/10.3389/fnbeh.2015.00374
Frontiers in Behavioral Neuroscience [E], 9(374). Frontiers Research Foundation
Frontiers in Behavioral Neuroscience, Vol 9 (2016)
Frontiers in Behavioral Neuroscience
Kanatsou, S, Ter Horst, J P, Harris, A P, Seckl, J R, Krugers, H J & Joëls, M 2016, ' Effects of Mineralocorticoid Receptor Overexpression on Anxiety and Memory after Early Life Stress in Female Mice ', Frontiers in Behavioral Neuroscience, vol. 9, pp. 374 . https://doi.org/10.3389/fnbeh.2015.00374
Frontiers in Behavioral Neuroscience [E], 9(374). Frontiers Research Foundation
Early-life stress is a risk factor for the development of psychopathology, particularly in women. Human studies have shown that certain haplotypes of NR3C2, encoding the mineralocorticoid receptor (MR), that result in gain of function, may protect ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb4bf6424aa27b5efa53b492cb3e37b
https://dare.uva.nl/personal/pure/en/publications/effects-of-mineralocorticoid-receptor-overexpression-on-anxiety-and-memory-after-early-life-stress-in-female-mice(4996205a-bc23-44f5-9ef5-2d26814fe628).html
https://dare.uva.nl/personal/pure/en/publications/effects-of-mineralocorticoid-receptor-overexpression-on-anxiety-and-memory-after-early-life-stress-in-female-mice(4996205a-bc23-44f5-9ef5-2d26814fe628).html
Autor:
Anjanette P. Harris, Marian Joëls, Harm J. Krugers, Brenna C. Fearey, Sofia Kanatsou, Paul J. Lucassen, Laura E. Kuil, Jonathan R. Seckl
Publikováno v:
PLoS ONE [E], 10(11). Public Library of Science
PLoS ONE, Vol 10, Iss 11, p e0142012 (2015)
PLoS ONE, 10(11):e0142012. Public Library of Science
PLoS ONE
Kanatsou, S, Fearey, B C, Kuil, L E, Lucassen, P J, Harris, A P, Seckl, J R, Krugers, H & Joels, M 2015, ' Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity ', PLoS ONE, vol. 10, no. 11, pp. e0142012 . https://doi.org/10.1371/journal.pone.0142012
PLoS ONE, Vol 10, Iss 11, p e0142012 (2015)
PLoS ONE, 10(11):e0142012. Public Library of Science
PLoS ONE
Kanatsou, S, Fearey, B C, Kuil, L E, Lucassen, P J, Harris, A P, Seckl, J R, Krugers, H & Joels, M 2015, ' Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity ', PLoS ONE, vol. 10, no. 11, pp. e0142012 . https://doi.org/10.1371/journal.pone.0142012
Exposure to chronic stress is a risk factor for cognitive decline and psychopathology in genetically predisposed individuals. Preliminary evidence in humans suggests that mineralocorticoid receptors (MRs) may confer resilience to these stress-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30e5cee3d484e53cb6c7a383b058a63
https://dspace.library.uu.nl/handle/1874/333693
https://dspace.library.uu.nl/handle/1874/333693
Publikováno v:
Animal Behaviour. 77:1459-1464
Rats, Rattus norvegicus, housed with ‘environmental enrichment’ do better in tests of spatial cognition than rats housed in barren cages. The leading hypothesis is that exposure to ‘social and inanimate complexity’ leads to better cognitive-p