Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anjanet Loon"'
Autor:
Ping-Chieh Pao, Jinsoo Seo, Audrey Lee, Oleg Kritskiy, Debasis Patnaik, Jay Penney, Ravikiran M. Raju, Ute Geigenmuller, M. Catarina Silva, Diane E. Lucente, James F. Gusella, Bradford C. Dickerson, Anjanet Loon, Margaret X. Yu, Michael Bula, Melody Yu, Stephen J. Haggarty, Li-Huei Tsai
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Aberrant activity of cyclin-dependent kinase (Cdk5) has been implicated in various neurodegenerative diseases. This deleterious effect is mediated by pathological cleavage of the Cdk5 activator p35 into the truncated product p25, leading to prolonged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f59bcb292e1d1b5c3991d1c46aa356d
https://doi.org/10.1073/pnas.2217864120
https://doi.org/10.1073/pnas.2217864120
Autor:
Jay Penney, William T Ralvenius, Anjanet Loon, Oyku Cerit, Vishnu Dileep, Blerta Milo, Hannah Woolf, Li-Huei Tsai
Genetic findings have highlighted key roles for microglia in the pathology of neurodegenerative conditions such as Alzheimer’s disease (AD). Distinct mutations in the microglial protein TREM2 (triggering receptor expressed on myeloid cells 2) are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404954aebcdc7e3badeb5896e5f148fa
https://doi.org/10.1101/2022.10.05.511003
https://doi.org/10.1101/2022.10.05.511003
