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of 6
pro vyhledávání: '"Anjana Soundararajan"'
Autor:
Katherin Patsch, Naim Matasci, Anjana Soundararajan, Patricia Diaz, David B. Agus, Daniel Ruderman, Mitchell E. Gross
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Cell-free DNA (cfDNA) is an attractive cancer biomarker, as it is thought to reflect a component of the underlying genetic makeup of the tumor and is readily accessible in serial fashion. Because chemotherapy regimens are expected
Externí odkaz:
https://doaj.org/article/b6b28c1fefbe4213905ffdd9b4b4e7d9
Autor:
Patricia M Diaz, Katherin Patsch, Daniel Ruderman, Mitchell E. Gross, Naim Matasci, David B. Agus, Anjana Soundararajan
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
BMC Research Notes
BMC Research Notes
Objective Cell-free DNA (cfDNA) is an attractive cancer biomarker, as it is thought to reflect a component of the underlying genetic makeup of the tumor and is readily accessible in serial fashion. Because chemotherapy regimens are expected to act ra
Autor:
David B. Agus, Scott E. Fraser, Francesco Cutrale, Chi-Li Chiu, Daniel Ruderman, Katherin Patsch, Anjana Soundararajan
Publikováno v:
Scientific Reports
The androgen receptor (AR) pathway plays a central role in prostate cancer (PCa) growth and progression and is a validated therapeutic target. In response to ligand binding AR translocates to the nucleus, though the molecular mechanism is not well un
Autor:
Christina Van Loy, Jonathan P. Katz, Antonio Sanchez, Anjana Soundararajan, Mitchell E. Gross, Zhao Xu, Erika Feierstein, Daniel Ruderman, Katherin Patsch, Naim Matasci, David B. Agus, John Nicoll
Publikováno v:
Cancer Research. 77:3934-3934
Survival rates for patients with muscle-invasive bladder cancer have not improved in the past 20 years, and new therapies are imperative. Intratumor heterogeneity can complicate molecular profiling attempts to optimize therapy for cancers harboring s
Autor:
Daniel Ruderman, Katherin Patsch, Patricia M Diaz, Naim Matasci, Mitchell E. Gross, Anjana Soundararajan
Publikováno v:
Cancer Research. 77:A20-A20
Background: There is great interest in utilizing blood-based circulating biomarkers to gain molecular insight into cancer. Most of the published data examines circulating free DNA (cfDNA) obtained at a single time-point. Here, we developed and utiliz
Abstract A29: Heterogeneity of androgen receptor dynamics and drug response in prostate cancer cells
Autor:
Mark Engeln, Mitchell E. Gross, Anjana Soundararajan, Katherin Patsch, Daniel Ruderman, Shannon M. Mumenthaler
Publikováno v:
Cancer Research. 77:A29-A29
Background: Recent studies suggest that the spatio-temporal dynamics of critical signaling molecules can mediate heterogeneous response to therapeutic intervention. Here, we set out to apply live cell imaging of single cells in high throughput to cor