Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anjan G. Thakurta"'
Autor:
Danny V. Jeyaraju, Maryam Alapa, Ann Polonskaia, Alberto Risueño, Prakash Subramanyam, Amit Anand, Kaushik Ghosh, Charalampos Kyriakopoulos, Daiane Hemerich, Rose Hurren, Xiaoming Wang, Marcela Gronda, Aarif Ahsan, Hsiling Chiu, Geethu Thomas, Evan F. Lind, Daniel L Menezes, Aaron D. Schimmer, Patrick R. Hagner, Anita Gandhi, Anjan G. Thakurta
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Oral azacitidine (oral-Aza) treatment results in longer median overall survival (OS) (24.7 vs. 14.8 months in placebo) in patients with acute myeloid leukemia (AML) in remission after intensive chemotherapy. The dosing schedule of oral-Aza (14 days/2
Externí odkaz:
https://doaj.org/article/1da3b8771381489588b67244fd735638
Publikováno v:
Journal of Biological Chemistry. 282:17507-17516
Mammalian UAP56 or its homolog Sub2p in Saccharomyces cerevisiae are members of the ATP-dependent RNA helicase family and are required for splicing and nuclear export of mRNA. Previously we showed that in Schizosaccharomyces pombe Uap56p is critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1f4987dad904780ca5d2eedac81a1d
https://doi.org/10.1074/jbc.m609727200
https://doi.org/10.1074/jbc.m609727200
Publikováno v:
The EMBO Journal. 24:2512-2523
The breast cancer tumor suppressor BRCA2-interacting protein, DSS1, and its homologs are critical for DNA recombination in eukaryotic cells. We found that Dss1p, along with Mlo3p and Uap56p, Schizosaccharomyces pombe homologs of two messenger RNA (mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c17930896ddf280f74bb9e44fe2c34
https://doi.org/10.1038/sj.emboj.7600713
https://doi.org/10.1038/sj.emboj.7600713
Publikováno v:
Yeast. 19:803-810
Poly(A)-binding proteins play important roles in mRNA metabolism in eukaryotic cells. We examined the role of the Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae poly(A)-binding protein, Pab1p, in cellular growth and mRNA export.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f133b6761b3635b6b82a45090d95e8c8
https://doi.org/10.1002/yea.876
https://doi.org/10.1002/yea.876
Autor:
Ming Zhou, Timothy D. Veenstra, Anjan G. Thakurta, Jothy Dhakshnamoorthy, Saravana P. Selvanathan, Ravi Dhar
Publikováno v:
The Journal of biological chemistry. 285(19)
Schizosaccharomyces pombe Dss1p and its homologs function in multiple cellular processes including recombinational repair of DNA and nuclear export of messenger RNA. We found that Tap-tagged Rad24p, a member of the 14-3-3 class of proteins, co-purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6933d7329841cc18e1efcdfc8ddc36
https://pubmed.ncbi.nlm.nih.gov/20231270
https://pubmed.ncbi.nlm.nih.gov/20231270
Publikováno v:
The Journal of biological chemistry. 279(17)
Mex67, the homolog of human TAP, is not an essential mRNA export factor in Schizosaccharomyces pombe. Here we show that S. pombe encodes a homolog of the TAP cofactor that we have also named p15, whose function in mRNA export is not essential. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdeaf8b1c5e4c2f472f9dff23158b48
https://pubmed.ncbi.nlm.nih.gov/14963046
https://pubmed.ncbi.nlm.nih.gov/14963046
Autor:
Anekella Bharathi, Dona C. Love, Libor Kozak, William Whalen, Anjan G. Thakurta, Craig Whiteford, Ravi Dhar, Jin Ho Yoon, John A. Hanover
Publikováno v:
Molecular biology of the cell. 13(8)
The export of mRNA from the nucleus to the cytoplasm involves interactions of proteins with mRNA and the nuclear pore complex. We isolated Crp79p, a novel mRNA export factor from the same synthetic lethal screen that led to the identification of spMe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9355f5b8c83c57fa43cf1e6ca29ed49
https://pubmed.ncbi.nlm.nih.gov/12181330
https://pubmed.ncbi.nlm.nih.gov/12181330
Autor:
Ravi Dhar, Zuben E. Sauna, Suresh V. Ambudkar, Ganesh Gopal, Libor Kozak, Anjan G. Thakurta, Jin Ho Yoon
Publikováno v:
The Journal of biological chemistry. 277(37)
Rae1p and Mex67p/Tap are conserved mRNA export factors. We have used synthetic lethal genetic screens in Schizosaccharomyces pombe to identify mutations in genes that are functionally linked to rae1 and mex67 in mRNA export. From these screens, we ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db2831cdd8e9a98f0e7f7941d9baa97
https://pubmed.ncbi.nlm.nih.gov/12110682
https://pubmed.ncbi.nlm.nih.gov/12110682