Výsledky vyhledávání - "Anjali Mandlik"

Akademický článek

Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh.

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006399 (2018)

BACKGROUND:The mediators of protection against cholera, a severe dehydrating illness of humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma IgA as well as memory B IgG cells targeting lipopolysaccharide (LPS) of Vibrio

Externí odkaz: https://doaj.org/article/6f09672378c14216a25dae18f6118233

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Akademický článek

A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice.

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003881 (2015)

BACKGROUND:Vibrio cholerae is the cause of cholera, a severe watery diarrhea. Protection against cholera is serogroup specific. Serogroup specificity is defined by the O-specific polysaccharide (OSP) component of lipopolysaccharide (LPS). METHODOLOGY

Externí odkaz: https://doaj.org/article/0e79629c217d48a793da67a0f610ed0b

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Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006399 (2018)

Background The mediators of protection against cholera, a severe dehydrating illness of humans caused by Vibrio cholerae, are unknown. We have previously shown that plasma IgA as well as memory B IgG cells targeting lipopolysaccharide (LPS) of Vibrio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a411dc35e52ef077e5245e112ada22
http://europepmc.org/articles/PMC5912711

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RpoS and quorum sensing control expression and polar localization ofVibrio choleraechemotaxis cluster III proteinsin vitroandin vivo

Autor: Brigid M. Davis, Simon Ringgaard, Matthew K. Waldor, Anjali Mandlik, Troy P. Hubbard

Publikováno v: Molecular Microbiology. 97:660-675

Summary The diarrheal pathogen Vibrio cholerae contains three gene clusters that encode chemotaxis-related proteins, but only cluster II appears to be required for chemotaxis. Here, we present the first characterization of V. cholerae's ‘cluster II

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::feb56b772351f77b77555bae7e5e72cf
https://doi.org/10.1111/mmi.13053

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Comparative RNA-Seq based dissection of the regulatory networks and environmental stimuli underlying Vibrio parahaemolyticus gene expression during infection

Autor: Jonathan Livny, Troy P. Hubbard, Brigid M. Davis, Xiaohui Zhou, Anjali Mandlik, Matthew K. Waldor

Publikováno v: Nucleic Acids Research

Vibrio parahaemolyticus is the leading worldwide cause of seafood-associated gastroenteritis, yet little is known regarding its intraintestinal gene expression or physiology. To date, in vivo analyses have focused on identification and characterizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362a9db9cea055512209670c9b8452ae
http://europepmc.org/articles/PMC4231756

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Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing

Publikováno v: Nature Biotechnology. 30:1232-1239

Single-molecule real-time (SMRT) DNA sequencing allows the systematic detection of chemical modifications such as methylation but has not previously been applied on a genome-wide scale. We used this approach to detect 49,311 putative 6-methyladenine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e588c4fc04eb91000741928e92faa066
https://doi.org/10.1038/nbt.2432

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RNA-Seq-Based Monitoring of Infection-Linked Changes in Vibrio cholerae Gene Expression

Autor: Jonathan Livny, John J. Mekalanos, Jennifer M. Ritchie, William P. Robins, Anjali Mandlik, Matthew K. Waldor

Publikováno v: Cell Host & Microbe. 10:165-174

SummaryPathogens adapt to the host environment by altering their patterns of gene expression. Microarray-based and genetic techniques used to characterize bacterial gene expression during infection are limited in their ability to comprehensively and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185701281c8ef4e8958187e5c33aaecd
https://doi.org/10.1016/j.chom.2011.07.007

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Cell surface display of minor pilin adhesins in the form of a simple heterodimeric assembly in Corynebacterium diphtheriae

Autor: Asis Das, Anjali Mandlik, Hung Ton-That, Chungyu Chang

Publikováno v: Molecular Microbiology. 79:1236-1247

Pilus assembly in Gram-positive bacteria occurs by a two-step mechanism, whereby pilins are polymerized and then covalently anchored to the cell wall. In Corynebacterium diphtheriae, the pilin-specific sortase SrtA catalyses polymerization of the Spa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9f09533875c9ba3034312fa9a891ba2
https://doi.org/10.1111/j.1365-2958.2010.07515.x

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