Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anjali J. Parmar"'
Autor:
Tonya M. Gilbert, Nicole R. Zürcher, Mary C. Catanese, Chieh-En J. Tseng, Maria A. Di Biase, Amanda E. Lyall, Baileigh G. Hightower, Anjali J. Parmar, Anisha Bhanot, Christine J. Wu, Matthew L. Hibert, Minhae Kim, Umar Mahmood, Steven M. Stufflebeam, Frederick A. Schroeder, Changning Wang, Joshua L. Roffman, Daphne J. Holt, Douglas N. Greve, Ofer Pasternak, Marek Kubicki, Hsiao-Ying Wey, Jacob M. Hooker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Gene transcription is known to vary with age and sex, although the underlying mechanisms are unresolved. Here, the authors show that epigenetic enzymes known as HDACs, which regulate gene transcription, are increasingly expressed with age in the livi
Externí odkaz:
https://doaj.org/article/fd891fe0074148ad83476fb18c8b1d21
Autor:
Hannah E. Brown, Changning Wang, Minhae Kim, Jacob M. Hooker, Amy T. Peters, Anjali J. Parmar, Joshua L. Roffman, Baileigh G. Hightower, Tonya M. Gilbert, Nicole R. Zürcher, Roy H. Perlis, Mary C. Catanese, Chieh-En Jane Tseng
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-9 (2020)
Translational Psychiatry
Translational Psychiatry
The etiology of bipolar disorder (BD) is unknown and the neurobiological underpinnings are not fully understood. Both genetic and environmental factors contribute to the risk of BD, which may be linked through epigenetic mechanisms, including those r
Autor:
Anisha Bhanot, David Izquierdo-Garcia, L. Richey, Christopher J. McDougle, Jacob M. Hooker, Chieh-En Jane Tseng, Marco L. Loggia, Jonathan DuBois, Baileigh G. Hightower, Jennifer E Mullett, Christine J. Wu, Daniel B. Chonde, Anjali J. Parmar, Nouchine Hadjikhani, Ciprian Catana, Hsiao-Ying Wey, R. I. Butterfield, Nicole R. Zürcher
Publikováno v:
Molecular Psychiatry. 26:1659-1669
Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD individuals, we measured the in vivo expression of the 18 kDa translocator protein (TSPO), a
Autor:
Jacob M. Hooker, Matthew Louis Hibert, Umar Mahmood, Changning Wang, Joshua L. Roffman, Maria A Di Biase, Nicole R. Zürcher, Minhae Kim, Baileigh G. Hightower, Tonya M. Gilbert, Anisha Bhanot, Amanda E. Lyall, Douglas N. Greve, Ofer Pasternak, Marek Kubicki, Mary C. Catanese, Frederick A. Schroeder, Chieh-En Jane Tseng, Christine J. Wu, Hsiao-Ying Wey, Steven M. Stufflebeam, Anjali J. Parmar, Daphne J. Holt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
Age- and sex-related alterations in gene transcription have been demonstrated, however the underlying mechanisms are unresolved. Neuroepigenetic pathways regulate gene transcription in the brain. Here, we measure in vivo expression of the epigenetic
Publikováno v:
ACS chemical neuroscience. 11(12)
A biomarker, such as protein accumulation as an indicator of disease, can be used to predict disease manifestation, determine intervention, and monitor treatment efficacy. Biomarker development frequently focuses on early detection of disease as this