Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anja vom Hemdt"'
Autor:
Arlen-Celina Lücke, Anja vom Hemdt, Janett Wieseler, Carlo Fischer, Marie Feldmann, Simon Rothenfusser, Jan Felix Drexler, Beate Mareike Kümmerer
Publikováno v:
Viruses, Vol 14, Iss 2, p 346 (2022)
Flavivirus outbreaks require fast and reliable diagnostics that can be easily adapted to newly emerging and re-emerging flaviviruses. Due to the serological cross-reactivity among flavivirus antibodies, neutralization tests (NT) are considered the go
Externí odkaz:
https://doaj.org/article/815533ac903443abaa17141c646a9f71
Publikováno v:
Viruses, Vol 13, Iss 3, p 403 (2021)
Using reverse genetics, we analyzed a chikungunya virus (CHIKV) isolate of the Indian Ocean lineage lacking direct repeat (DR) elements in the 3′ untranslated region, namely DR1a and DR2a. While this deletion mutant CHIKV-∆DR exhibited growth cha
Externí odkaz:
https://doaj.org/article/a5df0832900145f39ffd69ba13dde484
Autor:
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H. Christensen, Yonas M. Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian I. Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate M. Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa E. Müller, Manabu Igarashi, Hiroki Kato
Publikováno v:
Tsukamoto, Y, Hiono, T, Yamada, S, Matsuno, K, Faist, A, Claff, T, Hou, J, Namasivayam, V, vom Hemdt, A, Sugimoto, S, Ng, J Y, Christensen, M H, Tesfamariam, Y M, Wolter, S, Juranek, S, Zillinger, T, Bauer, S, Hirokawa, T, Schmidt, F I, Kochs, G, Shimojima, M, Huang, Y S, Pichlmair, A, Kümmerer, B M, Sakoda, Y, Schlee, M, Brunotte, L, Müller, C E, Igarashi, M & Kato, H 2023, ' Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication ', Science, vol. 379, no. 6632, pp. 586-591 . https://doi.org/10.1126/science.add0875
Orthomyxo- and bunyaviruses steal the 5′ cap portion of host RNAs to prime their own transcription in a process called “cap snatching.” We report that RNA modification of the cap portion by host 2′-O-ribose methyltransferase 1 (MTr1) is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ca613036512c6c980ca13774bda357
https://pure.au.dk/portal/da/publications/inhibition-of-cellular-rna-methyltransferase-abrogates-influenza-virus-capping-and-replication(e57afff0-1209-4d3e-92f4-f592420aad55).html
https://pure.au.dk/portal/da/publications/inhibition-of-cellular-rna-methyltransferase-abrogates-influenza-virus-capping-and-replication(e57afff0-1209-4d3e-92f4-f592420aad55).html
Autor:
Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja vom Hemdt, Jennifer D. Wuerth, Lisa D.J. Schiffelers, Yonas M. Tesfamariam, Florian N. Gohr, Laura Klein, Ines H. Kaltheuner, Stefan Ebner, Dorothee J. Lapp, Jacob Mayer, Jonas Moecking, Hidde L. Ploegh, Eicke Latz, Felix Meissner, Matthias Geyer, Beate M. Kümmerer, Florian I. Schmidt
Publikováno v:
Journal of Experimental Medicine. 220
Inflammasomes integrate cytosolic evidence of infection or damage to mount inflammatory responses. The inflammasome sensor NLRP1 is expressed in human keratinocytes and coordinates inflammation in the skin. We found that diverse stress signals induce
Autor:
Valter Bergant, Shintaro Yamada, Vincent Grass, Yuta Tsukamoto, Teresa Lavacca, Karsten Krey, Maria‐Teresa Mühlhofer, Sabine Wittmann, Armin Ensser, Alexandra Herrmann, Anja vom Hemdt, Yuriko Tomita, Shutoku Matsuyama, Takatsugu Hirokawa, Yiqi Huang, Antonio Piras, Constanze A Jakwerth, Madlen Oelsner, Susanne Thieme, Alexander Graf, Stefan Krebs, Helmut Blum, Beate M Kümmerer, Alexey Stukalov, Carsten B Schmidt‐Weber, Manabu Igarashi, Thomas Gramberg, Andreas Pichlmair, Hiroki Kato
The SARS‐CoV‐2 infection cycle is a multistage process that relies on functional interactions between the host and the pathogen. Here, we repurposed antiviral drugs against both viral and host enzymes to pharmaceutically block methylation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ad981d0b93c9a8add6f05e47e634f2
https://mediatum.ub.tum.de/doc/1689204/document.pdf
https://mediatum.ub.tum.de/doc/1689204/document.pdf
Publikováno v:
Viruses
Viruses, Vol 13, Iss 403, p 403 (2021)
Volume 13
Issue 3
Viruses, Vol 13, Iss 403, p 403 (2021)
Volume 13
Issue 3
Using reverse genetics, we analyzed a chikungunya virus (CHIKV) isolate of the Indian Ocean lineage lacking direct repeat (DR) elements in the 3′ untranslated region, namely DR1a and DR2a. While this deletion mutant CHIKV-∆DR exhibited growth cha