Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Anja Voss-Böhme"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9 (2022)
Understanding the segregation of cells is crucial to answer questions about tissue formation in embryos or tumor progression. Steinberg proposed that separation of cells can be compared to the separation of two liquids. Such a separation is well desc
Externí odkaz:
https://doaj.org/article/3915d13a3b484f6ca0f0c9ad9a803141
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 8, p e1010403 (2022)
Cancer development is a multistep process often starting with a single cell in which a number of epigenetic and genetic alterations have accumulated thus transforming it into a tumor cell. The progeny of such a single benign tumor cell expands in the
Externí odkaz:
https://doaj.org/article/35cb3d4a731f48a399531726699a6444
Autor:
Josué Manik Nava-Sedeño, Haralampos Hatzikirou, Anja Voß-Böhme, Lutz Brusch, Andreas Deutsch, Fernando Peruani
Publikováno v:
New Journal of Physics, Vol 25, Iss 12, p 123046 (2023)
We introduce a novel lattice-gas cellular automaton (LGCA) for compressible vectorial active matter with polar and nematic velocity alignment. Interactions are, by construction, zero-range. For polar alignment, we show the system undergoes a phase tr
Externí odkaz:
https://doaj.org/article/151d6e0936cd4d42919e04969af17b64
Autor:
Anne Dirkse, Anna Golebiewska, Thomas Buder, Petr V. Nazarov, Arnaud Muller, Suresh Poovathingal, Nicolaas H. C. Brons, Sonia Leite, Nicolas Sauvageot, Dzjemma Sarkisjan, Mathieu Seyfrid, Sabrina Fritah, Daniel Stieber, Alessandro Michelucci, Frank Hertel, Christel Herold-Mende, Francisco Azuaje, Alexander Skupin, Rolf Bjerkvig, Andreas Deutsch, Anja Voss-Böhme, Simone P. Niclou
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Cancer stem cells (CSCs) comprise a putative population that can drive growth and resistance. Here, in glioblastoma models the authors show that rather than being a distinct clonal entity, the CSC population represents a plastic state adoptable by mo
Externí odkaz:
https://doaj.org/article/f9953d80d7214efbbab8832d2c810d81
Publikováno v:
Entropy, Vol 23, Iss 11, p 1378 (2021)
The process of cell-sorting is essential for development and maintenance of tissues. Mathematical modeling can provide the means to analyze the consequences of different hypotheses about the underlying mechanisms. With the Differential Adhesion Hypot
Externí odkaz:
https://doaj.org/article/c6859e3500ed40b29cd48d06d128f274
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract During tissue invasion individual tumor cells exhibit two interconvertible migration modes, namely mesenchymal and amoeboid migration. The cellular microenvironment triggers the switch between both modes, thereby allowing adaptation to dynam
Externí odkaz:
https://doaj.org/article/ac30830f1fea4192b35fc976d9691ea0
Publikováno v:
Biology Direct, Vol 12, Iss 1, Pp 1-17 (2017)
Abstract Background Cancer cell invasion, dissemination, and metastasis have been linked to an epithelial-mesenchymal transition (EMT) of individual tumour cells. During EMT, adhesion molecules like E-cadherin are downregulated and the decrease of ce
Externí odkaz:
https://doaj.org/article/0c2c8cf63274408dafebb4375ee74f79
Publikováno v:
Frontiers in Oncology, Vol 8 (2019)
The development of cancer is a multistep process in which cells increase in malignancy through progressive alterations. Such altered cells compete with wild-type cells and have to establish within a tissue in order to induce tumor formation. The rang
Externí odkaz:
https://doaj.org/article/3424f8d49dfe4c9a994034a7e3b4a4d3
Publikováno v:
Bioinformatics and Biology Insights, Vol 11 (2017)
Many normal and cancerous cell lines exhibit a stable composition of cells in distinct states which can, e.g., be defined on the basis of cell surface markers. There is evidence that such an equilibrium is associated with stochastic transitions betwe
Externí odkaz:
https://doaj.org/article/831c0d12364443cfa9160096a191e88a
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004662 (2015)
Pilocytic astrocytoma (PA) is the most common brain tumor in children. This tumor is usually benign and has a good prognosis. Total resection is the treatment of choice and will cure the majority of patients. However, often only partial resection is
Externí odkaz:
https://doaj.org/article/2a19703834904b2fbc094e1ced968023