Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Anja Traeger"'
Autor:
Jonas De Breuck, Michael Streiber, Michael Ringleb, Dennis Schröder, Natascha Herzog, Ulrich S. Schubert, Stefan Zechel, Anja Traeger, Meike N. Leiske
Publikováno v:
ACS Polymers Au, Vol 4, Iss 3, Pp 222-234 (2024)
Externí odkaz:
https://doaj.org/article/c284606bf973411caa6f5296c0407fba
Autor:
Jana I. Solomun, Liam Martin, Prosper Mapfumo, Elisabeth Moek, Elias Amro, Friedrich Becker, Stefan Tuempel, Stephanie Hoeppener, K. Lenhard Rudolph, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Cationic non-viral vectors show great potential to introduce genetic material into cells, due to their ability to transport large amounts of genetic material and their high synthetic versatility. However, designing materials that are effecti
Externí odkaz:
https://doaj.org/article/ac8763d1ebac4c56bbc35c6a64eaf456
Autor:
Friederike Richter, Katharina Leer, Liam Martin, Prosper Mapfumo, Jana I. Solomun, Maren T. Kuchenbrod, Stephanie Hoeppener, Johannes C. Brendel, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Cationic polymers have been widely studied for non-viral gene delivery due to their ability to bind genetic material and to interact with cellular membranes. However, their charged nature carries the risk of increased cytotoxicity and intera
Externí odkaz:
https://doaj.org/article/37aac02f5cbe403ab2958fea85a9a46d
Autor:
Friederike Richter, Prosper Mapfumo, Liam Martin, Jana I. Solomun, Franziska Hausig, Jochen J. Frietsch, Thomas Ernst, Stephanie Hoeppener, Johannes C. Brendel, Anja Traeger
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Although there has been substantial progress in the research field of gene delivery, there are some challenges remaining, e.g. there are still cell types such as primary cells and suspension cells (immune cells) known to be difficult to tran
Externí odkaz:
https://doaj.org/article/83f2b0a9f25f47e8b38855a8890e319d
Autor:
Tobias Kammann, Jessica Hoff, Ilknur Yildirim, Blerina Shkodra, Tina Müller, Christine Weber, Markus H. Gräler, Ulrich A. Maus, James C. Paton, Mervyn Singer, Anja Traeger, Ulrich S. Schubert, Michael Bauer, Adrian T. Press
Publikováno v:
Metabolites, Vol 11, Iss 12, p 821 (2021)
Cholesterol is highly abundant within all human body cells and modulates critical cellular functions related to cellular plasticity, metabolism, and survival. The cholesterol-binding toxin pneumolysin represents an essential virulence factor of Strep
Externí odkaz:
https://doaj.org/article/7862020459c5456abfb67019a7a51292
Autor:
Blerina Shkodra, Adrian T. Press, Antje Vollrath, Ivo Nischang, Stephanie Schubert, Stephanie Hoeppener, Dorothee Haas, Christoph Enzensperger, Marc Lehmann, Petra Babic, Kay Jovana Benecke, Anja Traeger, Michael Bauer, Ulrich S. Schubert
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1110 (2020)
Bisindolylmaleimide I (BIM-I) is a competitive pan protein kinase C inhibitor with anti-inflammatory and anti-metastatic properties, suggested to treat inflammatory diseases and various cancer entities. However, despite its therapeutic potential, BIM
Externí odkaz:
https://doaj.org/article/239eaf11ef024de1bc10c5624c3ffef9
Autor:
Franziska Hausig‐Punke, Gregor Dekevic, Fabian H. Sobotta, Jana I. Solomun, Friederike Richter, Denise Salzig, Anja Traeger, Johannes C. Brendel
Publikováno v:
Macromolecular Bioscience. 23
Autor:
Paul Klemm, Jana I. Solomun, Marko Rodewald, Maren T. Kuchenbrod, Veit G. Hänsch, Friederike Richter, Jürgen Popp, Christian Hertweck, Stephanie Hoeppener, Colin Bonduelle, Sébastien Lecommandoux, Anja Traeger, Stephanie Schubert
Publikováno v:
Biomacromolecules. 23(11)
Within this study, an amphiphilic and potentially biodegradable polypeptide library based on poly[(4-aminobutyl)-l-glutamine
Autor:
Friederike Richter, Franziska Hausig, Anja Traeger, Fabian H. Sobotta, Johannes C. Brendel, Dominic O. Harz
Publikováno v:
ACS Applied Materials & Interfaces. 13:35233-35247
Responsive polymers, which become protonated at decreasing pH, are considered a milestone in the development of synthetic cell entry vectors. Exact correlations between their properties and their ability to escape the endosome, however, often remain
Publikováno v:
Nanoscale. 13:19412-19429
Stimuli-responsive block copolymer micelles can provide tailored properties for the efficient delivery of genetic material. In particular, temperature- and pH-responsive materials are of interest, since their physicochemical properties can be easily