Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Anja Scholzen"'
Autor:
Lilian Driessen-Engels, Roel J Arends, Désirée Damming, Wendela A Kappers, Gijs Verheijden, Mary J van Helden, Ronald C Elgersma, Daphne WJ van Kuppeveld, Dennis Waalboer, Ellen WH Santegoeds-Lenssen, Inge Leenders, Karin de Laat-Arts, Marc CBC Paradé, Menno Winkel, Anja Scholzen, Daniëlle EJW van Wijk, Diels van den Dobbelsteen, Genny Filiciotto, Laura Assink, Myrthe Rouwette, Panagiota I Spantidea, Timo K van den Berg, Wim HA Dokter, Miranda MC van der Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0bdf2e0ad85f4e3c8e9e2cbae21d91f1
Autor:
Susan Raju Paul, Anja Scholzen, Patrick M. Reeves, Robert Shepard, Joshua M. Hess, Richard K. Dzeng, Skylar Korek, Anja Garritsen, Mark C. Poznansky, Ann E. Sluder
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionQ fever, caused by the intracellular bacterium Coxiella burnetii, is considered an occupational and biodefense hazard and can result in debilitating long-term complications. While natural infection and vaccination induce humoral and cellu
Externí odkaz:
https://doaj.org/article/a865dc2f7c6c4ffc86c89c87f974b560
Autor:
Susan Raju Paul, Anja Scholzen, Ghazel Mukhtar, Stephanie Wilkinson, Peter Hobson, Richard K. Dzeng, Jennifer Evans, Jennifer Robson, Rowland Cobbold, Stephen Graves, Mark C. Poznansky, Anja Garritsen, Ann E. Sluder
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Q fever is a zoonotic disease caused by the highly infectious Gram-negative coccobacillus, Coxiella burnetii (C. burnetii). The Q fever vaccine Q-VAX® is characterised by high reactogenicity, requiring individuals to be pre-screened for prior exposu
Externí odkaz:
https://doaj.org/article/8c6d90f2d21149eebb96ec52a13cd52f
Autor:
Ann E. Sluder, Susan Raju Paul, Leonard Moise, Christina Dold, Guilhem Richard, Laura Silva-Reyes, Laurie A. Baeten, Anja Scholzen, Patrick M. Reeves, Andrew J. Pollard, Anja Garritsen, Richard A. Bowen, Anne S. De Groot, Christine Rollier, Mark C. Poznansky
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T cell-mediated immunity plays a central role in the control and clearance of intracellular Coxiella burnetii infection, which can cause Q fever. Therefore, we aimed to develop a novel T cell-targeted vaccine that induces pathogen-specific cell-media
Externí odkaz:
https://doaj.org/article/0a5ff63337eb4ed29ed7e0c1c90e73b2
Autor:
Anja Scholzen, Margot de Vries, Hans-Peter Duerr, Hendrik-Jan Roest, Ann E. Sluder, Mark C. Poznansky, Milou L. C. E. Kouwijzer, Anja Garritsen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
For the zoonotic disease Q fever, serological analysis plays a dominant role in the diagnosis of Coxiella burnetii infection and in pre-screening for past exposure prior to vaccination. A number of studies suggest that assessment of C. burnetii-speci
Externí odkaz:
https://doaj.org/article/a5b0d4ee1bb94f2fa47600445d302a25
Autor:
Jona Walk, Isaie J. Reuling, Marije C. Behet, Lisette Meerstein-Kessel, Wouter Graumans, Geert-Jan van Gemert, Rianne Siebelink-Stoter, Marga van de Vegte-Bolmer, Thorsten Janssen, Karina Teelen, Johannes H. W. de Wilt, Quirijn de Mast, André J. van der Ven, Ernest Diez Benavente, Susana Campino, Taane G. Clark, Martijn A. Huynen, Cornelus C. Hermsen, Else M. Bijker, Anja Scholzen, Robert W. Sauerwein
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-12 (2017)
Abstract Background A highly efficacious vaccine is needed for malaria control and eradication. Immunization with Plasmodium falciparum NF54 parasites under chemoprophylaxis (chemoprophylaxis and sporozoite (CPS)-immunization) induces the most effici
Externí odkaz:
https://doaj.org/article/eee27ea92d754028b1c1673d7a92f598
Autor:
Joshua M. Obiero, Joseph J. Campo, Anja Scholzen, Arlo Randall, Else M. Bijker, Meta Roestenberg, Cornelus C. Hermsen, Andy Teng, Aarti Jain, D. Huw Davies, Robert W. Sauerwein, Philip L. Felgner
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
ABSTRACT Immunization with sporozoites under chloroquine chemoprophylaxis (CPS) induces distinctly preerythrocytic and long-lasting sterile protection against homologous controlled human malaria infection (CHMI). To identify possible humoral immune c
Externí odkaz:
https://doaj.org/article/8e165887dd384f20b347b911c8b738d8
Autor:
Anja Scholzen, Guilhem Richard, Leonard Moise, Laurie A. Baeten, Patrick M. Reeves, William D. Martin, Timothy A. Brauns, Christine M. Boyle, Susan Raju Paul, Richard Bucala, Richard A. Bowen, Anja Garritsen, Anne S. De Groot, Ann E. Sluder, Mark C. Poznansky
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Coxiella burnetii, the causative agent of Q fever, is a Gram-negative intracellular bacterium transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine Q-VAX® in the US and Europe is hindered by reactogenicity in previously e
Externí odkaz:
https://doaj.org/article/8f3d7cea8fe147daa18cf4076819e78a
Autor:
Remko Schats, Else M Bijker, Geert-Jan van Gemert, Wouter Graumans, Marga van de Vegte-Bolmer, Lisette van Lieshout, Mariëlle C Haks, Cornelus C Hermsen, Anja Scholzen, Leo G Visser, Robert W Sauerwein
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124243 (2015)
Sterile protection in >90% of volunteers against homologous Plasmodium falciparum infection has been achieved only using the controlled human malaria infection (CHMI) model. This efficient model involves whole parasite immunizations under chloroquine
Externí odkaz:
https://doaj.org/article/36b0b6485f19473babe0d127b780607a
Autor:
Rachael J Borg, Andre L Samson, Amanda E-L Au, Anja Scholzen, Martina Fuchsberger, Ying Y Kong, Roxann Freeman, Nicole A Mifsud, Magdalena Plebanski, Robert L Medcalf
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131216 (2015)
Removal of dead cells in the absence of concomitant immune stimulation is essential for tissue homeostasis. We recently identified an injury-induced protein misfolding event that orchestrates the plasmin-dependent proteolytic degradation of necrotic
Externí odkaz:
https://doaj.org/article/74a3e5619761464eb29d3d0f75050cfb