Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anja Schöpflin"'
Autor:
Anja Schöpflin, Daniela Batarello, Dieter Hauschke, Corinna Herz, Martin Werner, Christiane D. Fichter, Fabienne Schlurmann, Silke Lassmann, Claudia Münch
Publikováno v:
Molecular Carcinogenesis. 51:696-710
Aurora A “over-”expression may induce supernumerary centrosomes, respective multipolar mitoses, and aneuploidy. Here, we examined Aurora A positive multipolar mitoses in aneuploid, microsatellite-stable (MSS, “CIN-type”) versus near-diploid,
Autor:
Christiane Daniela, Fichter, Sylvia, Timme, Julia Alexandra, Braun, Verena, Gudernatsch, Anja, Schöpflin, Lioudmilla, Bogatyreva, Helene, Geddert, Gerhard, Faller, David, Klimstra, Laura, Tang, Dieter, Hauschke, Martin, Werner, Silke, Lassmann
Publikováno v:
International journal of cancer. 135(7)
Receptor tyrosine kinases (RTKs) are in the focus of targeted therapy for epithelial tumors. Our study addressed the role of EGFR, HER2 and HER3 expression and dimerization in esophageal cancers in situ and in vitro in the context of therapeutic EGFR
Autor:
Ilona Kohler, Melanie Boerries, Laura H. Tang, S Ihde, K Atanasov, Dieter Hauschke, Christiane D. Fichter, Anja Schöpflin, David S. Klimstra, Lioudmila Bogatyreva, Martin Werner, Helene Geddert, Sylvia Timme, Thomas Reinheckel, Silke Lassmann, Gerhard Faller, Hauke Busch, V Waehle
Publikováno v:
Oncogene. 33(25)
Signal transducer and activator of transcription 3 (STAT3) is altered in several epithelial cancers and represents a potential therapeutic target. Here, STAT3 expression, activity and cellular functions were examined in two main histotypes of esophag
Publikováno v:
Epigenetics. 6(5)
Aberrant Wnt/β-catenin signaling is a driving force during initiation and progression of colorectal cancer. Yet, the Wnt/β-catenin targets CDX1, EPHB2, EPHB3 and EPHB4 (EPHB2-4) act as tumor suppressors in intestinal epithelial cells and frequently
Autor:
Robert Zeiser, Cornelius F. Waller, Tilman Brummer, Annette M. May, Konrad Aumann, Franziska U. Wöhrle, Martin Werner, Silke Lassmann, Dieter Hauschke, Anja Schöpflin
Publikováno v:
Human pathology. 42(5)
Grb2-associated binder 2 protein (Gab2) is a member of scaffold proteins, playing crucial roles in (receptor-) tyrosine kinase and cytokine signaling. Chronic myeloid leukemia cells with t(9;22)(q34;q11) express the Bcr/Abl fusion protein, which inte
Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer
Autor:
Emna Sakka, Yuko Shimizu, Axel zur Hausen, Mario Sarbia, Martin Werner, Anja Schöpflin, Tadamasa Ooka, Elisabeth Nikolopoulos, Timo Heidt, Thorsten Wiech, Silke Lassman
Publikováno v:
Virchows Archiv : an international journal of pathology. 452(6)
Approximately 10% of gastric carcinomas (GC) worldwide are associated with Epstein–Barr virus (EBV). GC is one of the most frequent human malignancies associated with EBV. The latent expression of the EBV-oncogene BARF1 is restricted to epithelial
Autor:
Silke Lassmann, Jinru Shia, Anja Schöpflin, Marinela Capanu, Mithat Gonen, Laura H. Tang, Thomas Brabletz, Nancy E. Kemeny, David S. Klimstra, Axel zur Hausen, Martin Werner
Publikováno v:
Gastroenterology. 133(6)
The aims of the study were to evaluate the predictive value of 8 candidate molecular markers for colorectal cancer (CRC) patients receiving hepatic arterial infusion (floxuridine [FUDR] and dexamethasone) and systemic irinotecan (CPT11) post resectio
Autor:
Thorsten Wiech, Elisabeth Nikolopoulos, Silke Lassman, Timo Heidt, Anja Schöpflin, Martin Werner, Emna Sakka, Tadamasa Ooka, Axel zur Hausen, Wiech, Thorsten, Nikolopoulos, Elisabeth, Lassman, Silke, Heidt, Timo, Schöpflin, Anja, Sarbia, Mario, Werner, Martin, Shimizu, Yuko, Sakka, Emna, Ooka, Tadamasa, zur Hausen, Axel
Publikováno v:
Virchows Archiv: European Journal of Pathology; Jun2008, Vol. 452 Issue 6, p621-627, 7p