Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anja Rockstroh"'
Autor:
Charles L. Bidgood, Lisa K. Philp, Anja Rockstroh, Melanie Lehman, Colleen C. Nelson, Martin C. Sadowski, Jennifer H. Gunter
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-12 (2024)
Abstract Metabolic reprogramming and energetic rewiring are hallmarks of cancer that fuel disease progression and facilitate therapy evasion. The remodelling of oxidative phosphorylation and enhanced lipogenesis have previously been characterised as
Externí odkaz:
https://doaj.org/article/5811d1732bff4d279de2e125b6da8d03
Autor:
Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O'Byrne, Ana Clara Simoes Florido Almeida, Patricia Zadorosnei Rebutini, Cleber Machado‐Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia deNoronha, Ruby Huang, Gabrielle T Belz, Fernando Souza‐Fonseca‐Guimaraes, Vicki Clifton, Arutha Kulasinghe
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 2, Pp n/a-n/a (2024)
Abstract Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a ‘preeclampsia‐like syndrome’. Howe
Externí odkaz:
https://doaj.org/article/c26444dbfdab4c58aeeef3df629fe26a
Autor:
Smriti Chawla, Anja Rockstroh, Melanie Lehman, Ellca Ratther, Atishay Jain, Anuneet Anand, Apoorva Gupta, Namrata Bhattacharya, Sarita Poonia, Priyadarshini Rai, Nirjhar Das, Angshul Majumdar, Jayadeva, Gaurav Ahuja, Brett G. Hollier, Colleen C. Nelson, Debarka Sengupta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Predicting treatment response in cancer remains a highly complex task. Here, the authors develop Precily, a deep neural network framework to predict treatment response in cancer by considering gene expression, pathway activity estimates and drug feat
Externí odkaz:
https://doaj.org/article/02a9dee061714a6ca6f4b672374147c3
Autor:
Yu Hin Tang, Anja Rockstroh, Kamil A. Sokolowski, Layla-Rose Lynam, Melanie Lehman, Erik W. Thompson, Philip A. Gregory, Colleen C. Nelson, Marianna Volpert, Brett G. Hollier
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Background Triple-negative breast cancers (TNBC) have a relatively poor prognosis and responses to targeted therapies. Between 25 and 39% of TNBCs are claudin-low, a poorly differentiated subtype enriched for mesenchymal, stem cell and mitog
Externí odkaz:
https://doaj.org/article/684155e1b55647e9a6a13d4ab5bc7d5f
Therapy-induced lipid uptake and remodeling underpin ferroptosis hypersensitivity in prostate cancer
Autor:
Kaylyn D. Tousignant, Anja Rockstroh, Berwyck L. J. Poad, Ali Talebi, Reuben S. E. Young, Atefeh Taherian Fard, Rajesh Gupta, Tuo Zang, Chenwei Wang, Melanie L. Lehman, Johan V. Swinnen, Stephen J. Blanksby, Colleen C. Nelson, Martin C. Sadowski
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-21 (2020)
Abstract Background Metabolic reprograming, non-mutational epigenetic changes, increased cell plasticity, and multidrug tolerance are early hallmarks of therapy resistance in cancer. In this temporary, therapy-tolerant state, cancer cells are highly
Externí odkaz:
https://doaj.org/article/c6e2a3ea96274cda8079bc82f329c973
Autor:
Thomas Kryza, Nathalie Bock, Scott Lovell, Anja Rockstroh, Melanie L. Lehman, Adam Lesner, Janaththani Panchadsaram, Lakmali Munasinghage Silva, Srilakshmi Srinivasan, Cameron E. Snell, Elizabeth D. Williams, Ladan Fazli, Martin Gleave, Jyotsna Batra, Colleen Nelson, Edward W. Tate, Jonathan Harris, John D. Hooper, Judith A. Clements
Publikováno v:
Molecular Oncology, Vol 14, Iss 1, Pp 105-128 (2020)
Kallikrein‐related peptidase 14 (KLK14) is one of the several secreted KLK serine proteases involved in prostate cancer (PCa) pathogenesis. While relatively understudied, recent reports have identified KLK14 as overexpressed during PCa development.
Externí odkaz:
https://doaj.org/article/d544b520f038431180fefe9421c7d971
Autor:
Colleen C. Nelson, Rohan A. Davis, Melanie Lehman, Maria Kavallaris, Brian Gabrielli, Anja Rockstroh, Martin C. Sadowski, Claire Levrier
HeLa-H2B-GFP cells were imaged using an Olympus IX81 (1 image/5 min for 24 h). Top panels: brightfield, bottom panels: GFP channel. 6-AA increased in a concentration-dependent manner mitotic duration, leading to cell death or asymmetric division. Sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d089ae51ff6dd3909643e653283b08c
https://doi.org/10.1158/1535-7163.22507932.v1
https://doi.org/10.1158/1535-7163.22507932.v1
Autor:
Colleen C. Nelson, Rohan A. Davis, Melanie Lehman, Maria Kavallaris, Brian Gabrielli, Anja Rockstroh, Martin C. Sadowski, Claire Levrier
EB1-GFP was imaged by spinning disk microscopy (2 images/s for 2 min). EB1 comets appeared faint and followed irregular and short trajectories. Scale bar=10 µm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831c7ac11f465fe682aaac0aaecaff4e
https://doi.org/10.1158/1535-7163.22507923.v1
https://doi.org/10.1158/1535-7163.22507923.v1
Autor:
Colleen C. Nelson, Rohan A. Davis, Melanie Lehman, Maria Kavallaris, Brian Gabrielli, Anja Rockstroh, Martin C. Sadowski, Claire Levrier
Supplementary Figures S1â^'S9 and figures legends Supplementary Tables S1â^'S6 Supplementary Videos S1â^'S5 and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf5328b8195e9be81dedc8f9b779729
https://doi.org/10.1158/1535-7163.22507938.v1
https://doi.org/10.1158/1535-7163.22507938.v1
Autor:
Martin C. Sadowski, Colleen C. Nelson, Marcel E. Dinger, Nenad Bartonicek, Lisa K. Philp, Stephen J. McPherson, Chenwei Wang, Melanie L. Lehman, Atefeh Taherian Fard, Anja Rockstroh, Kaylyn D. Tousignant
Figure S1: LNCaP, VCaP and DuCaP cells were grown in charcoal-dextran stripped serum (CSS) for 48 h and treated with increasing concentrations of R1881 or DHT in the presence or absence of Enzalutamide (10 µM) or vehicle (Ctrl) for 48 h. Figure S2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110d167333fec1a49913df2360f93a80
https://doi.org/10.1158/1541-7786.22513437.v1
https://doi.org/10.1158/1541-7786.22513437.v1