Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Anja Ramstedt Jensen"'
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Akademický článek
Cerebral malaria – modelling interactions at the blood–brain barrier in vitro
Autor: Yvonne Adams, Anja Ramstedt Jensen
Publikováno v: Disease Models & Mechanisms, Vol 15, Iss 7 (2022)
The blood–brain barrier (BBB) is a continuous endothelial barrier that is supported by pericytes and astrocytes and regulates the passage of solutes between the bloodstream and the brain. This structure is called the neurovascular unit and serves t
Externí odkaz: https://doaj.org/article/bc289b82c3834ec99f2e28a33afb6e75
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2
Chip-Based Assay of Adhesion of Plasmodium falciparum-Infected Erythrocytes to Cells Under Flow
Autor: Yvonne, Adams, Anja Ramstedt, Jensen
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2470
Unique to Plasmodium falciparum malaria parasites, the mature asexual stages of the life cycle are absent from the peripheral blood stream. Using syringe pumps and commercially available microslides, it is possible to mimic the blood flow, and invest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b3ea722042189137460b554471ef7e0
https://pubmed.ncbi.nlm.nih.gov/35881374
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3
Receptor Affinity-Based Purification of PfEMP1 Proteins
Autor: Rebecca W, Olsen, Jennifer, Suurbaar, Anja Ramstedt, Jensen
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2470
The virulence of Plasmodium falciparum is linked to the ability of infected erythrocytes (IEs) to bind a range of human receptors. This binding is mediated by a family of highly polymorphic proteins known as P. falciparum erythrocyte membrane protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a2f60f140af26f999cca828bb3ae357
https://pubmed.ncbi.nlm.nih.gov/35881354
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4
Affinity Purification of PfEMP1-Specific Antibodies from Human Blood
Autor: Rebecca W, Olsen, Jennifer, Suurbaar, Anja Ramstedt, Jensen
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2470
Acquired immunity against Plasmodium falciparum infections relies heavily on IgG antibodies specific for PfEMP1 proteins expressed on the surface of infected erythrocytes. Purified human antibodies can be used, for example, to study the interactions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7567e0fd786053524ee8aaa71997915a
https://pubmed.ncbi.nlm.nih.gov/35881359
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5
Production of anti-PfEMP1 Polyclonal Antisera in Rats and Mice
Autor: Rebecca W, Olsen, Jennifer, Suurbaar, Anja Ramstedt, Jensen
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2470
Plasmodium falciparum-infected erythrocytes (IEs) bind various host receptors via members of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family expressed on the surface of the IEs. Antibody reagents are needed to investigate interaction
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04d675044485be9336be363db5076845
https://pubmed.ncbi.nlm.nih.gov/35881360
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6
3D Organoid Assay of the Impact of Infected Erythrocyte Adhesion on the Blood-Brain Barrier
Autor: Yvonne, Adams, Anja Ramstedt, Jensen
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2470
Mass sequestration of Plasmodium falciparum parasites in the brain microvasculature can lead to cerebral malaria (CM), characterized by inflammation, vessel occlusion, and brain swelling. To date, only single-cell-type, monolayer assays have been use
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9892b14bb28d042ee362ea0a89bdd01e
https://pubmed.ncbi.nlm.nih.gov/35881376
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7
Cerebral malaria - modelling interactions at the blood-brain barrier in vitro
Autor: Anja Ramstedt Jensen, Yvonne Adams
Publikováno v: Adams, Y & Jensen, A R 2022, ' Cerebral malaria-modelling interactions at the blood-brain barrier in vitro ', Disease models & mechanisms, vol. 15, no. 7, dmm049410 . https://doi.org/10.1242/dmm.049410
The blood–brain barrier (BBB) is a continuous endothelial barrier that is supported by pericytes and astrocytes and regulates the passage of solutes between the bloodstream and the brain. This structure is called the neurovascular unit and serves t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c2574f3cebc5e11d7eb2ac19f57115
https://pubmed.ncbi.nlm.nih.gov/35815443
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8
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria
Autor: Tamir Zelter, Jacob Strahilevitz, Karina Simantov, Olga Yajuk, Yvonne Adams, Anja Ramstedt Jensen, Ron Dzikowski, Zvi Granot
Publikováno v: Zelter, T, Strahilevitz, J, Simantov, K, Yajuk, O, Adams, Y, Ramstedt Jensen, A, Dzikowski, R & Granot, Z 2022, ' Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria ', EMBO Reports, vol. 23, e53641 . https://doi.org/10.15252/embr.202153641
Plasmodium falciparum, the deadliest form of human malaria, remains one of the major threats to human health in endemic regions. Its virulence is attributed to its ability to modify infected red blood cells (iRBC) to adhere to endothelial receptors b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203f47ba252851031c1d8ab823274409
https://doi.org/10.15252/embr.202153641
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