Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anja R. Scholze"'
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110668 (2014)
Astrocytes constitute a major cell population in the brain with a myriad of essential functions, yet we know remarkably little about the signaling pathways and mechanisms that direct astrocyte maturation. To explore the signals regulating astrocyte d
Externí odkaz:
https://doaj.org/article/83831324e84c492e8ede14f5634c888d
Autor:
Lauren Westendorf, Anna Loparev, Jennifer Cho, Anja R. Scholze, Orit Shaer, Margaret Flemings, Romie Littrell
Publikováno v:
Tangible and Embedded Interaction
We present BacPack, a tangible museum exhibit for exploring bio-design. BacPack utilizes tangible tokens on a large multitouch table display to allow visitors the opportunity to participate in a playful bio-design activity-engineering bacteria for su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f18f7086dbf37da04c23eece4a8de52a
https://doi.org/10.1145/3024969.3025000
https://doi.org/10.1145/3024969.3025000
Autor:
Jian Qian Wu, Steven A. Sloan, Shuyun Deng, Chaolin Zhang, Ye Zhang, Tom Maniatis, Christine Caneda, Hemali Phatnani, Shane A. Liddelow, Richard Daneman, Nadine Ruderisch, Anja R. Scholze, Ben A. Barres, Sean O'Keeffe, Paolo Guarnieri, Mariko L. Bennett, Kenian Chen
Publikováno v:
The Journal of Neuroscience. 34:11929-11947
The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc58594e8d805b4ea109c8f8790d10e
https://doi.org/10.1523/jneurosci.1860-14.2014
https://doi.org/10.1523/jneurosci.1860-14.2014
Autor:
Romie Littrell, Orit Shaer, Lauren Westendorf, Casey Grote, Evan Segreto, Anja R. Scholze, Johanna Okerlund
Publikováno v:
Tangible and Embedded Interaction
We present SynFlo, a tangible museum exhibit for exploring bio-design. SynFlo utilizes active and concrete tangible tokens to allow visitors to experience a playful biodesign activity through complex interactivity with digital biological creations. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753d0238abc60065a10592cc3dc174b0
https://doi.org/10.1145/2839462.2839488
https://doi.org/10.1145/2839462.2839488
Autor:
Trent A. Watkins, Anja R. Scholze
Publikováno v:
Cold Spring Harbor protocols. 2014(10)
This protocol describes the generation of a rapidly myelinating central nervous system coculture for the study of complex neuronal-glial interactions in vitro. Postnatal rat retinal ganglion cells (RGCs) purified by immunopanning are promoted to clus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94bf94f8759324fbae1f6fa288d6d0b
https://pubmed.ncbi.nlm.nih.gov/25275100
https://pubmed.ncbi.nlm.nih.gov/25275100
Autor:
Anja R. Scholze, Trent A. Watkins
Publikováno v:
Cold Spring Harbor protocols. 2014(10)
In this article, we introduce methods for generating rapidly myelinating cocultures with reaggregates of purified retinal ganglion cells and optic nerve oligodendrocyte precursor cells. This coculture system facilitates the study of complex central n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff6620a7191e711ac67eb864b07217d
https://pubmed.ncbi.nlm.nih.gov/25275113
https://pubmed.ncbi.nlm.nih.gov/25275113
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110668 (2014)
PLoS ONE
PLoS ONE
Astrocytes constitute a major cell population in the brain with a myriad of essential functions, yet we know remarkably little about the signaling pathways and mechanisms that direct astrocyte maturation. To explore the signals regulating astrocyte d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9df8ab1c0147e3fa5ae670b03ebcbbb
http://europepmc.org/articles/PMC4201562?pdf=render
http://europepmc.org/articles/PMC4201562?pdf=render
Autor:
Ben A. Barres, Anja R. Scholze
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(4)
A requisite component of nervous system development is the achievement of cellular recognition and spatial segregation through competition-based refinement mechanisms. Competition for available axon space by myelinating oligodendrocytes ensures that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba3934afa82db361ff935a6374b0d38
https://pubmed.ncbi.nlm.nih.gov/22160722
https://pubmed.ncbi.nlm.nih.gov/22160722
Autor:
Ben Emery, Anja R. Scholze, Brandon Ason, Ben A. Barres, Jason C. Dugas, Lynette C. Foo, Trinna L. Cuellar, Jennifer L. Zamanian, Michael T. McManus, Adiljan Ibrahim
Summary To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and myelination, we utilized transgenic mice in which microRNA processing was disrupted in OL precursor cells (OPCs) and OLs by targeted deletion of Dicer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f6cec04237a31654dd880398c8d608
https://europepmc.org/articles/PMC2843397/
https://europepmc.org/articles/PMC2843397/
Publikováno v:
Lyons, D A, Naylor, S G, Scholze, A & Talbot, W S 2009, ' Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons ', Nature Genetics, vol. 41, no. 7, pp. 854-858 . https://doi.org/10.1038/ng.376
Nature genetics
Nature genetics
The kinesin motor protein Kif1b has previously been implicated in the axonal transport of mitochondria and synaptic vesicles1,2. More recently kif1b has been linked with susceptibility to Multiple Sclerosis (MS) 3. Here we show that Kif1b is required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b4dd9cd555443fee52ae13f9a89b3c
https://www.pure.ed.ac.uk/ws/files/8310958/Kif1b_is_essential_for_mRNA_localization_in_oligodendrocytes_and_development_of_myelinated_axons.pdf
https://www.pure.ed.ac.uk/ws/files/8310958/Kif1b_is_essential_for_mRNA_localization_in_oligodendrocytes_and_development_of_myelinated_axons.pdf