Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anja Nussher"'
Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies
Autor:
Francois Pognan, Min Dong, Armin Wolf, Ursula Junker, Jeffrey Tsao, David Ledieu, Ulrich W. Laengle, Danielle Roman, Anja Nussher, Olivier Grenet, Christian Trendelenburg, Gilles-Jacques Riviere, Philippe Couttet, Estelle Marrer, Elke Persohn, Marcia Heron, Daniel Robert Roth
Publikováno v:
Leukemia Research. 34:1180-1188
Cytotoxic concentrations of imatinib mesylate (10–50 μM) were required to trigger markers of apoptosis and endoplasmic reticulum stress response in neonatal rat ventricular myocytes and fibroblasts, with no significant differences observed between
Autor:
Corinna E. Rüfer, Diana Fridrich, Sandra Vatter, Anja Nussher, S. Skrbek, Julia Reichert, Doris Marko, Gudrun Pahlke, Sabine Hofem, Melanie Kern
Publikováno v:
Molecular Nutrition & Food Research. 51:1163-1172
In the present study we investigated the stability of anthocyanidins under cell culture conditions and addressed the question whether degradation products might contribute to the cellular effects assigned to the parent compounds. Substantial degradat