Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anja Mehl"'
Publikováno v:
Journal of Virology. 75:9129-9141
The latent membrane protein 1 (LMP-1) oncogene of Epstein-Barr virus (EBV) is believed to contribute to the development of many EBV-associated tumors, and there is evidence that sequence variation can affect some functions of LMP-1. Most studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab5cde5e0ab174eba18846f0320e648
https://doi.org/10.1128/jvi.75.19.9129-9141.2001
https://doi.org/10.1128/jvi.75.19.9129-9141.2001
Autor:
Eun Young Choi, Martin Rowe, Im-Soon Lee, Minchan Gil, Kyeong Cheon Jung, Min-Kyung Kim, Anja Mehl, Seong Hoe Park
Publikováno v:
Blood. 97:3596-3604
Epstein-Barr virus (EBV)-encoded latent membrane protein-1 (LMP1) is highly expressed in Hodgkin and Reed-Sternberg (H-RS) cells from patients with EBV-associated Hodgkin disease. It was previously demonstrated that CD99 can be negatively regulated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33c40c860914e07e02ea4dd137acaa3
https://doi.org/10.1182/blood.v97.11.3596
https://doi.org/10.1182/blood.v97.11.3596
Publikováno v:
Journal of Biological Chemistry. 276:984-992
The latent membrane protein-1 (LMP1) of Epstein-Barr virus induces gene transcription, phenotypic changes, and oncogenic transformation. One cellular gene induced by LMP1 is that for intercellular adhesion molecule-1 (ICAM-1), which participates in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c478a5e0b02463862856e166d5f2907
https://doi.org/10.1074/jbc.m003758200
https://doi.org/10.1074/jbc.m003758200
Autor:
Michael Pfreundschuh, Heiner Daus, Nicole Fischer, Lorenz Trümper, Friedrich A. Grässer, Anja Mehl, Frank Hartmann, Martin Rowe, Nikolaus Muller-Lantzsch
Publikováno v:
International Journal of Cancer. 76:194-200
Two genes encoding the latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV) were isolated from a single case of Hodgkin's disease (HD) and were tested for their biological activities. The LMP1 gene from the Reed-Sternberg cells contained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b743290af035686fef01cd1298d5066a
https://doi.org/10.1002/(sici)1097-0215(19980413)76:2<194::aid-ijc5>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19980413)76:2<194::aid-ijc5>3.0.co
Autor:
Dermot Walls, Ann Clarke, Sinéad T. Loughran, Brendan N. D'Souza, Sinead M. Smith, Leonard C. Edelstein, Pamela M. Pegman, Martin Rowe, Céline Gélinas, Anja Mehl
Suppression of the cellular apoptotic program by the oncogenic herpesvirus Epstein-Barr virus (EBV) is central to both the establishment of latent infection and the development of EBV-associated malignancies. We have previously shown that expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d712f8dfcde464db6ad5f7dea0b7ca6
https://europepmc.org/articles/PMC369510/
https://europepmc.org/articles/PMC369510/
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 167(11)
CD40 is an important mediator of immune and inflammatory responses. It is a costimulatory molecule for B cell proliferation and survival. Blockade of CD40 has been shown to induce tolerance and its role in other pathogenic conditions has led to the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb256e88419a05db9eddedb98b2fc8d0
https://pubmed.ncbi.nlm.nih.gov/11714804
https://pubmed.ncbi.nlm.nih.gov/11714804
Publikováno v:
Oncogene. 21(8)
B-cell lymphoma, which is increasing world wide, includes such varied conditions as post-transplant lymphoproliferative disease (PTLD) and Burkitt's lymphoma. This study has characterized a role for the signalling molecule phosphatidylinositol 3-kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39aac1c03ee8fcb3120865ea4f029ed8
https://pubmed.ncbi.nlm.nih.gov/11850846
https://pubmed.ncbi.nlm.nih.gov/11850846
Publikováno v:
The Journal of biological chemistry. 276(2)
Latent membrane protein-1 (LMP1) is a signaling molecule expressed by Epstein-Barr virus during latency. LMP1 is essential for B-cell immortalization by Epstein-Barr virus and transforms rodent fibroblasts. It activates many distinct signaling pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fe3924324258e6a153fb57416429c7
https://pubmed.ncbi.nlm.nih.gov/11031256
https://pubmed.ncbi.nlm.nih.gov/11031256