Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Anja Machate"'
Autor:
Laura Celotto, Fabian Rost, Anja Machate, Juliane Bläsche, Andreas Dahl, Anke Weber, Stefan Hans, Michael Brand
Publikováno v:
eLife, Vol 12 (2023)
In the lesioned zebrafish retina, Müller glia produce multipotent retinal progenitors that generate all retinal neurons, replacing lost cell types. To study the molecular mechanisms linking Müller glia reactivity to progenitor production and neuron
Externí odkaz:
https://doaj.org/article/59d77423d0904d32970c4d42dfae17c2
Autor:
Diana Ezhkova, Simone Schwarzer, Sandra Spieß, Michaela Geffarth, Anja Machate, Daniela Zöller, Johanna Stucke, Dimitra Alexopoulou, Mathias Lesche, Andreas Dahl, Stefan Hans
Publikováno v:
Biology Open, Vol 12, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/74e81f6243ee4cb18fb1c811a151d13e
Autor:
Henrike Indrischek, Juliane Hammer, Anja Machate, Nikolai Hecker, Bogdan Kirilenko, Juliana Roscito, Stefan Hans, Caren Norden, Michael Brand, Michael Hiller
Publikováno v:
eLife, Vol 11 (2022)
Despite decades of research, knowledge about the genes that are important for development and function of the mammalian eye and are involved in human eye disorders remains incomplete. During mammalian evolution, mammals that naturally exhibit poor vi
Externí odkaz:
https://doaj.org/article/401fc606f4a84ae2a09373993f44d03c
Autor:
Simone Schwarzer, Devavrat Ravindra Rekhade, Anja Machate, Sandra Spieß, Michaela Geffarth, Diana Ezhkova, Stefan Hans
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Sensorineural hearing loss is caused by the loss of sensory hair cells and/or their innervating neurons within the inner ear and affects millions of people worldwide. In mammals, including humans, the underlying cell types are only produced during fe
Externí odkaz:
https://doaj.org/article/f547550daffe4633a6bc5e7b50fb9a23
Autor:
Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A Semenova, Avinash Chekuru, Paul Wirsching, Volker Kroehne, Saygın Bilican, Shady Sayed, Sylke Winkler, Sandra Spieß, Anja Machate, Jan Kaslin, Pertti Panula, Michael Brand
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009794 (2021)
LRRK2 gain-of-function is considered a major cause of Parkinson's disease (PD) in humans. However, pathogenicity of LRRK2 loss-of-function in animal models is controversial. Here we show that deletion of the entire zebrafish lrrk2 locus elicits a ple
Externí odkaz:
https://doaj.org/article/66a7d68b5aa74d34a2b220b852048894
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
The midbrain-hindbrain boundary (MHB) acts as an organizer and controls the fate of neighboring cells to develop into either mesencephalic (midbrain) or metencephalic (hindbrain) cells by secreting signaling molecules like Wnt1 and Fgf8. The zebrafis
Externí odkaz:
https://doaj.org/article/f3a1ddadeb7e47e09800386ddb619678
Autor:
Julia Ganz, Volker Kroehne, Dorian Freudenreich, Anja Machate, Michaela Geffarth, Ingo Braasch, Jan Kaslin, Michael Brand
Publikováno v:
F1000Research, Vol 3 (2015)
Background: The telencephalon shows a remarkable structural diversity among vertebrates. In particular, the everted telencephalon of ray-finned fishes has a markedly different morphology compared to the evaginated telencephalon of all other vertebrat
Externí odkaz:
https://doaj.org/article/0a417c8dc4cc4e67b68dcbdd6febb07e
Autor:
Julia Ganz, Volker Kroehne, Dorian Freudenreich, Anja Machate, Michaela Geffarth, Ingo Braasch, Jan Kaslin, Michael Brand
Publikováno v:
F1000Research, Vol 3 (2014)
Background: The telencephalon shows a remarkable structural diversity among vertebrates. In particular, the everted telencephalon of ray-finned fishes has a markedly different morphology compared to the evaginated telencephalon of all other vertebrat
Externí odkaz:
https://doaj.org/article/d30ddde6530f4eaa98afdf2d2842efe6
Autor:
Sarah Hochmann, Jan Kaslin, Stefan Hans, Anke Weber, Anja Machate, Michaela Geffarth, Richard H W Funk, Michael Brand
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30365 (2012)
Fibroblast growth factors (Fgf) are secreted signaling molecules that have mitogenic, patterning, neurotrophic and angiogenic properties. Their importance during embryonic development in patterning and morphogenesis of the vertebrate eye is well know
Externí odkaz:
https://doaj.org/article/fd92c3ded8d742dfb16d4a1d56aa097f
Autor:
Alexander Picker, Florencia Cavodeassi, Anja Machate, Sabine Bernauer, Stefan Hans, Gembu Abe, Koichi Kawakami, Stephen W Wilson, Michael Brand
Publikováno v:
PLoS Biology, Vol 7, Iss 10, p e1000214 (2009)
During embryonic development, pattern formation must be tightly synchronized with tissue morphogenesis to coordinate the establishment of the spatial identities of cells with their movements. In the vertebrate retina, patterning along the dorsal-vent
Externí odkaz:
https://doaj.org/article/915e43c916404a0e987a658d3528c2d1