Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anja M Hafkamp"'
Autor:
Pieter J. J. Sauer, WE Bosman, Lisethe Meijer, Ake Bergman, Rick Havinga, Anja M. Hafkamp, Henkjan J. Verkade
Publikováno v:
Journal of Agricultural and Food Chemistry, 54(17), 6440-6444. AMER CHEMICAL SOC
Polybrominated diphenyl ethers are lipophilic persistent organic pollutants (POPs), which accumulate in the environment, leading to human exposure. The compounds exert a negative impact on human health. Strategies to prevent or diminish their accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bf2f4d9131a9218b1739902a6f48fa
https://doi.org/10.1021/jf0608827
https://doi.org/10.1021/jf0608827
Autor:
J. Donald Ostrow, Claudio Tiribelli, Anja M. Hafkamp, Maarten Sinaasappel, Henkjan J. Verkade, Lorella Pascolo, Rick Havinga
Publikováno v:
Pediatric Research, 59(4 Pt 1), 506-512. Lippincott Williams & Wilkins
Pediatric Research, 59(4), 506-512. Nature Publishing Group
Pediatric Research, 59(4), 506-512. Nature Publishing Group
Treatment with phototherapy or with the lipase inhibitor orlistat decreases plasma unconjugated bilirubin (UCB) concentrations in hyperbilirubinemic Gunn rats. We investigated the mechanism(s) underlying the effects of orlistat, phototherapy, and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a53ac8877ba09651fcfc32e88d1f08
https://doi.org/10.1203/01.pdr.0000203180.79636.98
https://doi.org/10.1203/01.pdr.0000203180.79636.98
Publikováno v:
Hepatology, 41(3), 526-534. John Wiley & Sons Ltd.
Hepatology, 41(3), 526-534. Wiley
Hepatology, 41(3), 526-534. Wiley
We sought to develop an oral treatment for unconjugated hyperbilirubinemia. In the Gunn rat model of unconjugated hyperbilirubinemia, dietary supplementation with the lipase inhibitor orlistat (Orl) or with calcium phosphate (CaP) decreases plasma un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54ec62d2815114b5f0b2a8c2946ff28
https://hdl.handle.net/11370/e0ffbabb-2a84-4a58-9883-6441152b3146
https://hdl.handle.net/11370/e0ffbabb-2a84-4a58-9883-6441152b3146
Publikováno v:
Current pharmaceutical design. 15(25)
Severe unconjugated hyperbilirubinemia, seen mainly in neonates, may cause kernicterus and death. Conventional treatment for severe unconjugated hyperbilirubinemia consists of phototherapy and exchange transfusion. Phototherapy, however, has several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2137dbc972cf3a06b48e946865fd15
https://pubmed.ncbi.nlm.nih.gov/19754369
https://pubmed.ncbi.nlm.nih.gov/19754369
Autor:
Rick Havinga, J. Donald Ostrow, Jaroslav Zelenka, Claudio Tiribelli, Libor Vítek, Frans J C Cuperus, Henkjan J. Verkade, Anja M. Hafkamp
Publikováno v:
Gastroenterology, 136(2), 673-682. W B SAUNDERS CO-ELSEVIER INC
Background & Aims: we tested the hypothesis that oral administration of bile salts, which are known to increase the biliary excretion of unconjugated bilirubin (UCB), decreases unconjugated hyperbilirubinemia in the Gunn rat model. Methods: Adult Gun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06599eb5c01a62d8a5b81b10adfa0d5b
https://research.rug.nl/en/publications/76e6878c-036f-4123-aad4-cf14d62e8b24
https://research.rug.nl/en/publications/76e6878c-036f-4123-aad4-cf14d62e8b24
Autor:
Maarten Sinaasappel, Henkjan J. Verkade, Rineke Nelisse-Haak, Ronald P.J. Oude Elferink, Anja M. Hafkamp
Publikováno v:
Pediatric research, 62(6), 725-730. Lippincott Williams and Wilkins
Pediatric Research, 62(6), 725-730. Nature Publishing Group
Pediatric Research, 62(6), 725-730. Nature Publishing Group
Unconjugated hyperbilirubinemia in Crigler-Najjar (CN) disease is conventionally treated with phototherapy and phenobarbital. Orlistat treatment increases fecal fat excretion and decreases plasma unconjugated bifirubin (UCB) concentrations in Gunn ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735a053a8f30a5aa3d0c8c2c9020ec44
https://pure.amc.nl/en/publications/orlistat-treatment-of-unconjugated-hyperbilirubinemia-in-criglernajjar-disease-a-randomized-controlled-trial(e63b9418-1ed9-46de-a49e-fa4f800442e3).html
https://pure.amc.nl/en/publications/orlistat-treatment-of-unconjugated-hyperbilirubinemia-in-criglernajjar-disease-a-randomized-controlled-trial(e63b9418-1ed9-46de-a49e-fa4f800442e3).html
Autor:
Henkjan J. Verkade, Herman Jr Velvis, Pieter P.E. van Lierop, Tomoji Nishioka, Rick Havinga, Anja M. Hafkamp
Publikováno v:
Journal of Pediatrics, 143(3), 327-334. MOSBY-ELSEVIER
University of Groningen
University of Groningen
Objective To determine whether serum levels of unconjugated bilirubin (UCB) can be decreased by enhancing fecal fat excretion. Study design Gunn rats were fed a high-fat diet (control) or the same diet mixed with the lipase inhibitor orlistat. At reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b7a51b2e28b1a5be8b0f59f7bd1125
https://research.rug.nl/en/publications/03592361-20d7-4afc-9a5d-91febf9b097f
https://research.rug.nl/en/publications/03592361-20d7-4afc-9a5d-91febf9b097f
Autor:
Anja M Hafkamp, Henkjan J Verkade
Publikováno v:
Pediatric Research. 65:126-126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccc52a187d59eb3cb024f4d74c4f6637
https://doi.org/10.1203/pdr.0b013e3181943440
https://doi.org/10.1203/pdr.0b013e3181943440
Autor:
Ronald P.J. Oude Elferink, Rick Havinga, Maarten Sinaasappel, Henkjan J. Verkade, Anja M. Hafkamp
Publikováno v:
Gastroenterology. 124:A28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a03b6ab9408503266a289e59daa2f3c4
https://doi.org/10.1016/s0016-5085(03)80136-1
https://doi.org/10.1016/s0016-5085(03)80136-1