Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anja M, Gumpp"'
Autor:
Svenja Müller, Maurizio Sicorello, Dirk Moser, Leonard Frach, Alicia Limberg, Anja M. Gumpp, Laura Ramo-Fernandez, Franziska Köhler-Dauner, Jörg M. Fegert, Christiane Waller, Robert Kumsta, Iris-Tatjana Kolassa
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The oxytocin receptor gene (OXTR) is of interest when investigating the effects of early adversity on DNA methylation. However, there is heterogeneity regarding the selection of the most promising CpG sites to target for analyses. The goal o
Externí odkaz:
https://doaj.org/article/a5a9eac482e545b3936c79fb17201ad9
Autor:
Laura Ramo-Fernández, Anja M. Gumpp, Christina Boeck, Sabrina Krause, Alexandra M. Bach, Christiane Waller, Iris-Tatjana Kolassa, Alexander Karabatsiakis
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The neuropeptide oxytocin (OXT) and its receptor (OXTR) modulate interpersonal relationships, particularly mother–child interactions. DNA methylation (DNAm) changes of the OXTR gene were observed in individuals who experienced Childhood Ma
Externí odkaz:
https://doaj.org/article/eaffa603843a480d945cbd73d64022c4
Autor:
Rezan Nehir Mavioglu, Laura Ramo-Fernandez, Anja M. Gumpp, Iris-Tatjana Kolassa, Alexander Karabatsiakis
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Childhood maltreatment (CM) is associated with alterations in DNA methylation (DNAm) especially in stress response genes. Due to the higher risk of overall health complications of individuals with a parental history of CM, intergenerational transmiss
Externí odkaz:
https://doaj.org/article/5c058efb61644940aa524e39524d3cdb
Autor:
Alexander Behnke, Anja M. Gumpp, Aniko Krumbholz, Alexandra M. Bach, Gustav Schelling, Iris-Tatjana Kolassa, Roberto Rojas
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 7, Iss , Pp 100068- (2021)
Background: Stress-related alterations in the regulation of several endocrine systems, including the hypothalamus-pituitary-adrenal (HPA) and -gonadal (HPG) axes and the endocannabinoid system are proposed to be involved in the etiology of major depr
Externí odkaz:
https://doaj.org/article/b924f0ddd8f04158a48bd65b2aad3ff8
Autor:
Melissa Hitzler, Lynn Matits, Anja M. Gumpp, Alexandra M. Bach, Ute Ziegenhain, Wei Gao, Iris-Tatjana Kolassa, Alexander Behnke
Publikováno v:
Psychological Medicine. :1-12
Background Childhood maltreatment (CM) exerts long-lasting psychological and biological alterations in affected individuals and might also affect the endocannabinoid (eCB) system which modulates inflammation and the endocrine stress response. Here, w
The Association of Childhood Maltreatment With Lipid Peroxidation and DNA Damage in Postpartum Women
Autor:
Christina Boeck, Anja M. Gumpp, Alexandra M. Koenig, Peter Radermacher, Alexander Karabatsiakis, Iris-Tatjana Kolassa
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Childhood maltreatment (CM) is associated with an increased risk for the development of psychiatric and somatic disorders in later life. A potential link could be oxidative stress, which is defined as the imbalance between the amount of reactive oxyg
Externí odkaz:
https://doaj.org/article/97e4c05440df4bda80d7b9e1a29c7ebb
Autor:
Sabrina Krause, Christina Boeck, Anja M. Gumpp, Edit Rottler, Katharina Schury, Alexander Karabatsiakis, Anna Buchheim, Harald Gündel, Iris-Tatjana Kolassa, Christiane Waller
Publikováno v:
Frontiers in Psychology, Vol 9 (2018)
Background: Child maltreatment (CM) and attachment experiences are closely linked to alterations in the human oxytocin (OXT) system. However, human data about oxytocin receptor (OXTR) protein levels are lacking. Therefore, we investigated oxytocin re
Externí odkaz:
https://doaj.org/article/44e7b5e6484348e5a6a4d739304b0501
Autor:
Eva Buck, Martina Zügel, Uwe Schumann, Tamara Merz, Anja M Gumpp, Anke Witting, Jürgen M Steinacker, G Bernhard Landwehrmeyer, Patrick Weydt, Enrico Calzia, Katrin S Lindenberg
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175248 (2017)
Alterations in mitochondrial respiration are an important hallmark of Huntington's disease (HD), one of the most common monogenetic causes of neurodegeneration. The ubiquitous expression of the disease causing mutant huntingtin gene raises the prospe
Externí odkaz:
https://doaj.org/article/02a7a3c494814e5ebf1ddf449e9434ce
Autor:
Anja M. Gumpp, Iris-Tatjana Kolassa, Alexander Behnke, Alexandra M. Bach, Sophia Piller, Christina Boeck, Roberto Rojas
Publikováno v:
Mitochondrion. 58:14-23
Major depressive disorder (MDD) has been associated with lower mitochondrial energy production and higher oxidative stress. We investigated whether these alterations manifest in patients with current mild to moderate MDD severity. We observed no diff
Autor:
Ole Ammerpohl, Anja M. Gumpp, Alexander Karabatsiakis, Laura Ramo-Fernández, Iris-Tatjana Kolassa, R Nehir Mavioglu, Alexandra M. Bach, Christina Boeck
Publikováno v:
Development and Psychopathology. 34:864-874
DNA methylation of the elongation of very long chain fatty acids protein 2 (ELOVL2) was suggested as a biomarker of biological aging, while childhood maltreatment (CM) has been associated with accelerated biological aging. We investigated the associa