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Autor:
Stephen W. Scherer, Luzhang Gao, Aihau Hao, Sharon Chiappa, Wieslaw T. Dura, Theodora Stavrou, Ling Liu, Anja Lowrance, Michael D. Taylor, Corey Raffel, Ron Agatep, Jeremy A. Squire, Chi-chung Hui, Todd G. Mainprize, Brandon J. Wainwright, Alisa M. Goldstein, David Hogg, James T. Rutka, Xiaoyun Zhang
Publikováno v:
Nature Genetics. 31:306-310
The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety of malignancies. Pathway activation is triggered by binding of hedgehog proteins to the multipass Patched-1 (PTCH) recepto