SARS-CoV-2 particles promote airway epithelial differentiation and ciliation

Autor: Julian Gonzalez-Rubio, Vu Thuy Khanh Le-Trilling, Lea Baumann, Maria Cheremkhina, Hannah Kubiza, Anja E. Luengen, Sebastian Reuter, Christian Taube, Stephan Ruetten, Daniela Duarte Campos, Christian G. Cornelissen, Mirko Trilling, Anja Lena Thiebes

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Introduction: The Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, enters the human body via the epithelial cells of the airway tract. To trap and eject pathogens, the a

Externí odkaz: https://doaj.org/article/f28e7f99ee7b4a2abc7feccf177ffcb3

Bone Marrow Derived Mesenchymal Stromal Cells Promote Vascularization and Ciliation in Airway Mucosa Tri-Culture Models in Vitro

Autor: Anja E. Luengen, Maria Cheremkhina, Julian Gonzalez-Rubio, Jan Weckauf, Caroline Kniebs, Hendrik Uebner, E. Miriam Buhl, Christian Taube, Christian G. Cornelissen, Thomas Schmitz-Rode, Stefan Jockenhoevel, Anja Lena Thiebes

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)

Patients suffering from irresectable tracheal stenosis often face limited treatment options associated with low quality of life. To date, an optimal tracheal replacement strategy does not exist. A tissue-engineered tracheal substitute promises to ove

Externí odkaz: https://doaj.org/article/1432b36410bc4e728d4270e4761330bc

Establishment of a Pre-vascularized 3D Lung Cancer Model in Fibrin Gel—Influence of Hypoxia and Cancer-Specific Therapeutics

Autor: Caroline Kniebs, Anja Elisabeth Luengen, Daniel Guenther, Christian Gabriel Cornelissen, Thomas Schmitz-Rode, Stefan Jockenhoevel, Anja Lena Thiebes

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mortality. In order to understand the disease and to develop new treatments, in vitro human lung cancer model systems which imitate the physiological co

Externí odkaz: https://doaj.org/article/001dc9a0c4e4448d93dfa0c034935ec6

FRESH bioprinting technology for tissue engineering – the influence of printing process and bioink composition on cell behavior and vascularization

Autor: Franziska Kreimendahl, Caroline Kniebs, Ana Margarida Tavares Sobreiro, Thomas Schmitz-Rode, Stefan Jockenhoevel, Anja Lena Thiebes

Publikováno v: Journal of Applied Biomaterials & Functional Materials, Vol 19 (2021)

The rapid and tailored biofabrication of natural materials is of high interest for the field of tissue engineering and regenerative medicine. Scaffolds require both high biocompatibility and tissue-dependent mechanical strength to function as basis f

Externí odkaz: https://doaj.org/article/1d69a14fe5464259ae10687a307d1d32

EndOxy

Autor: Sarah Klein, Anja Lena Thiebes, Thomas Schmitz-Rode, Felix Hesselmann, Tanja Berger, Suzana Djeljadini, Stefan Jockenhoevel, Christian Cornelissen

Publikováno v: Annals of biomedical engineering 48(2), 747-756 (2020). doi:10.1007/s10439-019-02401-2
Annals of Biomedical Engineering, 48(2), 747-756. Springer, Cham
Annals of Biomedical Engineering

Annals of biomedical engineering 48(2), 747-756 (2020). doi:10.1007/s10439-019-02401-2
Published by Springer Science + Business Media B.V, Dordrecht [u.a.]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402af94ab9c55bee6bb0a2b02200a9f6
https://doi.org/10.1007/s10439-019-02401-2