Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anja Lechner"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159059 (2016)
To study the impact of psychosocial stress on the immune system, male mice were subjected to chronic subordinate colony housing (CSC), a preclinically validated mouse model for chronic psychosocial stress. CSC substantially affected the cell composit
Externí odkaz:
https://doaj.org/article/5b46e7d46cce4c7bbfdb2a01fb8601b3
Autor:
Thomas Barth, Dominic Schmidt, Catherine Botteron, Trang T T Nguyen, Uwe Ritter, Daniela N Männel, Anja Lechner
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44499 (2012)
Resistance to Leishmania major infection is dependent on the development of a cell-mediated Th1 immune response in resistant C57BL/6 mice whereas Th2-prone BALB/c mice develop non-healing lesions after infection. The chemokine receptor CCR6 is shared
Externí odkaz:
https://doaj.org/article/57050feeead24eb6976f0fe666cf5d1c
Autor:
Johann Pötzl, Catherine Botteron, Eugen Tausch, Xiomara Pedré, André M Mueller, Daniela N Männel, Anja Lechner
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2951 (2008)
BACKGROUND: The function of T helper cell subsets in vivo depends on their location, and one hallmark of T cell differentiation is the sequential regulation of migration-inducing chemokine receptor expression. CC-chemokine receptor 6 (CCR6) is a trai
Externí odkaz:
https://doaj.org/article/90e83cd53870489e8a6c339bc91e4547
Autor:
Anja Lechner
Publikováno v:
Württembergisch Franken. 99:175-182
Autor:
James T. Morton, Philip H. Siebler, Andrea L. Halweg-Edwards, James E. Hassell, Charles L. Raison, James H. Fox, Frederick R. Walker, Rob Knight, Charline Jansch, Dominik Langgartner, Kenneth R. Lowe, Matthew W. Hale, Gerardo Lopez Perez, Jared M. Kopelman, Will Van Treuren, Anja Lechner, Nicole Uschold-Schmidt, Nina C. Donner, Shyamal D. Peddada, Antonio Gonzalez, Benjamin N. Greenwood, Dominic Schmidt, Graham A. W. Rook, Christopher A. Lowry, Monika Fleshner, Kristen J. Wheeler, Andrea M. Füchsl, Stefan O. Reber, David G. Smith
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 22
The prevalence of inflammatory diseases is increasing in modern urban societies. Inflammation increases risk of stress-related pathology; consequently, immunoregulatory or antiinflammatory approaches may protect against negative stress-related outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48630380434c84a5dccd079b4a244526
https://escholarship.org/uc/item/8jx3r6ns
https://escholarship.org/uc/item/8jx3r6ns
Publikováno v:
Clinical Phytoscience. 2
Silymarin has long been used as a hepatoprotective remedy. Chronic toxicity studies in rodents have confirmed that silymarin has a very low toxicity. These data support its history as a safe medication in hepatic diseases. In the last years, several
Autor:
Anja Lechner, Stefan O. Reber, Esther Endlicher, Petra Rümmele, Inga D. Neumann, Nicole Grunwald, Sebastian Peters, Florian Obermeier
Publikováno v:
Stress. 15:403-415
Patients with inflammatory bowel diseases (IBDs) have a higher risk of developing colorectal cancer (CRC) than the general population. Furthermore, chronic psychosocial stress increases the likelihood of developing IBD and multiple types of malignant
Autor:
Sybille Grießl, Johannes Polz, Anja Kammler, Christian Pötschke, Sven Mostböck, Barbara M. Bröker, Anja Lechner, Elisabeth M. Martin, Arno Mohr, Daniela N. Männel
Publikováno v:
European Journal of Immunology. 42:341-352
Immunosuppression, impaired cytokine production and high susceptibility to secondary infections are characteristic for septic patients, and for mice after induction of polymicrobial septic peritonitis by sublethal cecal ligation and puncture (CLP). H
Autor:
Phillip D. Fromm, Leia Wren, Florian Wiede, Heinrich Körner, Erika Cretney, Anja Lechner, Alicia Roomberg, Mark J. Smyth
Publikováno v:
Journal of Leukocyte Biology. 85:108-116
The generalized lymphoproliferative disorder (gld) mouse strain is characterized by severe splenomegaly/lymphadenopathy, the production of autoimmune antibodies, and the appearance of CD4/CD8-negative T cells. An additional TNF deficiency of gld/gld
Publikováno v:
Journal of Leukocyte Biology. 84:162-169
TNF is a pleiotropic cytokine involved in a variety of inflammatory processes and immune responses. TNF effects are mediated via two dis- tinct membrane receptors: TNFR1 and TNFR2. Investigations concerning regulation and function of TNFR2 revealed a