Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anja Lambrechts"'
Autor:
Olivier Debeir, Karima Bakkali, Drieke Vandamme, Christophe Ampe, Matthias Müller, Veronique Jonckheere, Boris Hinz, Marianne Lemaistre, Kris Gevaert, Joël Vandekerckhove, Niklaas Colaert, Evy Timmerman, Davy Waterschoot, An Staes, Christine Decaestecker, Davina Tondeleir, Thierry Doll, Anja Lambrechts
Publikováno v:
Molecular & cellular proteomics, 11 (8
Vertebrate nonmuscle cells express two actin isoforms: cytoplasmic β- and γ-actin. Because of the presence and localized translation of β-actin at the leading edge, this isoform is generally accepted to specifically generate protrusive forces for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449c8a36c3c5382f1f97b2d645f4a5cf
https://doi.org/10.1074/mcp.m111.015099
https://doi.org/10.1074/mcp.m111.015099
Publikováno v:
Cell Motility and the Cytoskeleton. 66:798-815
The dynamic actin cytoskeleton, consisting of six actin isoforms in mammals and a variety of actin binding proteins is essential for all developmental processes and for the viability of the adult organism. Actin isoform specific functions have been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e482cff8fee4b607dc4f35684e36d1e
https://doi.org/10.1002/cm.20350
https://doi.org/10.1002/cm.20350
Publikováno v:
FEBS Letters. 581:211-217
The three dimensional structures of profilins from invertebrates and vertebrates are remarkably similar despite low sequence similarity. Their evolutionary relationship remains thus enigmatic. A phylogenetic analysis of profilins from Deuterostoma in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bebb20b095755a0e7482048250e088
https://doi.org/10.1016/j.febslet.2006.12.013
https://doi.org/10.1016/j.febslet.2006.12.013
Publikováno v:
Journal of Cell Science. 119:4127-4137
Expression of several actin-binding proteins including profilin-1 is up-regulated during capillary morphogenesis of endothelial cells, the biological significance of which remains unknown. Specifically, we hypothesized that profilin-1 is important fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e0fe45fb89a00433c5ed5ba4b87ec5
https://doi.org/10.1242/jcs.03178
https://doi.org/10.1242/jcs.03178
Autor:
Christophe Ampe, Winnok H. De Vos, Anja Lambrechts, Veronique Jonckheere, Joël Vandekerckhove, Christa Peleman, Debby Polet
Publikováno v:
Journal of Cell Science. 119:1570-1578
Differentiating neurons extend membrane protrusions that develop into growing neurites. The driving force for neurite outgrowth is the dynamic actin cytoskeleton, which is regulated by actin-binding proteins. In this study, we describe for the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106df95083f53ec8fd03881db0b51bcb
https://doi.org/10.1242/jcs.02884
https://doi.org/10.1242/jcs.02884
Autor:
Anja Lambrechts, Christophe Ampe, Kanako Ono, Joël Vandekerckhove, A Mah, Dl Baillie, Shoichiro Ono, Frank Peelman, Debby Polet
Publikováno v:
Cell Motility and the Cytoskeleton. 63:14-28
Profilins are actin binding proteins, which also interact with polyphosphoinositides and proline-rich ligands. On the basis of the genome sequence, three diverse profilin homologues (PFN) are predicted to exist in Caenorhabditis elegans. We show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29de58d3761b9fee61207d4d63504eb3
https://doi.org/10.1002/cm.20102
https://doi.org/10.1002/cm.20102
Autor:
Joël Vandekerckhove, Reinhard Fässler, Inge Van Colen, Attila Braun, Anja Lambrechts, Attila Aszódi, Christophe Ampe, Lorene M. Lanier, Johan Robbens, Veronique Jonckheere
Publikováno v:
Molecular and Cellular Biology. 20:8209-8219
We deduced the structure of the mouse profilin II gene. It contains five exons that can generate four different transcripts by alternative splicing. Two transcripts encode different profilin II isoforms (designated IIa and IIb) that have similar affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720bd9a72de68e5a07ffe7ca6a670965
https://doi.org/10.1128/mcb.20.21.8209-8219.2000
https://doi.org/10.1128/mcb.20.21.8209-8219.2000
Autor:
Frank B. Gertler, Christophe Ampe, Anja Lambrechts, Adam V. Kwiatkowski, Lorene M. Lanier, Joël Vandekerckhove, James E. Bear
Publikováno v:
Journal of Biological Chemistry. 275:36143-36151
Proteins of the Ena/VASP family are implicated in processes that require dynamic actin remodeling such as axon guidance and platelet activation. In this work, we explored some of the pathways that likely regulate actin dynamics in part via EVL (Ena/V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b025d2857d9985d7c1d7391df406d6d1
https://doi.org/10.1074/jbc.m006274200
https://doi.org/10.1074/jbc.m006274200
The mammalian profilin isoforms display complementary affinities for PIP2 and proline-rich sequences
Autor:
Anja Lambrechts, Christophe Ampe, Joël Vandekerckhove, M Goethals, Veronique Jonckheere, Jean-Luc Verschelde
Publikováno v:
The EMBO Journal. 16:484-494
We present a study on the binding properties of the bovine profilin isoforms to both phosphatidylinositol 4,5-bisphosphate (PIP2) and proline-rich peptides derived from vasodilator-stimulated phosphoprotein (VASP) and cyclase-associated protein (CAP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72e30e92d4dbd560f480face5cbb250
https://doi.org/10.1093/emboj/16.3.484
https://doi.org/10.1093/emboj/16.3.484
Publikováno v:
European Journal of Biochemistry. 230:281-286
We purified profilin from bovine brain and were able to separate the two isoforms present in this tissue. Since functional characteristics for profilin II are lacking, we assayed the actin, the phosphatidylinositol 4,5-bisphosphate and the poly(L-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506e14e3fc2f380fa7a559d430b94213
https://doi.org/10.1111/j.1432-1033.1995.0281i.x
https://doi.org/10.1111/j.1432-1033.1995.0281i.x