Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anja Krones-Herzig"'
Autor:
Bilgen Ekim Üstünel, Kilian Friedrich, Adriano Maida, Xiaoyue Wang, Anja Krones-Herzig, Oksana Seibert, Anke Sommerfeld, Allan Jones, Tjeerd P. Sijmonsma, Carsten Sticht, Norbert Gretz, Thomas Fleming, Peter P. Nawroth, Wolfgang Stremmel, Adam J. Rose, Mauricio Berriel-Diaz, Matthias Blüher, Stephan Herzig
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
TSC22D4 regulates hepatic lipoprotein production, but has so far mainly been studied in the context of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse models of diabetes, which they attribute a
Externí odkaz:
https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 3, Pp 218-228 (2003)
Despite remarkable advances in our understanding of a genetic basis of cancer, the precise molecular definition of the phenotypically relevant genetic features associated with human epithelial malignancies remains a significant and highly relevant ch
Externí odkaz:
https://doaj.org/article/84aefdf0ec9f4858842d0552de625db0
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42166 (2012)
FOXO3 is a transcription factor involved in the regulation of multiple physiological processes including cell cycle arrest, apoptosis, oxidative stress-response and energy metabolism. Although much is known about its post-translational modification,
Externí odkaz:
https://doaj.org/article/dd8f1d7e6397484a8e5d7609148a7b58
Autor:
Dan Mercola, Eileen D. Adamson, Tarun Soni, Rafael Urcis, Chris English, Hongyan Liang, Kelly Yule, Shalu Mittal, Anja Krones-Herzig
The early growth response 1 (Egr1) gene is a transcription factor that acts as both a tumor suppressor and a tumor promoter. Egr1-null mouse embryo fibroblasts bypass replicative senescence and exhibit a loss of DNA damage response and an apparent im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cd8e53e20eeb373aff7b95093f0e03
https://doi.org/10.1158/0008-5472.c.6493605.v1
https://doi.org/10.1158/0008-5472.c.6493605.v1
Autor:
Dan Mercola, Eileen D. Adamson, Tarun Soni, Rafael Urcis, Chris English, Hongyan Liang, Kelly Yule, Shalu Mittal, Anja Krones-Herzig
Supplementary Materials and Table 1 from Early Growth Response 1 Acts as a Tumor Suppressor In vivo and In vitro via Regulation of p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5e4c540685da3c9a2160c389934f99
https://doi.org/10.1158/0008-5472.22363215
https://doi.org/10.1158/0008-5472.22363215
Autor:
Tjeerd P. Sijmonsma, Wolfgang Stremmel, Peter P. Nawroth, Adam J. Rose, Mauricio Berriel-Diaz, Carsten Sticht, Matthias Blüher, Kilian Friedrich, Stephan Herzig, Allan Jones, Norbert Gretz, Xiaoyue Wang, Adriano Maida, Anke Sommerfeld, Bilgen Ekim Üstünel, Thomas Fleming, Anja Krones-Herzig, Oksana Seibert
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nat. Commun. 7:13267 (2016)
Nature Communications
Nat. Commun. 7:13267 (2016)
Obesity-related insulin resistance represents the core component of the metabolic syndrome, promoting glucose intolerance, pancreatic beta cell failure and type 2 diabetes. Efficient and safe insulin sensitization and glucose control remain critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed865424855d4c6f3c04658015922e33
https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2
https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2
Autor:
Jan Tuckermann, Mauricio Berriel Diaz, Achim Peters, Anja Reimann, Oliver Strobel, Anna Kleyman, Jens Werner, Stephan Herzig, Adam J. Rose, Tessa Walcher, Alexandros Vegiopoulos, Johanna Klement, Anja Krones-Herzig
Publikováno v:
Cell Metabolism. 14:123-130
Summary Systemic bile acid (BA) homeostasis is a critical determinant of dietary fat digestion, enterohepatic function, and postprandial thermogenesis. However, major checkpoints for the dynamics and the molecular regulation of BA homeostasis remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabb090d98d794aa51ca4cd97bdd1948
https://doi.org/10.1016/j.cmet.2011.04.010
https://doi.org/10.1016/j.cmet.2011.04.010
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2010, 332 (1-2), pp.21. ⟨10.1016/j.mce.2010.11.020⟩
Molecular and Cellular Endocrinology, Elsevier, 2010, 332 (1-2), pp.21. ⟨10.1016/j.mce.2010.11.020⟩
International audience; After binding to their cognate DNA-binding partner, transcriptional co-factors exert their function through the recruitment of enzymatic, chromatin-modifying activities. In turn, the assembly of co-factor-associated multi-prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65de99a62da46feca33561a0d5e6ad4f
https://doi.org/10.1016/j.mce.2010.11.020
https://doi.org/10.1016/j.mce.2010.11.020
Autor:
Mauricio Berriel Diaz, Ulrike Hardeland, Prachiti Narvekar, Daniela Strzoda, Sigrid Stöhr, Marcus Frohme, Anja Krones-Herzig, Stephan Herzig
Publikováno v:
Diabetes
OBJECTIVE In mammals, proper storage and distribution of lipids in and between tissues is essential for the maintenance of energy homeostasis. In contrast, aberrantly high levels of triglycerides in the blood (“hypertriglyceridemia”) represent a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e05466e977b4af9d9a853851249e48
https://doi.org/10.2337/db08-1184
https://doi.org/10.2337/db08-1184
Autor:
Karin Müller-Decker, Mauricio Berriel Diaz, Ulrike Lemke, Anja Ziegler, Anja Krones-Herzig, Prachiti Narvekar, Andrew C.B. Cato, Ursula Klingmüller, Robert A. Screaton, Stephan Herzig, Alexandros Vegiopoulos, Sebastian Bohl, Sander Kersten
Publikováno v:
Cell Metabolism 8 (2008) 3
Cell Metabolism, 8(3), 212-223
Cell Metabolism, 8(3), 212-223
SummaryAberrant accumulation of lipids in the liver (“fatty liver” or hepatic steatosis) represents a hallmark of the metabolic syndrome and is tightly associated with obesity, type II diabetes, starvation, or glucocorticoid (GC) therapy. While f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75245a9e88e756b72ba1f0e3d433f45
https://doi.org/10.1016/j.cmet.2008.08.001
https://doi.org/10.1016/j.cmet.2008.08.001