Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anja K. Holzer"'
Autor:
Johann H. Sattler, Mathias Pickl, Wilfried Banko, Wolfgang Kroutil, Dominik Koszelewski, Katharina Tauber, Kurt Faber, Michael Fuchs, Anja K. Holzer
Publikováno v:
Tetrahedron. 68:7691-7694
(S)-Rivastigmine [(S)-1] was obtained via a four-step synthesis using an asymmetric enzymatic transamination protocol as the key step. An early introduction of the carbamate pharmacophore side chain avoided the use of protective group strategies and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b879914ee87df2c9a980f46e380adb7
https://doi.org/10.1016/j.tet.2012.06.031
https://doi.org/10.1016/j.tet.2012.06.031
Autor:
Oliver Lenz, Lars Lauterbach, Katharina Hiebler, Francesco G. Mutti, Wolfgang Kroutil, Anja K. Holzer, Robert C. Simon
Publikováno v:
Organic letters. 17(10)
A biocatalytic system is presented for the stereoselective amination of ketones at the expense of NH3 and molecular hydrogen. By using a NAD(+)-reducing hydrogenase, an alanine dehydrogenase, and a suitable ω-transaminase, the R- as well as the S-en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908bcf1cd1626e0ff4b4ab1ed688fdee
https://pubmed.ncbi.nlm.nih.gov/25946312
https://pubmed.ncbi.nlm.nih.gov/25946312