Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Anja Irmisch"'
Autor:
Anna Spreafico, Eva Muñoz Couselo, Anja Irmisch, Juliana Bessa, George Au-Yeung, Oliver Bechter, Inge Marie Svane, Miguel F. Sanmamed, Valentina Gambardella, Meredith McKean, Margaret Callahan, Reinhard Dummer, Christian Klein, Pablo Umaña, Nicole Justies, Florian Heil, Linda Fahrni, Eugenia Opolka-Hoffmann, Inja Waldhauer, Conrad Bleul, Roland F. Staack, Vaios Karanikas, Stephen Fowler
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAlthough checkpoint inhibitors (CPIs) have improved outcomes for patients with metastatic melanoma, those progressing on CPIs have limited therapeutic options. To address this unmet need and overcome CPI resistance mechanisms, novel immun
Externí odkaz:
https://doaj.org/article/1b6cf328c2214d24859fac4cbcd710e0
Autor:
Thomas J Etheridge, Desiree Villahermosa, Eduard Campillo-Funollet, Alex David Herbert, Anja Irmisch, Adam T Watson, Hung Q Dang, Mark A Osborne, Antony W Oliver, Antony M Carr, Johanne M Murray
Publikováno v:
eLife, Vol 10 (2021)
The essential Smc5/6 complex is required in response to replication stress and is best known for ensuring the fidelity of homologous recombination. Using single-molecule tracking in live fission yeast to investigate Smc5/6 chromatin association, we s
Externí odkaz:
https://doaj.org/article/a87f3e7fa1b34575930f08ff8d91c899
Autor:
Franziska Singer, Anja Irmisch, Nora C. Toussaint, Linda Grob, Jochen Singer, Thomas Thurnherr, Niko Beerenwinkel, Mitchell P. Levesque, Reinhard Dummer, Luca Quagliata, Sacha I. Rothschild, Andreas Wicki, Christian Beisel, Daniel J. Stekhoven
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 18, Iss 1, Pp 1-18 (2018)
Abstract Background Molecular precision oncology is an emerging practice to improve cancer therapy by decreasing the risk of choosing treatments that lack efficacy or cause adverse events. However, the challenges of integrating molecular profiling in
Externí odkaz:
https://doaj.org/article/fc0a60e3820f4bb481a3a59f28c85971
Autor:
Mitchell P. Levesque, Reinhard Dummer, Berend Snijder, Martin Distel, Thorsten Hornemann, Stuart L. Schreiber, Michael Krauthammer, Andreas Dzung, Annalisa Saltari, Andrea Aloia, Judith Wenzina, Vasanthi S. Viswanathan, Alaa Othman, Julien Mena, Rebekka Wegmann, Pål Johansen, Susana Pascoal, Aizhan Tastanova, Zsolt Balazs, Anja Irmisch, Nicola Zamboni, Andrea Bileck, Alexander Leitner, Phil F. Cheng, Verena Paulitschke, Nina Zila, Gergely Karsai, Patrick Turko, Luzia Briker, Jan Käsler, Corinne I. Stoffel, Ossia M. Eichhoff
Tumor Profiler Consortium author list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793b5a380d7fd2ae0dc078b2363f59f
https://doi.org/10.1158/0008-5472.22549700.v1
https://doi.org/10.1158/0008-5472.22549700.v1
Autor:
Mitchell P. Levesque, Reinhard Dummer, Berend Snijder, Martin Distel, Thorsten Hornemann, Stuart L. Schreiber, Michael Krauthammer, Andreas Dzung, Annalisa Saltari, Andrea Aloia, Judith Wenzina, Vasanthi S. Viswanathan, Alaa Othman, Julien Mena, Rebekka Wegmann, Pål Johansen, Susana Pascoal, Aizhan Tastanova, Zsolt Balazs, Anja Irmisch, Nicola Zamboni, Andrea Bileck, Alexander Leitner, Phil F. Cheng, Verena Paulitschke, Nina Zila, Gergely Karsai, Patrick Turko, Luzia Briker, Jan Käsler, Corinne I. Stoffel, Ossia M. Eichhoff
Table ST5: Table of the 15 most informative proteins upregulated in MEK inhibitor-resistant cell culture (ranked by log2 fold-change).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab8c00b4082577dcc6041ba84a6950b
https://doi.org/10.1158/0008-5472.22549685
https://doi.org/10.1158/0008-5472.22549685
Autor:
Mitchell P. Levesque, Reinhard Dummer, Berend Snijder, Martin Distel, Thorsten Hornemann, Stuart L. Schreiber, Michael Krauthammer, Andreas Dzung, Annalisa Saltari, Andrea Aloia, Judith Wenzina, Vasanthi S. Viswanathan, Alaa Othman, Julien Mena, Rebekka Wegmann, Pål Johansen, Susana Pascoal, Aizhan Tastanova, Zsolt Balazs, Anja Irmisch, Nicola Zamboni, Andrea Bileck, Alexander Leitner, Phil F. Cheng, Verena Paulitschke, Nina Zila, Gergely Karsai, Patrick Turko, Luzia Briker, Jan Käsler, Corinne I. Stoffel, Ossia M. Eichhoff
S13: Immunohistochemical analysis of CyTof biomarker panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4117e07f527972268e9d33eaec557930
https://doi.org/10.1158/0008-5472.22549733.v1
https://doi.org/10.1158/0008-5472.22549733.v1
Autor:
Mitchell P. Levesque, Reinhard Dummer, Berend Snijder, Martin Distel, Thorsten Hornemann, Stuart L. Schreiber, Michael Krauthammer, Andreas Dzung, Annalisa Saltari, Andrea Aloia, Judith Wenzina, Vasanthi S. Viswanathan, Alaa Othman, Julien Mena, Rebekka Wegmann, Pål Johansen, Susana Pascoal, Aizhan Tastanova, Zsolt Balazs, Anja Irmisch, Nicola Zamboni, Andrea Bileck, Alexander Leitner, Phil F. Cheng, Verena Paulitschke, Nina Zila, Gergely Karsai, Patrick Turko, Luzia Briker, Jan Käsler, Corinne I. Stoffel, Ossia M. Eichhoff
S16: scRNA-sequencing analysis of xenograft tumors M130227
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128793efeb32aca7a82defd37edef78f
https://doi.org/10.1158/0008-5472.22549703
https://doi.org/10.1158/0008-5472.22549703
Autor:
Werner J. Kovacs, Wilhelm Krek, Mitchell P. Levesque, Gao Zhang, Reinhard Dummer, Nicola Zamboni, Keith T. Flaherty, Meenhard Herlyn, Genevieve M. Boland, Ryan J. Sullivan, Zhi Wei, Lawrence N. Kwong, Chaoran Cheng, Tian Tian, Benchun Miao, Dennie T. Frederick, Ernesto Scibona, Leila T. Alexander, Anja Irmisch, Ossia Eichhoff, Ana Vukolic, Stefanie Flückiger-Mangual, Tanja Eberhart, Christophe D. Chabbert, Daniela Müllhaupt, Andrea Aloia
Table S5, related to Figure S5C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbde37b82bb268788568148efc2e1cdf
https://doi.org/10.1158/1078-0432.22471953.v1
https://doi.org/10.1158/1078-0432.22471953.v1
Autor:
Werner J. Kovacs, Wilhelm Krek, Mitchell P. Levesque, Gao Zhang, Reinhard Dummer, Nicola Zamboni, Keith T. Flaherty, Meenhard Herlyn, Genevieve M. Boland, Ryan J. Sullivan, Zhi Wei, Lawrence N. Kwong, Chaoran Cheng, Tian Tian, Benchun Miao, Dennie T. Frederick, Ernesto Scibona, Leila T. Alexander, Anja Irmisch, Ossia Eichhoff, Ana Vukolic, Stefanie Flückiger-Mangual, Tanja Eberhart, Christophe D. Chabbert, Daniela Müllhaupt, Andrea Aloia
Contains Supplementary materials and methods, Supplementary Figures S1-S9, Table S2, Table S4, Supplemental References Figure S1, related to Figure 1. Cell surface marker screening of A375P cells treated with vehicle (DMSO) or PLX. Figure S2, related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861c966b97796fdaf5734665c05f4982
https://doi.org/10.1158/1078-0432.22471962.v1
https://doi.org/10.1158/1078-0432.22471962.v1
Autor:
Mitchell P. Levesque, Reinhard Dummer, Berend Snijder, Martin Distel, Thorsten Hornemann, Stuart L. Schreiber, Michael Krauthammer, Andreas Dzung, Annalisa Saltari, Andrea Aloia, Judith Wenzina, Vasanthi S. Viswanathan, Alaa Othman, Julien Mena, Rebekka Wegmann, Pål Johansen, Susana Pascoal, Aizhan Tastanova, Zsolt Balazs, Anja Irmisch, Nicola Zamboni, Andrea Bileck, Alexander Leitner, Phil F. Cheng, Verena Paulitschke, Nina Zila, Gergely Karsai, Patrick Turko, Luzia Briker, Jan Käsler, Corinne I. Stoffel, Ossia M. Eichhoff
Clinical management of melanomas with NRAS mutations is challenging. Targeting MAPK signaling is only beneficial to a small subset of patients due to resistance that arises through genetic, transcriptional, and metabolic adaptation. Identification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273c0a1e2eba8759723b206ea2872e31
https://doi.org/10.1158/0008-5472.c.6514435.v1
https://doi.org/10.1158/0008-5472.c.6514435.v1