Výsledky vyhledávání - "Anja Hillmann"

Akademický článek

Cell surface-bound TIMP3 induces apoptosis in mesenchymal Cal78 cells through ligand-independent activation of death receptor signaling and blockade of survival pathways.

Autor: Christina Koers-Wunrau, Corinna Wehmeyer, Anja Hillmann, Thomas Pap, Berno Dankbar

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e70709 (2013)

BACKGROUND: The matrix metalloproteinases (MMPs) and their endogenous regulators, the tissue inhibitor of metalloproteinases (TIMPs 1-4) are responsible for the physiological remodeling of the extracellular matrix (ECM). Among all TIMPs, TIMP3 appear

Externí odkaz: https://doaj.org/article/05a7a4a30ed7479fa80012bee8c57448

Zobrazit plný text záznamu

Regulation of matrixmetalloproteinase-3 and matrixmetalloproteinase-13 by SUMO-2/3 through the transcription factor NF-κB

Autor: Svetlana Frank, Marvin A Peters, Corinna Wehmeyer, Simon Strietholt, Christina Koers-Wunrau, Jessica Bertrand, Marianne Heitzmann, Anja Hillmann, Joanna Sherwood, Christine Seyfert, Steffen Gay, Thomas Pap

Publikováno v: Annals of the Rheumatic Diseases. 72:1874-1881

Objective Based on previous data that have linked the small ubiquitin-like modifier-1 (SUMO-1) to the pathogenesis of rheumatoid arthritis (RA), we have investigated the expression of the highly homologous SUMO family members SUMO-2/3 in human RA and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b0ae401269c9c18e848136ec184e87
https://doi.org/10.1136/annrheumdis-2012-202080

Zobrazit plný text záznamu

ADAM10 is expressed in human podocytes and found in urinary vesicles of patients with glomerular kidney diseases

Autor: Wolfgang Eberhardt, Peter Altevogt, Anja Hillmann, Andreas Ludwig, Christine Jespersen, Anja Schramme, Mohamed S. Abdel-Bakky, Josef Pfeilschifter, Ingeborg A. Hauser, Paul Gutwein, Stefan Gauer, Kai Doberstein, Thomas Weide

Publikováno v: Journal of Biomedical Science
Journal of biomedical science 17, 3 (2010). doi:10.1186/1423-0127-17-3
Journal of Biomedical Science, Vol 17, Iss 1, p 3 (2010)

Journal of biomedical science 17, 3 (2010). doi:10.1186/1423-0127-17-3
Published by BioMed Central, London

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9f500c8fb18aa46ef3ca6b288e1cfb
https://pubmed.ncbi.nlm.nih.gov/20070888

Zobrazit plný text záznamu

A2.13 DNA-antibody complexes are internalised by podocytes

Autor: M Reinhardt, E. Jung, Annika Engbers, Thomas Pap, A.M. Jacobi, Anja Hillmann, Hedda Wardemann, M Rieger

Publikováno v: Annals of the Rheumatic Diseases. 74:A20.3-A21

Background and objectives Systemic lupus erythematosus (SLE) causes inflammation and damage of various organs, often of the kidney (Lupus nephritis, LN). The occurrence of antibodies against double stranded DNA (adsDNAabs) is a hallmark of the diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cc250625ca26d68ca32b00bd5e4a54d
https://doi.org/10.1136/annrheumdis-2015-207259.48

Zobrazit plný text záznamu

THU0018 Sumo specific proteases 5 and 7 contribute to the inbalanced sumoylation level of rheumatoid athritis synovial fibroblasts

Autor: Svetlana Frank, Thomas Pap, Simon Strietholt, Anja Hillmann, Marvin A. Peters, George Kollias

Publikováno v: Annals of the Rheumatic Diseases. 71:159.3-159

Background It has been shown previousely that posttranslational protein modification through SUMOylation is enhanced in rheumatoid athritis synovial fibroblasts (RASF) compared to osteoathritis synovial fibroblasts (OASF) and that higher levels of SU

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::241ef55c29e685a00c388a0c3b27d1d3
https://doi.org/10.1136/annrheumdis-2012-eular.1983

Zobrazit plný text záznamu

SAT0159 Podocyte damage by autoantibodies in lupus nephritis

Autor: Thomas Pap, E. Jung, Hedda Wardemann, A.M. Jacobi, Anja Hillmann

Publikováno v: Annals of the Rheumatic Diseases. 71:525.3-526

Background Systemic lupus erythematosus (SLE) is an autoimmune disease, resulting in inflammation and tissue damage in several organs. This autoimmune reaction is caused by antibodies against dsDNA (adsDNAabs). Most patients with SLE develop joint pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45abfa75ff351a86deb2d790149b235e
https://doi.org/10.1136/annrheumdis-2012-eular.3106

Zobrazit plný text záznamu

Uptake of SLE autoantibodies by podocytes

Autor: Thomas Pap, Anja Hillmann, Hedda Wardemann, A.M. Jacobi

Publikováno v: Annals of the Rheumatic Diseases. 71:A32.3-A33

Backgroundand objectives Systemic lupus erythematosus (SLE) is an autoimmune disease, resulting in inflammation and tissue damage in several organs. This autoimmune reaction is caused by antibodies against dsDNA (adsDNAabs). Most patients with SLE de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf28a78e175fba21b8b13c37acf6b896
https://doi.org/10.1136/annrheumdis-2011-201234.2

Zobrazit plný text záznamu

The TRAF6 binding molecule p62/SQSTM1 is a critical regulator of inflammatory bone destruction

Autor: Michael Schäfers, André Gessner, Sven Hermann, H Pavenstädt, Thomas Pap, Thomas Weide, Adelheid Korb, Anja Hillmann, George Kollias, Susanne Bürgis

Publikováno v: Annals of the Rheumatic Diseases. 69:A19-A19

The activation of nuclear factor κB (NFκB) via RANK is essential in regulating osteoclastogenesis. Under inflammatory conditions this process is enhanced by cytokines such as tumour necrosis factor α (TNFα). P62/SQSTM1 directly modulates these pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e26b262fb0271789c5a137be2b32d078
https://doi.org/10.1136/ard.2010.129593j

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání