Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anja Heymans"'
Autor:
Joost Boeckmans, Alexandra Gatzios, Anja Heymans, Matthias Rombaut, Vera Rogiers, Joery De Kock, Tamara Vanhaecke, Robim M. Rodrigues
Publikováno v:
Cells, Vol 11, Iss 5, p 893 (2022)
Background and aims: Non-alcoholic steatohepatitis (NASH) is a life-threatening stage of non-alcoholic fatty liver disease (NAFLD) for which no drugs have been approved. We have previously shown that human-derived hepatic in vitro models can be used
Externí odkaz:
https://doaj.org/article/92afa28c530f405bbeeadc4e6899147e
Autor:
Jessie Neuckermans, Sien Lequeue, Paul Claes, Anja Heymans, Juliette H. Hughes, Haaike Colemonts-Vroninks, Lionel Marcélis, Georges Casimir, Philippe Goyens, Geert A. Martens, James A. Gallagher, Tamara Vanhaecke, George Bou-Gharios, Joery De Kock
Publikováno v:
Genes; Volume 14; Issue 3; Pages: 693
Hereditary tyrosinemia type 1 (HT1) is a genetic disorder of the tyrosine degradation pathway (TIMD) with unmet therapeutic needs. HT1 patients are unable to fully break down the amino acid tyrosine due to a deficient fumarylacetoacetate hydrolase (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf205983b81b8fede96d9f6db53217dd
Autor:
Vera Rogiers, Anja Heymans, Joost Boeckmans, Veerle De Boe, Matthias Rombaut, Joery De Kock, Tamara Vanhaecke, Alessandra Natale, Brent Cami, Robim Marcelino Rodrigues, Karolien Buyl
Publikováno v:
Cell Biology and Toxicology. 37:293-311
Non-alcoholic steatohepatitis (NASH) is a highly prevalent, chronic liver disease characterized by hepatic lipid accumulation, inflammation, and concomitant fibrosis. Up to date, no anti-NASH drugs have been approved. In this study, we reproduced key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df274c7e0e1fe89ca71333141a57281a
https://doi.org/10.1007/s10565-020-09544-2
https://doi.org/10.1007/s10565-020-09544-2
Autor:
Dimiter Milushev, Vera Rogiers, Alessandra Roncaglioni, Giuseppa Raitano, Anja Heymans, Gamze Ates, Emilio Benfenati, Philippe Vanparys, Melissa Van Bossuyt, Birgit Mertens, Christophe Chesne, Tatyana Y. Doktorova
Publikováno v:
Mutagenesis
Prior to the downstream development of chemical substances, including pharmaceuticals and cosmetics, their influence on the genetic apparatus has to be tested. Several in vitro and in vivo assays have been developed to test for genotoxicity. In a fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa287b099e18d3226acadaad791e37e8
https://doi.org/10.1093/mutage/gew008
https://doi.org/10.1093/mutage/gew008
Autor:
Gamze Ates, Vera Rogiers, Birgit Mertens, Luc Verschaeve, Nancy H. C. Roosens, Sigrid C. J. De Keersmaecker, Anja Heymans, Philippe Vanparys, Dimiter Milushev, Tatyana Y. Doktorova
Publikováno v:
Archives of toxicology
Although the value of the regulatory accepted batteries for in vitro genotoxicity testing is recognized, they result in a high number of false positives. This has a major impact on society and industries developing novel compounds for pharmaceutical,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3087c9d134b1148e6623bef533d65ecf
https://hdl.handle.net/20.500.14017/c331c824-7974-4ef8-acad-b3219d0a0932
https://hdl.handle.net/20.500.14017/c331c824-7974-4ef8-acad-b3219d0a0932
Autor:
Joery De Kock, Tamara Vanhaecke, Veerle De Boe, Tania Roskams, Vera Rogiers, Robim Marcelino Rodrigues, Olivier Govaere, Umesh Chaudhari, Anja Heymans, Agapios Sachinidis
Publikováno v:
Toxicology letters. 240(1)
Primary human hepatocytes (hHEP), human HepaRG and HepG2 cell lines are the most used human liver-based in vitro models for hepatotoxicity testing, including screening of drug-induced liver injury (DILI)-inducing compounds. hHEP are the reference hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412d82e2db6c0adbce59c51c89fda4fa
https://pubmed.ncbi.nlm.nih.gov/26497421
https://pubmed.ncbi.nlm.nih.gov/26497421
Autor:
Yordanova Doktorova Tatyana, Reha Yildirimman, Liesbeth Ceelen, Mireia Vilardell, Tamara Vanhaecke, Mathieu Vinken, Gamze Ates, Anja Heymans, Hans Gmuender, Roque Bort, Raffaella Corvi, Pascal Phrakonkham, Ruoya Li, Nicolas Mouchet, Christophe Chesne, Joost Van Delft, Jos Kleinjans, José Castell, Ralf Herwig, Vera Rogiers
Publikováno v:
EXCLI Journal
Experimental and Clinical Sciences Journal (EXCLI Journal)
Europe PubMed Central
Excli Journal, 13, 623-637. EXCLI Journal
Vrije Universiteit Brussel
Scopus-Elsevier
EXCLI JOURNAL
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Experimental and Clinical Sciences Journal (EXCLI Journal)
Europe PubMed Central
Excli Journal, 13, 623-637. EXCLI Journal
Vrije Universiteit Brussel
Scopus-Elsevier
EXCLI JOURNAL
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
The EU FP6 project carcinoGENOMICS explored the combination of toxicogenomics and in vitro cell culture models for identifying organotypical genotoxic- and non-genotoxic carcinogen- specific gene signatures. Here the performance of its gene classifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109cdf8dded4c8db34398ef3837fc3db
http://hdl.handle.net/2003/33541
http://hdl.handle.net/2003/33541
Autor:
Anja Heymans, Simke Demeester, Vera Rogiers, Joery De Kock, Steven Branson, Tamara Vanhaecke, Sarah Snykers, Eva Ramboer
In the present study, the trilineage differentiation capacity of human foreskin-derived precursor cells (hSKP) was evaluated upon exposure to various (non)commercial (i and ii) ectodermal, (iii) mesodermal and (iv) endodermal differentiation media. (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b170a543bfd14b982b7f51216ce38e
https://hdl.handle.net/20.500.14017/364bdad1-41c7-46e6-ba76-f495460eb340
https://hdl.handle.net/20.500.14017/364bdad1-41c7-46e6-ba76-f495460eb340
Autor:
Joery De Kock, Sarah Snykers, Eva Ramboer, Demeester Simke, Anja Heymans, Steven Branson, Tamara Vanhaecke, Vera Rogiers
Publikováno v:
Vrije Universiteit Brussel
In the present study, the trilineage differentiation capacity of human foreskin-derived precursor cells (hSKP) was evaluated upon exposure to various (non)commercial (i and ii) ectodermal, (iii) mesodermal and (iv) endodermal differentiation media. (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::52000fb2a5044162aa85810adbe4a870
https://hdl.handle.net/20.500.14017/582a4c19-e5f1-4aba-9868-d8b4630af514
https://hdl.handle.net/20.500.14017/582a4c19-e5f1-4aba-9868-d8b4630af514
Autor:
Feras Albattah, Joery De Kock, Eva Ramboer, Anja Heymans, Tamara Vanhaecke, Vera Rogiers, Sarah Snykers
Publikováno v:
Vrije Universiteit Brussel
In the present study, the multipotent potential of two differently isolated human adipose derived stem cell (hADSC) populations was evaluated. More specifically, hADSC isolated by means of classical ficoll (F) gradient centrifugation were compared to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::636a8b41e92853273d5d2290370b7410
https://biblio.vub.ac.be/vubir/evaluation-of-the-multipotent-character-of-human-adipose-derived-stem-cells-isolated-by-ficoll-gradient-centrifugation-and-red-blood-cell-lysis-treatment(af7872b1-63f2-4511-a1ce-7fd8ec2d9177).html
https://biblio.vub.ac.be/vubir/evaluation-of-the-multipotent-character-of-human-adipose-derived-stem-cells-isolated-by-ficoll-gradient-centrifugation-and-red-blood-cell-lysis-treatment(af7872b1-63f2-4511-a1ce-7fd8ec2d9177).html