Divergent effects of a designer natriuretic peptide CD-NP in the regulation of adipose tissue and metabolism

Autor: Anja Glöde, Jennifer Naumann, Thorsten Gnad, Valentina Cannone, Ana Kilic, John C. Burnett, Jr., Alexander Pfeifer

Publikováno v: Molecular Metabolism, Vol 6, Iss 3, Pp 276-287 (2017)

Objective: Obesity is defined as an abnormal increase in white adipose tissue (WAT) and is a major risk factor for type 2 diabetes and cardiovascular disease. Brown adipose tissue (BAT) dissipates energy and correlates with leanness. Natriuretic pept

Externí odkaz: https://doaj.org/article/e9f6437375d8496da2c195cb7ad676be

Divergent effects of a designer natriuretic peptide CD-NP in the regulation of adipose tissue and metabolism

Autor: Ana Kilić, Thorsten Gnad, John C. Burnett, Valentina Cannone, Jennifer Naumann, Anja Glöde, Alexander Pfeifer

Publikováno v: Molecular Metabolism, Vol 6, Iss 3, Pp 276-287 (2017)
Molecular Metabolism

Objective Obesity is defined as an abnormal increase in white adipose tissue (WAT) and is a major risk factor for type 2 diabetes and cardiovascular disease. Brown adipose tissue (BAT) dissipates energy and correlates with leanness. Natriuretic pepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf1653d58d65e035eea50d610f913c3
http://www.sciencedirect.com/science/article/pii/S2212877816302125

Effect of the addition of a mental health specialist for evaluation of undiagnosed patients in centres for rare diseases (ZSE-DUO): a prospective, controlled trial with a two-phase cohort designResearch in context

Autor: Helge Hebestreit, Anne-Marie Lapstich, Lilly Brandstetter, Christian Krauth, Jürgen Deckert, Kirsten Haas, Lisa Pfister, Stefanie Witt, Christopher Schippers, Jan Dieris-Hirche, Tim Maisch, Oliver Tüscher, Lavinia Bârlescu, Alexandra Berger, Mark Berneburg, Vanessa Britz, Anna Deibele, Holm Graeßner, Harald Gündel, Gereon Heuft, Thomas Lücke, Christine Mundlos, Julia Quitmann, Frank Rutsch, Katharina Schubert, Jörg Bernhard Schulz, Susann Schweiger, Cornelia Zeidler, Lena Zeltner, Martina de Zwaan, Federica Akkaya, Christine Babka, Lisa Bannert, Anja Bärsch-Michelmann, Leonie Böhm, Folke Brinkmann, Monika Bullinger, Holger Cario, Moritz de Greck, Klaus-Michael Debatin, Katrin Dillmann-Jehn, Jutta Eymann, Julia Frisch, Anja Glode, Vega Gödecke, Corinna Grasemann, Eva Grauer, Astrid Haas, Lea Haisch, Isabell, Heinrich, Melissa Held, Julia Hennermann, Stephan Herpertz, Anne Herrmann-Werner, Julian Hett, Peter Heuschmann, Bettina Hilbig, Laura Holthöfer, Christiane Imhof, Florian Junne, Jan Kassubek, Kevin-Thomas Koschitzki, Heike Krassort, Birgit Kropff, Julia Kuhn, Philipp Latzko, Thomas Loew, Albert C. Ludolph, Torsten Meyer, Isabell Meyer dos Santos, Klaus Mohnike, Martina Monninger, Martin Mücke, Susanne Müller, Thomas Musacchio, Margret Nießen, Mariel Nöhre, Stephan Ott, Andrea Petermann-Meyer, Christina Pfeifer-Duck, Lea-Sophie Piduhn, Carina Rampp, Olaf Rieß, Kristina Schaubert, Annika Schmidt, Simone Schneider, Ludger Schoels, Martina Schwalba, Udo Selig, Alexandra Sroka, Toni Steinbüchel, Sebastian Stösser, Steffi Suchant, Kathrin Ungethüm, Matthias Vogel, Daniela Volk, Christoph Vollmuth, Solange Volnov, Thomas O.F. Wagner, Sabrina Walter, Bodo Warrings, Kamil Zajt, Karola Zenker, David Zhang, Stephan Zipfel, Lavinia Aurelia Bârlescu, Julia Hannah Quitmann, Jörg B. Schulz, Lena Margarete Zeltner

Publikováno v: EClinicalMedicine, Vol 65, Iss , Pp 102260- (2023)

Summary: Background: People with complex symptomatology but unclear diagnosis presenting to a centre for rare diseases (CRD) may present with mental (co-)morbidity. We hypothesised that combining an expert in somatic medicine with a mental health spe

Externí odkaz: https://doaj.org/article/7104fbd316dd40be90da99c4bb8c26c0

Direct lentivirus injection for fast and efficient gene transfer into brown and beige adipose tissue

Autor: Katarina Klepac, Linda S. Hoffmann, Aileen Balkow, Thorsten Gnad, Katrin Zimmermann, Anja Glöde, Alexander Pfeifer

Publikováno v: Journal of Biological Methods

Brown adipose tissue is a special type of fat contributing to energy expenditure in human newborns and adults. Moreover, subcutaneous white adipose tissue has a high capacity to adapt an energy-consuming, brown-like/beige phenotype. Here, we develope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d72033f6addbffec528cc126b719ed
https://doi.org/10.14440/jbm.2016.123

Adenosine activates brown adipose tissue and recruits beige adipocytes via A(2A) receptors

Autor: Matthias J. Betz, Thorsten Gnad, Laia Reverte-Salisa, Christa E. Müller, Samet Mutlu, Jürgen Schrader, Philipp Horn, Ivar von Kügelgen, Alexander Pfeifer, Ali El-Tayeb, Saskia Scheibler, Sven Enerbäck, Anja Glöde, Mathias Kranz, Linda S. Hoffmann, Winnie Deuther-Conrad, Peter Brust, Camilla Scheele, Gennady G. Yegutkin, Martin E. Lidell, Ana Kilić

Publikováno v: Nature. 516(7531):395

Brown adipose tissue (BAT) is specialized in energy expenditure, making it a potential target for anti-obesity therapies. Following exposure to cold, BAT is activated by the sympathetic nervous system with concomitant release of catecholamines and ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b52923d7ef660a033095b5ee2e42be
http://juuli.fi/Record/0252482514