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Introduction to the EQIPD quality system

Autor: Lior Bikovski, Raafat Fares, Anton Bespalov, Claudia Kurreck, Leonardo Restivo, Paul Moser, Chantelle Ferland-Beckham, Claudia Stöger, Patricia Kabitzke, Ernesto Prado Montes de Oca, Bruce Altevogt, Valerie Gailus-Durner, Sabine M. Hölter, Piotr Popik, Martine C J Hofmann, Vootele Voikar, Lee Monk, Michael Schunn, Alexander Dityatev, Janko Samardzic, Gernot Riedel, Thomas Steckler, Natasja de Bruin, Merel Ritskes-Hoitinga, Kathleen Wuyts, Christoph H. Emmerich, Heidrun Potschka, Vincent Castagné, Christelle Froger-Colléaux, Fiona Ducrey, Anja Gilis, Björn Gerlach, Jan Vollert, Kimberley E. Wever, Sandrine Bongiovanni, Esmeralda Castaños-Vélez, Martien J H Kas, René Bernard, Malcolm R. Macleod, Isabel A Lefevre, Javier Guillén, Małgorzata Pietraszek, María Arroyo-Araujo, Ulrich Dirnagl

Publikováno v: Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-araujo, M, Bikovski, L, De Bruin, N, Castaños-vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-beckham, C, Froger-colléaux, C, Gailus-durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes De Oca, E, Restivo, L, Riedel, G, Ritskes-hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, Macleod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLIFE, vol. 10 . https://doi.org/10.7554/eLife.63294
eLife, 10:e63294. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 10 (2021)
eLife 10, e63294 (2021). doi:10.7554/eLife.63294
eLife
Elife, 10
Bespalov, A, Bernard, R, Gilis, A, Gerlach, B, Guillén, J, Castagné, V, Lefevre, I A, Ducrey, F, Monk, L, Bongiovanni, S, Altevogt, B, Arroyo-Araujo, M, Bikovski, L, de Bruin, N, Castaños-Vélez, E, Dityatev, A, Emmerich, C H, Fares, R, Ferland-Beckham, C, Froger-Colléaux, C, Gailus-Durner, V, Hölter, S M, Hofmann, M C, Kabitzke, P, Kas, M J, Kurreck, C, Moser, P, Pietraszek, M, Popik, P, Potschka, H, Prado Montes de Oca, E, Restivo, L, Riedel, G, Ritskes-Hoitinga, M, Samardzic, J, Schunn, M, Stöger, C, Voikar, V, Vollert, J, Wever, K E, Wuyts, K, MacLeod, M R, Dirnagl, U & Steckler, T 2021, ' Introduction to the EQIPD quality system ', eLife, vol. 10, e63294 . https://doi.org/10.7554/eLife.63294
eLife, vol. 10, pp. e63294

While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Numerous analyses conducted to date have clearly identified measures that need to be take

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aef7c0ead5b242adb59f95192215766
http://hdl.handle.net/10044/1/95909

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Systematic review of guidelines for internal validity in the design, conduct and analysis of preclinical biomedical experiments involving laboratory animals

Autor: Merel Ritskes-Hoitinga, Ulrich Dirnagl, Malcolm Macleod, Thomas Steckler, Jan Vollert, Esther Schenker, Anton Bespalov, Hanno Wuerbel, Heidrun Potschka, Kimberley E Wever, Bruce Altevogt, Andrew S C Rice, Judi Clark, Emily Sena, Bruno Boulanger, Gernot Riedel, Bettina Platt, Annesha Sil, Martien J Kas, Bernhard Voelkl, Mathias Jucker, Bettina M Wegenast-braun, René Bernard, Esmeralda Heiden, Ann-marie Waldron, Maarten Loos, Pim Drinkenburg, Juan Diego Pita almenar, David Gallacher, Anja Gilis, Greet Teuns, Karsten Wicke, Sabine Grote, Bernd Sommer, Janet Nicholson, Sanna Janhunen, Sami Virtanen, Kristin Cheng, Sylvie Ramboz, Emer Leahy, Isabel A Lefevre, Fiona Ducrey, Javier Guillen, Patri Vergara, Kimberley Wever, Martin Michel, Tom van de Casteele, Martin C Michel, Tom Van De Casteele, Henk Van Der Linde, Isabel Seiffert

Publikováno v: BMJ Open Science, Vol 4, Iss 1 (2020)

Over the last two decades, awareness of the negative repercussions of flaws in the planning, conduct and reporting of preclinical research involving experimental animals has been growing. Several initiatives have set out to increase transparency and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::f3c843a32daac53e6720e2c19b3ead99
https://openscience.bmj.com/content/4/1/e100046.full

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Quality Governance in Biomedical Research

Autor: Anja Gilis

Publikováno v: Handbook of Experimental Pharmacology
Handbook of Experimental Pharmacology-Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Good Research Practice in Non-Clinical Pharmacology and Biomedicine ISBN: 9783030336554
Good Research Practice in Non-Clinical Pharmacology and Biomedicine

Quality research data are essential for quality decision-making and thus for unlocking true innovation potential to ultimately help address unmet medical needs.The factors influencing quality are diverse. They depend on institution type and experimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9b74a30031b1ba8ea3818ad3e1f24f
https://pubmed.ncbi.nlm.nih.gov/31628603

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Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals

Publikováno v: BMJ Open Science
BMJ Open Science, Vol 2, Iss 1 (2018)
Vollert, J, Schenker, E, Macleod, M, Bespalov, A, Wuerbel, H, Michel, M C, Dirnagl, U, Potschka, H, Wever, K E, Steckler, T, Altevogt, B & Rice, A S C 2018, ' Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals ', BMJ Open Science, vol. 2, no. 1, pp. e000004 . https://doi.org/10.1136/bmjos-2018-000004
Vollert, Jan; Schenker, Esther; Macleod, Malcolm; Bespalov, Anton; Würbel, Hanno; Michel, Martin Christian; Dirnagl, Ulrich; Potschka, Heidrun; Wever, Kimberley E; Steckler, Thomas; Altevogt, Bruce; Rice, Andrew S C (2018). Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals. BMJ open science, 2(1), e000004. BMJ Publishing Group 10.1136/bmjos-2018-000004

Objective Within the last years, there has been growing awareness of the negative repercussions of unstandardized planning, conduct and reporting of preclinical and biomedical research. Several initiatives have set the aim of increasing validity and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45451d537d3977c8a94faa520489db09

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Evidence that Ralstonia eutropha (Alcaligenes eutrophus) contains a functional homologue of the Ralstonia solanacearum Phc cell density sensing system

Autor: Timothy P. Denny, Daniel Van Der Lelie, Mark A. Schell, Wandee Yindeeyoungyeon, Anja Gilis, Ram P. Garg

Publikováno v: Molecular Microbiology. 38:359-367

In the phytopathogen Ralstonia (Pseudomonas) solanacearum, control of many virulence genes is partly mediated by the Phc cell density sensing system. Phc uses a novel self-produced signal molecule [3-hydroxypalmitic acid methyl ester (3-OH PAME)], an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290270d5a654840ccabdbf2889b43f65
https://doi.org/10.1046/j.1365-2958.2000.02131.x

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The Role of Bacteria in the Phytoremediation of Heavy Metals

Autor: S. Taghavi, P. Corbisier, Cindy Lodewyckx, Anja Gilis, Ludo Diels, Nele Spelmans, M. Mergeay, Jaco Vangronsveld, D. van der Lelie

Publikováno v: Phytoremediation of contaminated soils and water / Terry, N. [edit.]

This chapter discusses the potential impact of soil bacteria on heavy metal extraction by plants. Rhizosphere bacteria, including those which carry plasmid-borne resistances to heavy metals, may be expected to play an important role in the bioavailab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6275e0baa5256ca95435eab60c3f410b
https://doi.org/10.1201/9781439822654.ch15

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Effect of the siderophore alcaligin E on the bioavailability of Cd to Alcaligenes eutrophus CH34

Autor: D. van der Lelie, P. Corbisier, Wilfried Baeyens, Max Mergeay, Safieh Taghavi, Anja Gilis

Publikováno v: Journal of industrial microbiologybiotechnology. 20(1)

Alcaligin E, the siderophore of the heavy metal-resistant A. eutrophus strain CH34, was shown to interact with Cd and consequently affect its bioavailability and toxicity. The addition of alcaligin E markedly stimulated the growth in the presence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11f1da44ffddba93746345a74f0e312
https://pubmed.ncbi.nlm.nih.gov/9523457

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