Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anja Fromm"'
Autor:
Julian Friebel, Katina Schinnerling, Kathleen Weigt, Claudia Heldt, Anja Fromm, Christian Bojarski, Britta Siegmund, Hans-Jörg Epple, Judith Kikhney, Annette Moter, Thomas Schneider, Jörg D. Schulzke, Verena Moos, Michael Schumann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6197 (2023)
Background: Tropheryma whipplei (TW) can cause different pathologies, e.g., Whipple’s disease and transient gastroenteritis. The mechanism by which the bacteria pass the intestinal epithelial barrier, and the mechanism of TW-induced gastroenteritis
Externí odkaz:
https://doaj.org/article/0940836fb38b41fd938b25f16b6f62c4
Autor:
Emanuel Schulz, Michael Schumann, Martina Schneemann, Violaine Dony, Anja Fromm, Oliver Nagel, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
Toxins, Vol 13, Iss 8, p 520 (2021)
Escherichia coli (E. coli) of the B2 phylotype reside in human and animal intestines. The bacteria possess pathogenicity factors such as α-hemolysin (HlyA) that can induce intestinal epithelial leaks. We addressed the questions which host cell proce
Externí odkaz:
https://doaj.org/article/e0cbc6bbc7074459af600ccc69d43ff4
Autor:
Praveen Kumar Nattramilarasu, Roland Bücker, Fábia Daniela Lobo de Sá, Anja Fromm, Oliver Nagel, In-Fah Maria Lee, Eduard Butkevych, Soraya Mousavi, Claudia Genger, Sigri Kløve, Markus M. Heimesaat, Stefan Bereswill, Michal R. Schweiger, Hans Linde Nielsen, Hanno Troeger, Jörg-Dieter Schulzke
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 373 (2020)
The epithelial sodium channel (ENaC) can increase the colonic absorptive capacity for salt and water. Campylobacter concisus is a common pathogenic epsilonproteobacterium, causing enteritis and diarrhea. It can induce barrier dysfunction in the intes
Externí odkaz:
https://doaj.org/article/5590e5f6e03444fbac97aaba9e5c83ff
Autor:
Nina A. Hering, Anja Fromm, Roland Bücker, Gregor Gorkiewicz, Ellen Zechner, Christoph Högenauer, Michael Fromm, Jörg-Dieter Schulzke, Hanno Troeger
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5595 (2019)
Klebsiella oxytoca causes antibiotic-associated hemorrhagic colitis and diarrhea. This was attributed largely to its secreted cytotoxins tilivalline and tilimycin, inductors of epithelial apoptosis. To study whether Klebsiella oxytoca exerts further
Externí odkaz:
https://doaj.org/article/13822ed3d9624a3a83b3dd3a37f61350
Autor:
Joakim Klar, Jörg Piontek, Susanne Milatz, Muhammad Tariq, Muhammad Jameel, Tilman Breiderhoff, Jens Schuster, Ambrin Fatima, Maria Asif, Muhammad Sher, Katrin Mäbert, Anja Fromm, Shahid M Baig, Dorothee Günzel, Niklas Dahl
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006897 (2017)
Claudins constitute the major component of tight junctions and regulate paracellular permeability of epithelia. Claudin-10 occurs in two major isoforms that form paracellular channels with ion selectivity. We report on two families segregating an aut
Externí odkaz:
https://doaj.org/article/9f1d2c00083340ffb2f3e2563a417363
Autor:
Fábia Daniela Lobo de Sá, Eduard Butkevych, Praveen Kumar Nattramilarasu, Anja Fromm, Soraya Mousavi, Verena Moos, Julia C. Golz, Kerstin Stingl, Sophie Kittler, Diana Seinige, Corinna Kehrenberg, Markus M. Heimesaat, Stefan Bereswill, Jörg-Dieter Schulzke, Roland Bücker
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4830 (2019)
Campylobacter jejuni (C. jejuni) is the most common cause of foodborne gastroenteritis worldwide. The bacteria induce diarrhea and inflammation by invading the intestinal epithelium. Curcumin is a natural polyphenol from turmeric rhizome of Curcuma l
Externí odkaz:
https://doaj.org/article/3ca7c2ee21034dd886b183e87d348013
Autor:
Dana Kuntzsch, Theresa Bergann, Petra Dames, Anja Fromm, Michael Fromm, Rohan A Davis, Matthias F Melzig, Joerg D Schulzke
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49426 (2012)
In a search for secondary plant compounds that bind to the glucocorticoid receptor (GR), the cyclobutane lignan endiandrin A was discovered from the rainforest tree Endiandra anthropophagorum Domin. Our present study aims to characterize the effect o
Externí odkaz:
https://doaj.org/article/6195fe6796c545c2af4270a22eee55dc
Anti-diarrheal mechanism of the traditional remedy Uzara via reduction of active chloride secretion.
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18107 (2011)
BACKGROUND AND PURPOSE: The root extract of the African Uzara plant is used in traditional medicine as anti-diarrheal drug. It is known to act via inhibition of intestinal motility, but malabsorptive or antisecretory mechanisms are unknown yet. EXPER
Externí odkaz:
https://doaj.org/article/9736e4453a9a4d75bd11bf858fea3aa8
Autor:
Caroline Hempel, Rita Rosenthal, Anja Fromm, Susanne M. Krug, Michael Fromm, Dorothee Günzel, Jörg Piontek
Publikováno v:
Annals of the New York Academy of SciencesREFERENCES. 1515(1)
Although functional and structural models for paracellular channels formed by claudins have been reported, mechanisms regulating charge and size selectivity of these channels are unknown in detail. Here, claudin-15 and claudin-10b cation channels sho
Autor:
Tilman Breiderhoff, Nina Himmerkus, Luca Meoli, Anja Fromm, Sebastian Sewerin, Natalia Kriuchkova, Oliver Nagel, Yury Ladilov, Susanne M. Krug, Catarina Quintanova, Meike Stumpp, Dieter Garbe-Schönberg, Ulrike Westernströer, Cosima Merkel, Merle Annette Brinkhus, Janine Altmüller, Michal R. Schweiger, Dominik Müller, Kerim Mutig, Markus Morawski, Jan Halbritter, Susanne Milatz, Markus Bleich, Dorothee Günzel
Publikováno v:
J Am Soc Nephrol
BACKGROUND: The tight junction proteins claudin-2 and claudin-10a form paracellular cation and anion channels, respectively, and are expressed in the proximal tubule. However, the physiological role of claudin-10a in the kidney has been unclear. METH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ef4fb7feb05c65ea38cecf07a2b956
http://edoc.mdc-berlin.de/21260/7/21260suppl.xlsx
http://edoc.mdc-berlin.de/21260/7/21260suppl.xlsx