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Autor:
Mirko Buchholz, Holger Cynis, Hans-Ulrich Demuth, Claudia Spahn, Ulrike Zeitschel, Daniel Ramsbeck, Michael Wermann, Maike Hartlage-Rübsamen, Steffen Roßner, Katja Menge, Dagmar Schlenzig, Anja Fothe, Stephan Schilling
Publikováno v:
Journal of Alzheimer's Disease. 66:359-375
The formation of amyloid-β (Aβ) peptides is causally involved in the development of Alzheimer's disease (AD). A significant proportion of deposited Aβ is N-terminally truncated and modified at the N-terminus by a pGlu-residue (pGlu-Aβ). These for