Výsledky vyhledávání

Cardiac troponin T is elevated and increases longitudinally in ALS patients

Autor: Henrik Zetterberg, Rayomand Press, Qing Shen, Björn Evertsson, Sanharib Chamoun, Caroline Ingre, Anna Månberg, Kaj Blennow, Fang Fang, Anja Finn, Kristin Samuelsson, Ulf Kläppe

Publikováno v: Amyotrophic lateral sclerosisfrontotemporal degeneration. 23(1-2)

Objective: To test whether high-sensitivity cardiac troponin T (hs-cTnT) could act as a diagnostic or prognostic biomarker in ALS, comparing hs-cTnT to neurofilament light (NfL). Methods: We performed a case-control study, including 150 ALS patients,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9428302475ae4e4e4fcd1a331969af
https://pubmed.ncbi.nlm.nih.gov/34151677

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Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease

Autor: Svante Berg, Eva Kosek, Camilla I. Svensson, Aisha Siddiqah Ahmed, Anja Finn, Vinko Palada

Publikováno v: Brain, Behavior, and Immunity. 75:60-71

The aim of the study was to identify inflammatory cytokines/chemokines associated with neuroinflammation and periphery-to-CNS inflammatory cross-talk in degenerative disc disease (DDD) and lumbar disc herniation (LDH), common causes of low back pain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c98b08fa0516d1db69ddf6dd09d7cae
https://doi.org/10.1016/j.bbi.2018.09.010

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Differences in neuroimmune signalling between male and female patients suffering from knee osteoarthritis

Autor: Camilla I. Svensson, Aisha Siddiqah Ahmed, Anja Finn, Anders Hugo, C. Ultenius, Eva Kosek

Publikováno v: Journal of Neuroimmunology. 321:49-60

The primary aim was to identify cytokines involved in blood borne, neuroimmune joint-to-CNS signalling in knee osteoarthritis (OA) patients. Monocyte chemoattractant protein 1 (MCP1) and Interleukin-8 (IL-8) were elevated in the cerebrospinal fluid (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1286e717cee66f194d07d17bb56788c7
https://doi.org/10.1016/j.jneuroim.2018.05.009

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No evidence for altered plasma NGF and BDNF levels in fibromyalgia patients

Autor: Wolfgang Eich, Anja Finn, Jonas Tesarz, David Baumeister, Olga Geisel, Silvia Saft, Camilla I. Svensson, Rainer Hellweg

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-5 (2019)
Scientific Reports

There has been a surging interest in the putative role of peripheral growth factors in the pathophysiology of fibromyalgia, specifically in the peripheral sensitization that occurs in chronic pain disorders. This cross-sectional study set out to asse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5ea4e5256c5796e932954cc74299dd
https://doi.org/10.1038/s41598-019-49403-7

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Autoantibodies to citrullinated proteins may induce joint pain independent of inflammation

Publikováno v: Annals of the Rheumatic Diseases. 75:730-738

ObjectiveAn interesting and so far unexplained feature of chronic pain in autoimmune disease is the frequent disconnect between pain and inflammation. This is illustrated well in rheumatoid arthritis (RA) where pain in joints (arthralgia) may precede

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3a9fbe004c6c60c8e38c030a970c0f9
https://doi.org/10.1136/annrheumdis-2015-208094

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Using gait analysis to assess weight bearing in rats with Freund׳s complete adjuvant-induced monoarthritis to improve predictivity: Interfering with the cyclooxygenase and nerve growth factor pathways

Autor: Camilla I. Svensson, Kristina Ängeby Möller, Carina Stenfors, Odd-Geir Berge, Anja Finn

Publikováno v: European Journal of Pharmacology. 756:75-84

Lack of predictive power for drug effects has been a major criticism against animal pain models. It is therefore important to define the utility and limitations of different models. The aim of this study was to extend previous work on gait analysis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2ccb442688107de53e7bc53d1b03ab
https://doi.org/10.1016/j.ejphar.2015.02.050

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Evidence of different mediators of central inflammation in dysfunctional and inflammatory pain — Interleukin-8 in fibromyalgia and interleukin-1 β in rheumatoid arthritis

Autor: Mats Jensen-Urstad, Reem Altawil, Magnus Andersson, Jon Lampa, Anja Finn, Diana Kadetoff, Erwan Le Maître, Marie Westman, Eva Kosek

Publikováno v: Journal of Neuroimmunology

The purpose of this study was to relate central inflammation to autonomic activity (heart rate variability (HRV)) in patients with rheumatoid arthritis (RA) and fibromyalgia (FM). RA patients had reduced parasympathetic activity and FM patients had i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c555f3c51fe3e0f899845f352a07ff8

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Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers

Autor: Zsuzsanna Wiesenfeld-Hallin, Ulf Eriksson, Jacob Kjell, Camilla I. Svensson, Lars Olson, Anna Josephson, Mathew Abrams, Katrin Wellfelt, Anja Finn, Jing-Xia Hao

Publikováno v: Journal of Neurotrauma

With no currently available drug treatment for spinal cord injury, there is a need for additional therapeutic candidates. We took the approach of repositioning existing pharmacological agents to serve as acute treatments for spinal cord injury and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc4822b4fb07c65ef17da44da8b5213
http://europepmc.org/articles/PMC4752188

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Influence of model and matrix on cytokine profile in rat and human

Autor: Charlotte Gustafsson, Anja Finn, Gunnar Nordahl, Mats Ferm, Camilla I. Svensson, Sally Abdelmoaty, Kristina Ängeby Möller

Publikováno v: Rheumatology. 53:2297-2305

Objective Emerging evidence indicates that low-grade inflammation is part of the clinical picture of OA and that there is a need to identify soluble biomarkers of ongoing inflammation in the joint from a translational aspect. The aim of this study wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cc9e606d69ae5663494c763e935820
https://doi.org/10.1093/rheumatology/keu281

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