Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anja E. Eisenhardt"'
Autor:
David Braig, Alexander Runkel, Anja E. Eisenhardt, Adrian Schmid, Johannes Zeller, Thomas Pauli, Ute Lausch, Julius Wehrle, Peter Bronsert, Matthias Jung, Jurij Kiefer, Melanie Boerries, Steffen U. Eisenhardt
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10215
Soft tissue sarcomas (STS) are rare tumors of mesenchymal origin with high mortality. After curative resection, about one third of patients suffer from distant metastases. Tumor follow-up only covers a portion of recurrences and is associated with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6577bf99724ad9a4895b47b691748969
https://pubmed.ncbi.nlm.nih.gov/36142126
https://pubmed.ncbi.nlm.nih.gov/36142126
Autor:
Anja E. Eisenhardt, Zacharias Brugger, Ute Lausch, Jurij Kiefer, Johannes Zeller, Alexander Runkel, Adrian Schmid, Peter Bronsert, Julius Wehrle, Andreas Leithner, Bernadette Liegl-Atzwanger, Riccardo E. Giunta, Steffen U. Eisenhardt, David Braig
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2078
Background: Synovial sarcoma (SS) is a malignant soft tissue tumor of mesenchymal origin that frequently occurs in young adults. Translocation of the SYT gene on chromosome 18 to the SSX genes on chromosome X leads to the formation of oncogenic fusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3574ecd5b75ced6a146b89ae0757e2
Autor:
Steffen U. Eisenhardt, Alba Fricke, Georg W. Herget, Jutta Scholber, Holger Bannasch, Peter Bronsert, Christiane Bickert, Anja E. Eisenhardt, Marie Follo, Rainer Claus, David Braig, G. Bjoern Stark, Juergen Heinz, Moritz Braig, Caroline Becherer
Soft tissue sarcomas (STS) are rare tumors of mesenchymal origin. About 50% of patients with STS experience relapse and more than 30% will die within 10 years after diagnosis. In this study we investigated circulating free DNA (cfDNA) and tumor-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360c2c3004606f2a10859039dc490ced
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/58460
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/58460
Autor:
Anja E. Eisenhardt, Ricarda Herr, Gina J. Fiala, Sebastian Halbach, Michael Röring, David Capper, Katharina Heilmann, Wolfgang W. A. Schamel, Sandra Braun, Tilman Brummer, Darren N. Saunders, Andreas von Deimling
Publikováno v:
The EMBO Journal. 31:2629-2647
The dimerisation of Raf kinases involves a central cluster within the kinase domain, the dimer interface (DIF). Yet, the importance of the DIF for the signalling potential of wild-type B-Raf (B-Raf(wt)) and its oncogenic counterparts remains unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::409e5bfd895aa0de0e1d8ca8a6e57562
https://doi.org/10.1038/emboj.2012.100
https://doi.org/10.1038/emboj.2012.100
Autor:
Wolfgang W. A. Schamel, Lisa C. Schmitt, Anja Meyer, Anja E. Eisenhardt, Sumit Deswal, Oreste Acuto, Tilman Brummer, Gina J. Fiala, Mogjiborahman Salek
Publikováno v:
The Journal of Immunology; Vol 190
The Journal of Immunology
The Journal of Immunology
The activation kinetics of MAPK Erk are critical for T cell development and activation. In particular, sustained Erk signaling is required for T cell activation and effector functions, such as IL-2 production. Although Raf-1 triggers transient Erk ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c015c664512309041d7f8206ec8c1c7e
https://pubmed.ncbi.nlm.nih.gov/23359496
https://pubmed.ncbi.nlm.nih.gov/23359496
Autor:
Andrey Korshunov, Huriye Cin, Tilman Brummer, Wibke G. Janzarik, Hendrik Witt, Anja E. Eisenhardt, Ton Nu Van Anh, Heymut Omran, Stefan M. Pfister, Marc Remke, Heike Olbrich, Michael Röring
Publikováno v:
International journal of cancer. 129(9)
Pilocytic astrocytoma (PA) is emerging as a tumor entity with dysregulated Ras/Raf/MEK/ERK signaling. Common genetic lesions observed in PA, which are linked to aberrant ERK pathway activity, include either NF1 inactivation, KRAS or BRAF gain-of-func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b93233bbdc2eaf5da79702dd270a7d3
https://pubmed.ncbi.nlm.nih.gov/21190184
https://pubmed.ncbi.nlm.nih.gov/21190184