Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anja Dölle"'
Autor:
Martin P. Schwalm, Andreas Krämer, Anja Dölle, Janik Weckesser, Xufen Yu, Jian Jin, Krishna Saxena, Stefan Knapp
The multistep PROTAC (PROteolysis TArgeting Chimeras) degradation process poses challenges for their rational development, as rate limiting steps determining PROTAC efficiency remain largely unknown. Moreover, the slow throughput of currently used en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80077b70c79e7ef0e64344b2fba8ddc8
https://doi.org/10.1101/2023.01.11.523589
https://doi.org/10.1101/2023.01.11.523589
Autor:
Andreas Krämer, Elmar Wolf, Frank Löhr, Dalia Barsyte-Lovejoy, Martin Eilers, Mathias Diebold, Magdalena M. Szewczyk, Christoph A. Sotriffer, Cheryl H. Arrowsmith, Lena-Marie Berger, Stephanie Heinzlmeir, Jakob Gebel, Bernhard Kuster, Volker Dötsch, Stefan Knapp, Bikash Adhikari, Anja Dölle, Janik Weckesser, Nicola Berner
Publikováno v:
Journal of Medicinal Chemistry
Histone H3K4 methylation serves as a post-translational hallmark of actively transcribed genes and is introduced by histone methyltransferase (HMT) and its regulatory scaffolding proteins. One of these is the WD-repeat-containing protein 5 (WDR5) tha