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pro vyhledávání: '"Anja Charlotte Lundgren Mortensen"'
Autor:
Anja Charlotte Lundgren Mortensen, Hanna Berglund, Mehran Hariri, Eleftherios Papalanis, Christer Malmberg, Diana Spiegelberg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Thyroid cancer is the most common endocrine malignancy, affecting nearly 600,000 new patients worldwide. Treatment with the BRAF inhibitor sorafenib partially prolongs progression-free survival in thyroid cancer patients, but fails to improv
Externí odkaz:
https://doaj.org/article/1b59be93ecd2470187a1d6c7f8418bf4
Autor:
Diana Spiegelberg, Anja Charlotte Lundgren Mortensen, Kartika Dyah Palupi, Patrick Micke, Julin Wong, Borivoj Vojtesek, David Philip Lane, Marika Nestor
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
RationalcMet is abnormally regulated in gastrointestinal cancer, and is associated with increased invasiveness of the disease and poor overall survival. There are indications that targeted therapy against cMet, alone or in combination with additional
Externí odkaz:
https://doaj.org/article/5432d99071b24b57adc1dde95164618e
Autor:
Anja Charlotte Lundgren Mortensen, Tabassom Mohajershojai, Mehran Hariri, Marika Pettersson, Diana Spiegelberg
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
RationalCisplatin based cancer therapy is an affordable and effective standard therapy for several solid cancers, including lung, ovarian and head and neck cancers. However, the clinical use of cisplatin is routinely limited by the development of dru
Externí odkaz:
https://doaj.org/article/fb1832a87a074e8f858bb39f6f985b28
Autor:
Anja Charlotte Lundgren Mortensen, Diana Spiegelberg, Christopher John Brown, David Philip Lane, Marika Nestor
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The tumor suppressor p53 is a key mediator of cellular stress and DNA damage response cascades and is activated after exposure to ionizing radiation. Amplifying wild-type p53 expression by targeting negative regulators such as MDM2 in combination wit
Externí odkaz:
https://doaj.org/article/625d8ae824cf4fb8841b5f0c06ec12c1