Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anja Bukovac"'
Autor:
Anja Kafka, Nives Pećina-Šlaus, Denis Drmić, Anja Bukovac, Niko Njirić, Kamelija Žarković, Antonia Jakovčević
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionEpigenetics play a vital role in stratifying CNS tumors and gliomas. The importance of studying Secreted frizzled-related protein 4 (SFRP4) in gliomas is to improve diffuse glioma methylation profiling. Here we examined the methylation st
Externí odkaz:
https://doaj.org/article/0d72b10c58e248758d2f257d6be37a4e
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-15 (2023)
Abstract This review presents current knowledge on the molecular biology of retinoblastoma (RB). Retinoblastoma is an intraocular tumor with hereditary and sporadic forms. 8,000 new cases of this ocular malignancy of the developing retina are diagnos
Externí odkaz:
https://doaj.org/article/b091560262d54b2b9420b45a803ed5c5
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The acquisition of genomic instability is one of the key characteristics of the cancer cell, and microsatellite instability (MSI) is an important segment of this phenomenon. This review aims to describe the mismatch DNA repair (MMR) system whose defi
Externí odkaz:
https://doaj.org/article/5f58b7bc39974863bad4e1cc28d4a21e
Publikováno v:
Tumor Biology, Vol 39 (2017)
Postreplicative mismatch repair safeguards the stability of our genome. The defects in its functioning will give rise to microsatellite instability. In this study, 50 meningiomas were investigated for microsatellite instability. Two major mismatch re
Externí odkaz:
https://doaj.org/article/b7a26197cb17443982c9691173ca0c63
In a continuous search for the improvement of antitumor therapies, the inhibition of the Wnt signaling pathway has been recognized as a promising target. The altered functioning of the Wnt signaling in human tumors points to the strategy of the inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149689523228696b379b3c68bb085c3a
https://www.bib.irb.hr/1265220
https://www.bib.irb.hr/1265220
Autor:
Anja Bukovac, Hana Panić, Tomislava Mrgan, Nika Šlaus, Anja Kafka, Niko Njirić, Nives Pećina-Šlaus
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1187, p 1187 (2022)
Here, we present a rarely seen example of bilateral meningiomas exhibiting different malignancy grades, I (meningothelial) and II (atypical), recorded in a 72-year-old patient. The presence of two separated lesions of different grades in a single pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5624c2b4ece1fb7be5253f5f8cdab375
https://doi.org/10.3390/ijms23031187
https://doi.org/10.3390/ijms23031187
Publikováno v:
Cancers
Volume 13
Issue 13
Cancers, Vol 13, Iss 3247, p 3247 (2021)
Volume 13
Issue 13
Cancers, Vol 13, Iss 3247, p 3247 (2021)
Simple Summary The current classification of central nervous system tumors has incorporated molecular changes that have clarified biological behavior and categorized gliomas into different types and malignancy grades. The most malignant type—gliobl
Autor:
Anja Kafka, Kamelija Žarković, Ana-Marija Jarmek, Karolina Poljak, Niko Njirić, Emilija Brglez, Petar Brlek, Anja Bukovac, Nives Pećina-Šlaus
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2530, p 2530 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2530, p 2530 (2021)
In the present study, we investigated genetic and epigenetic changes and protein expression levels of negative regulators of Wnt signaling, DKK1, DKK3, and APC as well as glycogen synthase kinase 3 (GSK3β) and β-catenin in 64 human astrocytomas of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eebee4fb9e0d46edc011fde7125afc6
https://urn.nsk.hr/urn:nbn:hr:105:337868
https://urn.nsk.hr/urn:nbn:hr:105:337868
Autor:
Anja, Kafka, Anja, Bukovac, Emilija, Brglez, Ana-Marija, Jarmek, Karolina, Poljak, Petar, Brlek, Kamelija, Žarković, Niko, Njirić, Nives, Pećina-Šlaus
Publikováno v:
Cancers
Simple Summary Astrocytomas are the most common type of primary brain tumor in adults. In this study, 64 astrocytoma samples of grades II–IV were analyzed for genetic and epigenetic changes as well as protein expression patterns in order to explore
Autor:
Anja Kafka, Katarina Dragičević, Danko Müller, Marina Raguž, Anja Bukovac, Nives Pećina-Šlaus, Petar Brlek
Publikováno v:
Cancers, Vol 13, Iss 1633, p 1633 (2021)
Cancers
Volume 13
Issue 7
Cancers
Volume 13
Issue 7
Simple Summary Intracranial meningiomas are one of the most common primary brain tumors. Although mostly benign, a small portion may exhibit aggressive and malignant characteristics leading to higher recurrence and mortality rate. Detecting the molec