Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Anja Bubke"'
Autor:
Georg M. N. Behrens, Joana Barros-Martins, Anne Cossmann, Gema Morillas Ramos, Metodi V. Stankov, Ivan Odak, Alexandra Dopfer-Jablonka, Laura Hetzel, Miriam Köhler, Gwendolyn Patzer, Christoph Binz, Christiane Ritter, Michaela Friedrichsen, Christian Schultze-Florey, Inga Ravens, Stefanie Willenzon, Anja Bubke, Jasmin Ristenpart, Anika Janssen, George Ssebyatika, Verena Krähling, Günter Bernhardt, Markus Hoffmann, Stefan Pöhlmann, Thomas Krey, Berislav Bošnjak, Swantje I. Hammerschmidt, Reinhold Förster
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Vaccines against SARS-CoV-2 have changed the course of the COVID-19 pandemics, but waning immunity necessitates repeated immunization. Authors here show that immunity declines faster following two doses of vector-based vaccine compared to a first dos
Externí odkaz:
https://doaj.org/article/f52b7c9a5c1744e8b2ee862e712fdd80
Autor:
Leon Ullrich, Yvonne Lueder, Anna-Lena Juergens, Anneke Wilharm, Joana Barros-Martins, Anja Bubke, Abdi Demera, Koichi Ikuta, Gwendolyn Elena Patzer, Anika Janssen, Inga Sandrock, Immo Prinz, Francesca Rampoldi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The mucosal immune system is the first line of defense against pathogens. Germinal centers (GCs) in the Peyer’s patches (PPs) of the small intestine are constantly generated through stimulation of the microbiota. In this study, we investigated the
Externí odkaz:
https://doaj.org/article/4cb32a24dbce4fc98e5a56dd8eee30a9
Autor:
Berislav Bošnjak, Ivan Odak, Joana Barros-Martins, Inga Sandrock, Swantje I. Hammerschmidt, Marc Permanyer, Gwendolyn E. Patzer, Hristo Greorgiev, Rodrigo Gutierrez Jauregui, Alina Tscherne, Jan Hendrik Schwarz, Georgia Kalodimou, George Ssebyatika, Malgorzata Ciurkiewicz, Stefanie Willenzon, Anja Bubke, Jasmin Ristenpart, Christiane Ritter, Tamara Tuchel, Christian Meyer zu Natrup, Dai-Lun Shin, Sabrina Clever, Leonard Limpinsel, Wolfgang Baumgärtner, Thomas Krey, Asisa Volz, Gerd Sutter, Reinhold Förster
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antigen-specific tissue-resident memory T cells (Trms) and neutralizing IgA antibodies provide the most effective protection of the lungs from viral infections. To induce those essential components of lung immunity against SARS-CoV-2, we tested vario
Externí odkaz:
https://doaj.org/article/76eb9b3576254d289905045704455f62
Autor:
Kathrin Werth, Elin Hub, Julia Christine Gutjahr, Berislav Bosjnak, Xiang Zheng, Anja Bubke, Stefan Russo, Antal Rot, Reinhold Förster
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109346- (2021)
Summary: The spleen comprises defined microanatomical compartments that uniquely contribute to its diverse host defense functions. Here, we identify a vascular compartment within the red pulp of the spleen delineated by expression of the atypical che
Externí odkaz:
https://doaj.org/article/83c32ed064fd41f389cc2cfc80319b6b
Autor:
Henrike Fleige, Berislav Bosnjak, Marc Permanyer, Jasmin Ristenpart, Anja Bubke, Stefanie Willenzon, Gerd Sutter, Sanjiv A. Luther, Reinhold Förster
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 783-795 (2018)
Summary: The processes underlying the development and maintenance of tertiary lymphoid organs are incompletely understood. Using a Ccr7 knockout/knockin approach, we show that spontaneous bronchus-associated lymphoid tissue (BALT) formation can be ca
Externí odkaz:
https://doaj.org/article/e49d1a15ec6a4960a1058210430c4751
Autor:
Georgios L. Moschovakis, Anja Bubke, Michaela Friedrichsen, Christine S. Falk, Regina Feederle, Reinhold Förster
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The chemokine receptor CXCR5 is primarily expressed on B cells and Tfh cells and facilitates their migration towards B cell follicles. In the present study we investigated the role of the CXCL13/CXCR5 axis in the pathogenesis of rheumatoid a
Externí odkaz:
https://doaj.org/article/26ad5b1349cb4222bb959cc284c84ee8
Autor:
Rodrigo Gutierrez Jauregui, Henrike Fleige, Anja Bubke, Manfred Rohde, Siegfried Weiss, Reinhold Förster
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Implant associated infections represent a serious health burden in clinics since some microorganisms are able to colonize biological surfaces or surfaces of indwelling medical devices and form biofilms. Biofilms represent communities of microorganism
Externí odkaz:
https://doaj.org/article/459d3e4f27e549bd9bb1870d2dd41508
Autor:
Swantje I. Hammerschmidt, Kathrin Werth, Michael Rothe, Melanie Galla, Marc Permanyer, Gwendolyn E. Patzer, Anja Bubke, David N. Frenk, Anton Selich, Lucas Lange, Axel Schambach, Berislav Bošnjak, Reinhold Förster
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
To present antigens to cognate T cells, dendritic cells (DCs) exploit the chemokine receptor CCR7 to travel from peripheral tissue via afferent lymphatic vessels to directly enter draining lymph nodes through the floor of the subcapsular sinus. Here,
Externí odkaz:
https://doaj.org/article/257304072d3544159c04aa87243fb8fc
Autor:
Christian Koenecke, Immo Prinz, Anja Bubke, Alina Schreder, Chun-Wei Lee, Oliver Pabst, Reinhold Förster
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38252 (2012)
Gut-homing of donor T cells is causative for the development of intestinal GvHD in recipients of allogeneic hematopoietic stem cell transplantation (HSCT). Expression of the gut-specific homing receptors integrin-α4β7 and chemokine receptor CCR9 on
Externí odkaz:
https://doaj.org/article/d0fba14454d04ee4a8d3e98d2330afaa
Publikováno v:
European Journal of Immunology. 51:2618-2632
The epidermis of mouse skin is usually populated by dendritic epidermal T cells (γδDETC) expressing an invariant Vγ5Vδ1+ TCR. In Tcrd-/- mice, skin-resident γδDETC are replaced by αβDETC carrying polyclonal αβ TCRs. Although they exhibit a