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of 8
pro vyhledávání: '"Anja Brenn"'
Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice
Autor:
Anja Brenn, Markus Grube, Michele Peters, Andrea Fischer, Gabriele Jedlitschky, Heyo K. Kroemer, Rolf W. Warzok, Silke Vogelgesang
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Neurovascular dysfunction is an important component of Alzheimer's disease, leading to reduced clearance across the blood-brain barrier and accumulation of neurotoxic β-amyloid (Aβ) peptides in the brain. It has been shown that the ABC transport pr
Externí odkaz:
https://doaj.org/article/01ea8722e052471899c4f3f8a87f7173
Autor:
Anja Brenn, Gabriele Jedlitschky, Andrea Fischer, Markus Grube, Martin Eiden, Markus Keller, Martin H. Groschup, Barbara Strohmeier, Silke Vogelgesang
Publikováno v:
Brain Pathology. 24:18-24
The adenosine triphosphate-binding cassette transport protein P-glycoprotein (ABCB1) is involved in the export of beta-amyloid from the brain into the blood, and there is evidence that age-associated deficits in cerebral P-glycoprotein content may be
Autor:
Silke Vogelgesang, Markus Keller, Martin H. Groschup, Anja Brenn, Sascha Bruckmann, Katharina Niedrig, Oliver von Bohlen und Halbach, Markus Grube, Silva Holtfreter
Publikováno v:
Current Alzheimer research. 14(6)
Background: Immunization against beta-amyloid (Aβ) reduces cerebral Aβ deposits and improves cognitive capacities in transgenic mouse models, and thus has been considered a promising disease- modifying therapeutic approach for Alzheimer’s disease
Publikováno v:
Current Pharmaceutical Design. 17:2778-2786
The blood-brain barrier (BBB) protects the brain against endogenous and exogenous compounds and plays an important part in the maintenance of the microenvironment of the brain. In particular, the importance of brain-to-blood transport of brain-derive
Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice
Autor:
Rolf Warzok, Heyo K. Kroemer, Andrea Fischer, Markus Grube, Silke Vogelgesang, Anja Brenn, Gabriele Jedlitschky, Michele Peters
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
International Journal of Alzheimer's Disease
International Journal of Alzheimer's Disease
Neurovascular dysfunction is an important component of Alzheimer's disease, leading to reduced clearance across the blood-brain barrier and accumulation of neurotoxicβ-amyloid (Aβ) peptides in the brain. It has been shown that the ABC transport pro
Publikováno v:
PROTEOMICS. 9:5199-5205
Cerebrospinal fluid (CSF) is considered as the most promising body fluid target for the discovery of biomarkers for early diagnosis of neurodegenerative diseases such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy in catt
Publikováno v:
Current pharmaceutical design. 17(26)
The blood-brain barrier (BBB) protects the brain against endogenous and exogenous compounds and plays an important part in the maintenance of the microenvironment of the brain. In particular, the importance of brain-to-blood transport of brain-derive
Autor:
Zhiyu Wang, Yanfei Wang, Prachi Vilekar, Seung-Pil Yang, Mayuri Gupta, Myong In Oh, Autumn Meek, Lisa Doyle, Laura Villar, Anja Brennecke, Imindu Liyanage, Mark Reed, Christopher Barden, Donald F. Weaver
Publikováno v:
PeerJ, Vol 8, p e9533 (2020)
The novel coronavirus SARS-CoV-2 has become a global health concern. The morbidity and mortality of the potentially lethal infection caused by this virus arise from the initial viral infection and the subsequent host inflammatory response. The latter
Externí odkaz:
https://doaj.org/article/d693a7d171bf48fd9f935c5c836eac85